个人信息
Personal Information
联系方式
Contact Information
个人简介
Personal Profile
郑光辉， 医学博士，主任技师，副教授，硕士生导师，北京天坛医院检验科微生物与分子遗传部长,国家药监局体外诊断试剂质量控制重点实验室副主任, 卫健委人才中心临床医学检验专业专家，北京市科协人才举荐评审专家。主要工作方向为神经系统感染性疾病的诊断，包括生物标志物的研究，微生物耐药基因的筛查，耐药菌的作用机制，质谱检测等。2013年毕业于北京协和医学院，以第一或通讯作者发表SCI论文21篇，总IF>100分，最高15.4，中文核心期刊论文18篇, 主持12项课题，获得国家重点研发计划子课题，国家卫建委医学人才培养计划、 “北京市优秀人才”，入选北京市医管局“青苗计划”、“培育计划”，“青年人才托举工程项目”，以主要发明人（前三）申报并获批国家发明专利三项。获得北京市大学生优秀毕业设计指导教师奖，首都医科大学教学奖，首都医科大学青年教学奖，首都医科大学科技进步二等奖（第二），目前担任Frontiers in Neurology客座主编，Interdisciplinary Medicine青年编委， Infectious medicine青年编委，中华药械研究与临床杂志青年编委，中国抗生素杂志青年编委，“首都卫生发展项目”评审专家，《中华实验与临床病毒学杂志》特约审稿人，《国际检验医学杂志》特约审稿人，中国生物医学工程学会医检工程分会青年委员会副主任委员，北京医学会检验医学分会青年委员等十余项学术任职。
1. 2015年，北京天坛医院青年基金。基金号：2015-YQN-06
2. 2017年，“北京市优秀人才”青年骨干项目。基金号：2017000021469G270
3. 2018年，北京市医管局“青苗计划”项目。基金号：QML20180502
4. 2018年，首都医科大学本科生科研创新项目
5. 2019年，首都医科大学“培育计划”项目（PYZ19116）
6. 2019年，北京科学技术协会“青年人才托举工程项目”
7. 2020年，北京天坛医院自然基金（YZR-2020-15）
8. 2021年，首都医科大学本科生科研创新项目，基于HPLC-MS/MS的神经系统感染性疾病患者脑脊液代谢组学的研究，基金号：XSKY2021
9. 2021年，北京市医管中心“培育计划”。基金号：PX2022021
10. 2022年，国家卫生健康委医学人才培养计划,基金号：MTP2022A011.
1. Zheng GH, Shen JJ, Zhan YC, Yi H, Xue ST, Wang Z, Ji XY, Li ZR: Design, synthesis and in vitro and in vivo antitumour activity of 3-benzylideneindolin-2-one derivatives, a novel class of small-molecule inhibitors of the MDM2-p53 interaction. Eur J Med Chem 2014, 81:277-288.
2. Zhang G, Zheng G, Zhang Y, Ma R, Kang X: Evaluation of a micro/nanofluidic chip platform for the high-throughput detection of bacteria and their antibiotic resistance genes in post-neurosurgical meningitis. Int J Infect Dis 2018, 70:115-120.
3. Guanghui Z, Jing L, Guojun Z, Hong L: Epidemiology and risk factors of neurosurgical bacterial meningitis/encephalitis induced by carbapenem resistant Enterobacteriaceae. J Infect Chemother 2020, 26:101-106.
4. Qian L, Shi Y, Li F, Wang Y, Ma M, Zhang Y, Shao YW, Zheng G, Zhang G: Metagenomic Next-Generation Sequencing of Cerebrospinal Fluid for the Diagnosis of External Ventricular and Lumbar Drainage-Associated Ventriculitis and Meningitis. Front Microbiol 2020, 11:596175.
5. Shi YJ, Zheng GH, Qian LY, Qsman RA, Li GG, Zhang GJ: Longitudinal Analysis of Risk Factors for Clinical Outcomes of Enterobacteriaceae Meningitis/Encephalitis in Post-Neurosurgical Patients: A Comparative Cohort Study During 2014-2019. Infect Drug Resist 2020, 13:2161-2170.
6. Zheng G, Ji X, Yu X, Liu M, Huang J, Zhang L, Guo D, Zhang G: Development and verification of a discriminate algorithm for diagnosing post-neurosurgical bacterial meningitis-A multicenter observational study. J Clin Lab Anal 2020, 34:e23069.
7. Zheng G, Li S, Zhao M, Yang X, Zhang Y, Deng J, Luo Y, Lv H, Zhang G: Time to positive culture can differentiate post-neurosurgical coagulase-negative Staphylococci other than S epidermidis meningitis from contamination: A case-control observational study. J Clin Lab Anal 2020, 34:e23447.
8. Zheng G, Zhang Y, Zhang L, Qian L, Cai Y, Lv H, Kang X, Guo D, Wang X, Huang J, et al.: Evaluation of a micro/nanofluidic chip platform for diagnosis of central nervous system infections: a multi-center prospective study. Sci Rep 2020, 10:1568.
9. Ding Y, Shi Y, Wang L, Li G, Osman RA, Sun J, Qian L, Zheng G, Zhang G: Potential biomarkers identified by TMT-based quantitative proteomics for diagnosis and classification of Guillain-Barré syndrome. Eur J Neurol 2021 .
10. Hong L, Hongmei W, Leijie X, Dandan Z, Peng L, Zhifei H, Ruimin M, Yijun S, Guanghui Z, Guojun Z: Serum ceramide concentrations are associated with depression in patients after ischemic stroke-A two-center case-controlled study. Clin Chim Acta 2021, 518:110-115.
11. Shi Y, Ding Y, Li G, Wang L, Osman RA, Sun J, Qian L, Zheng G, Zhang G: Discovery of Novel Biomarkers for Diagnosing and Predicting the Progression of Multiple Sclerosis Using TMT-Based Quantitative Proteomics. Front Immunol 2021, 12:700031.
12. Sun B, Kang X, Yue S, Lan L, Li R, Chen C, Zhang W, He S, Zhang C, Fan Y, et al.: A rapid procedure for bacterial identification and antimicrobial susceptibility testing directly from positive blood cultures. Analyst 2021 .
13. Zheng G, Cao Y, Liu C, Qian L, Cai Y, Cui M, Sun H, Hong L, Yuan J, Zhang L, et al.: Phenotype, molecular characterisation and risk factors for postoperative meningitis caused by ESBL-producing-Enterobacteriaceae: a six years multi-Centre comparative cohort study. BMC Infect Dis 2021, 21:85.
14. Zheng G, Zhang C, Zhang G, Shao C: Evaluation of the Diagnostic and Prognostic Value of CSF Presepsin Levels in Patients with Postneurosurgical Ventriculitis/Meningitis. Infect Drug Resist 2021, 14:2901-2909.
15. Zheng G, Shi Y, Cao Y, Qian L, Lv H, Zhang L, Zhang G: Clinical Feature, Therapy, Antimicrobial Resistance Gene Distribution, and Outcome of Nosocomial Meningitis Induced by Multidrug-Resistant Enterobacteriaceae-A Longitudinal Cohort Study From Two Neurosurgical Centers in Northern China. Front Cell Infect Microbiol 2022, 12:839257.
16. Zheng G, Wang S, Lv H, Zhang G: Nomogram Analysis of Clinical Characteristics and Mortality Risk Factor of Non-Fermentative Gram-Negative Bacteria-Induced Post-Neurosurgical Meningitis. Infect Drug Resist 2022, 15:6379-6389.
17. Sun J, Shi Y, Ding Y, Wang S, Qian L, Luan X, Li G, Chen Y, Li X, Lv H, et al.: Effect of Follow-Up Cerebrospinal Fluid Cultures in Post-Neurosurgical Patients' Outcome with Gram-Negative Bacterial Meningitis/Encephalitis. Infect Drug Resist 2023, 16:6285-6295.
18. Wang L, Zhang Q, Zhang Y, Zheng G, Wang K, Wu Z, Zhang J, Jia W, Zhang G: Insufficiency of plasmatic arginine/homoarginine during the initial postoperative phase among patients with tumors affecting the medulla oblongata heightens the likelihood of neurogenic pulmonary edema following surgery. Int J Surg 2023 .
19. Zheng G, Shi Y, Sun J, Wang S, Li X, Lv H, Zhang G: Effect of antibiotic prophylaxis in the prognosis of Post-neurosurgical meningitis patients. Eur J Med Res 2023, 28:396.
20. Cui A, Yang H, Yi H, Lv M, Peng X, Zheng G, Li Z: Design, synthesis, and bioactivity investigation of novel cyclic lipopeptide antibiotics targeting top-priority multidrug-resistant gram-negative bacteria. Eur J Med Chem 2024 :116924.
21. Zheng G, Shi Y, Sun J, Wang S, Qian L, Lv H, Zhang G, Chen K: Clinical Characteristics and Predictors of Mortality of Patients with Post-Neurosurgical Meningitis-A 900-Cases Cohort Study. Infect Drug Resist 2024 :4853-4863.
文件上传中...
