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北京协和医学院医学博士，相继在美国密歇根大学、希望之城医学中心及西达赛奈医学中心从事科研工作，主要研究DNA损伤和表观遗传在肿瘤发生发展过程中的作用，相关研究成果发表于Nature Communications、Nucleic Acids Research和Elife等知名期刊。
2021 北京市人才项目（在研）
2021 首都医科大学宣武医院汇智人才项目（在研）
1 Bian C, Zhang C, Luo T, Yang Y,Kong M, Yu X. (2019) NADP+ is anendogenous PARP inhibitor in DNA damage response and tumor suppression. NatureCommunications Feb 11;10(1):693
2 Bian,C., and Yu, X. (2014) PGC7 suppresses TET3 for protecting DNA methylation. NucleicAcids Res 42, 2893-2905
3 Bian C, Chen Q, Yu X. (2015) The zinc finger proteins ZNF644 andWIZ regulate the G9a/GLP complex for gene repression. Elife Mar 19;4. 05606.
4 Chen Q, Bian C, Wang X, Liu X, Ahmad Kassab M, Yu Y, Yu X. ADP-ribosylation of histonevariant H2AX promotes base excision repair. EMBOJ. 2021 Jan 15;40(2):e104542
5 Chen, Q., Chen, Y., Bian,C., Fujiki, R., and Yu, X. (2013) TET2 promotes histone O-GlcNAcylationduring gene transcription. Nature 493, 561-564
6 Li M, Bian C*, Yu X. (2014) Poly(ADP-ribosyl)ationis recognized by ECT2 during mitosis. Cell Cycle 13(18):2944-51. (* Co-firstauthor)
7 Zhang F, Shi J, Bian C, Yu X.Poly(ADP-Ribose) Mediates the BRCA2-Dependent EarlyDNA Damage Response. Cell Rep. 2015 Oct 27;13(4):678-89.
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