1.       国家自然科学基金面上项目，82570072，肠道菌B.obeum代谢产物D-阿洛糖抑制肺动脉内皮铁死亡改善特发性肺动脉高压的作用机制，2026/01-2029/12，49万元，在研，主持。

2.       国家自然科学基金面上项目，82170302，长链非编码RNA/SNHG29在体-肺分流性肺动脉高压肺血管重构中的作用与机制，2022/01-2025/12，55万元，在研，主持；

3.       北京市呼吸疾病研究所“预算编制项目”子课题，Ysbz2025007，肠道微生态在肺动脉高压中的作用与机制研究，2025/01-2027/12，414万元，在研，主持；

1. 重要学术论文

（1）      Chen Y#, Chen Z#, Liang L#, Li J#, Meng L, Yuan W, Xie B, Zhang X, Feng L, Jia Y, Fu Z, Su P, Tong Z*,Zhong J*, Liu X*. Multi-kingdom GutMicrobiota Dysbiosis is Associated with the Development of Pulmonary ArterialHypertension. EBioMedicine. 2025; 115:105686. 

（2）      An K#, Jia Y#, Xie B#, Gao J#, Chen Y, Yuan W,Zhong J*, Su P*, Liu X*. Alterations in the gut mycobiome with coronary artery disease severity. EBioMedicine,2024, 103, 105137 

（3）      Fu Z#, Jia Y#, Zhao J, Guo Y, Xie B, An K, Yuan W, Chen Y, Zhong J, TongZ, Liu X* and Su P*. Perioperative Multi-Kingdom Gut Microbiota Altersin Coronary Artery Bypass  Grafting.BIOMEDICINES. 2025; 13(2). 

（4）      Wan L#, Wang H#, Liang Y#, Zhang X#, Yao X, Zhu G, Cai J, Liu G, Liu X,Niu Q, Li S, Zhang B, Gao J, Wang J, Shi X, Hu L, Liu X*, Zou Z*, Yang G*. 2024. Effect of oral faecal microbiota transplantationintervention for children with autism spectrum disorder: A randomised, double‐blind, placebo‐controlled trial.Clinical and Translational Medicine, 2024, 14(9) e70006. 

（5）      Liu X#, Zhang Y#, Yuan W, Han R, Zhong J, Yang X*,Zheng M*, Xie B*. Exosomal CircRNAs in Circulation Serve as Diagnostic Biomarkers for AcuteMyocardial Infarction. Front Biosci (Landmark Ed). 2024;29(4):149. 

（6）      Chen Y#, Meng L#, Yuan W, Gao Z, Zhang X, Xie B, Song J, Li J, Zhong J*and Liu X*. Gut Fungal Microbiota Alterations in Pulmonary Arterial HypertensiveRats. Biomedicines. 2024; 12(2):298. 

（7）      Liu X#, Zheng M#, Han R#, Yu Z, Yuan W, Xie B, Zhang Y,Zhong J, Wang L, Wang L* and Liu X*. Circulating Exosomal CircRNAs asDiagnostic Biomarkers for Chronic Coronary Syndrome. METABOLITES. 2023;13(10):1066.

（8）      Zheng M#, Han R#, Yuan W#, Chi H, Zhang Y, Sun K, Zhong J*, Liu X* and Yang X*.Circulating exosomal lncRNAs in patients with chronic coronary syndromes. ARCHMED SCI. 2023; 19(1):46-56. 

（9）     Chen Y, Yuan W, Meng L, ZhongJ*, Liu X*, The Role and Mechanism of Gut Microbiota inPulmonary Arterial Hypertension. Nutrients. 2022 Oct 13;14(20):4278.

（10）   Liu X#, Chen Z#, Li S#, Jin L, Cui X, Cui C, Deng Y, Gao Q, Fan L, Niu Y, WangW, Cui C, Zhong J, Cui Q*, Geng B* and Cai J*. Pre-miRNA Hsa-Let-7a-2: a NovelIntracellular Partner of Angiotensin II Type 2 Receptor Negatively Regulatingits Signals. INT J BIOL SCI. 2022; 18(8):3237-3250. 

（11）   Meng L#, Yuan W#, Chi H, Han R, Zhang Y, Pan X, Meng J, Liu Y, Song J,Zhong J*, Liu X*, Genetic deletion ofCMG2 exacerbates systemic-to-pulmonary shunt-induced pulmonary arterialhypertension. FASEB J. 2021; 35(4):e21421.

（12）   Meng L, Teng X, Liu Y, Yang C, Wang S, Yuan W, Meng J, Chi H, Duan L*& Liu X*. Vital Roles ofGremlin-1 in Pulmonary Arterial Hypertension Induced by Systemic-to-PulmonaryShunts. J Am Heart Assoc 2020; Aug 4;9(15):e016586.

（13）   MengL#, Liu X#, Teng X, Yuan W,Meng J, Li J, Zheng Z, Wei Y, Hu S*. DAN plays important compensatory roles insystemic-to-pulmonary shunt associated pulmonary arterial hypertension. ActaPhysiol (Oxf), 2019 Feb 4:e13263. 

（14）   MengL#, Liu X#, Teng X, Gu H, Yuan W, Meng J, Li J, Zheng Z, Wei Yand Hu S: Osteopontin plays important roles in pulmonary arterial hypertensioninduced by systemic-to-pulmonary shunt. The FASEB Journal,2019 33(6):7236-7251.

（15）  Zheng M#, Liu X#,Han R#, Yuan W, Sun K, Zhong J*, Yang X*. Circulating Exosomal Long NoncodingRNAs in Patients with Acute Myocardial Infarction. J Cell Mol Med. 2020Aug;24(16):9388-9396.

（16）   Liu X, Yuan W, Yang L, Li J, Cai J. miRNA Profiling of Exosomes from Spontaneous Hypertensive Rats UsingNext-Generation Sequencing. Journal of Cardiovascular TranslationalResearch. 2019 Feb;12(1):75-83. 

（17）  LiuX, Yuan W, Li J, Yang L, Cai J. ANTXR2Knock-Out Does Not Result in the Development of Hypertension in Rats. Am JHypertens. 2017; 30(2): 182-187. 

（18）  Liu X#, MengL#, Li J, Meng J, Teng X, Gu H, Hu S* & Wei Y*. Secretoryclusterin is upregulated in rats with pulmonary arterial hypertension inducedby systemic-to-pulmonary shunts and exerts important roles in pulmonary arterysmooth muscle cells. Acta Physiologica 2015;213(2):505-518.

（19）  Liu X#,Meng L#, Shi Q, Liu S, Cui C, Hu S*, Wei Y*. Dermatopontin promotes adhesion,spreading and migration of cardiac fibroblasts in vitro. Matrix Biology 2013;32(1): 23-31.

（20）   Meng L#, Liu X#, Zheng Z, Li J, Meng J, Wei Y*, HuS*. Original rat model of high kinetic unilateral pulmonary hypertensionsurgically induced by combined surgery. The Journal of Thoracic andCardiovascular Surgery 2013; 146(5): 1220-26.

（21）   Liu X#, Hu C#, Bao M#, Li J#, LiuX#, Tan X, Zhou Y, Chen Y, Wu S, Chen S, Zhang R, Jiang F, Jia W, WangX*, Yang X*, Cai J*. Genome Wide Association Study Identifies L3MBTL4as a Novel Susceptibility Gene for Hypertension. ScientificReports 6(1). 2016, 6:30811.  

2. 重要奖项

(1) 呼吸危重症&肺动脉高压前沿一带一路青年呼吸论坛优秀青年学者奖

(2) 首都医科大学2023年度科技奖励自然科学奖 二等奖