1、国家自然科学基金面上项目，基于NOD1/RIP2/MAVS调控的心肌细胞线粒体稳态研究益气活血法防治心衰心肌重构的作用机制，82174106，2022年1月-2025年12月，主持

2、国家自然科学基金青年项目，丹红注射液通过外泌体miR-126调控心脏祖细胞Ras/ERK通路干预心梗后心肌修复的机制研究，81703850，2018年1月-2020年12月，主持

代表性论文：

[1]       Li SN, Liu ZH, Zhou MX, et al. Danhong Injection Up-regulatesmiR-125b in Endothelial Exosomes and Attenuates Apoptosis in Post-InfarctionMyocardium. Chin J Integr Med. 2023 .

[2]       Li S, Liu H, Li Y, et al. Shen-Yuan-Dan Capsule AttenuatesVerapamil-Induced Zebrafish Heart Failure and Exerts Antiapoptotic andAnti-Inflammatory Effects via Reactive Oxygen Species-Induced NF-κB Pathway.Front Pharmacol. 2021. 12: 626515.

[3]       Li S, Li P, Liu W, et al. Danhong Injection Alleviates CardiacFibrosis via Preventing the Hypermethylation of Rasal1 and Rassf1 in TAC Mice.Oxid Med Cell Longev. 2020. 2020: 3158108.

[4]       Li SN, Li P, Liu WH, et al. Danhong injection enhancesangiogenesis after myocardial infarction by activating MiR-126/ERK/VEGFpathway. Biomed Pharmacother. 2019. 120: 109538.

[5]       Li S, Nong Y, Gao Q, et al. Astragalus Granule Prevents Ca2+Current Remodeling in Heart Failure by the Downregulation of CaMKII. Evid BasedComplement Alternat Med. 2017. 2017: 7517358.