1. γ-分泌酶剪切K v2.1通道对阿尔茨海默病的干预及机制研究，国家自然基金委青年项目，2023-2025，主持

2. SCD转化为阿尔茨海默病新机制及其预警和干预体系的研究，科技创新2030-重大项目脑科学与类脑研究”专项，2022-2027，骨干

3. 阿尔茨海默病与2型糖尿病的分子关联研究，首都医科大学优秀青年人才项目(B类), 2023-2025，主持

4. 脑内hIAPP诱导阿尔茨海默病发生及其相关机制的研究，北京市医院管理中心“青苗”计划，2022-2023，主持

5. 人工智能动态血糖检测对糖尿病引发认知障碍的干预效果，北京市属医学科研院所公益发展改革试点项目，2021-2023，骨干

6. T2DM引发AD的分子机制研究，首都医科大学宣武医院“汇智”人才工程，2021-2023，主持

一、近五年重要学术论文

1.  Yao J,Wang Z, Song W#, Zhang Y#. (2023). Targeting NLRP3inflammasome for neurodegenerative disorders. Molecular Psychiatry. Published onlineon September 5th. (# 共同通讯）

2.  ZhangY#，Chen H，Li R，SterlingK, Song W#. (2023). Amyloid β-based therapy for Alzheimer’s disease:challenges, successes and future. Signal Transduction and TargetedTherapy  8:248. (# 共同通讯）

3. Cai F*^#, Song B*,Yang Y, Liao H, Li R, Wang Z, Cao R, Chen H, Wang J, Wu Y, Zhang Y^#,Song W^#. (2023). USP25 contributes to defective neurogenesis andcognitive impairments. The FASEB Journal  37:e22971. (# 共同通讯）

4. WangD*, Yang H*, Zhang Y*, Hu R, Hu D,Wang Q, Liu Y, Liu M, Meng Z, Zhou W, Song W. (2021). Inhibition ofcystathionine β-synthase promotes apoptosis and reduces cell proliferation inchronic myeloid leukemia. Signal Transduction and Targeted Therapy6:52. (*共同第一)

5. Fei X*, Zhang Y*, Mei Y*, Yue X*, Jiang W, AiL, Yu Y, Luo H, Li H, Luo W, Yang X, Lv J, He R, Song W, Tong Z. (2020).Degradation of FA reduces Aβ neurotoxicity and Alzheimer-related phenotypes. MolecularPsychiatry 26:5578-5591. (*共同第一)

6. Zhang Y*, Peng L* and Song W. (2020). Mitochondriahyperactivity contributes to social behavioral impairments. SignalTransduction and Targeted Therapy  5:126.(*共同第一)

7. Zhang Y, Dong Z and Song W. (2020). NLRP3 inflammasome as anovel therapeutic target for Alzheimer’s disease. Signal Transduction andTargeted Therapy  5:37.

8. Zhang S*, Zhao J*, ZhangYH*, Zhang Y*, Cai F, Wang L, SongW. (2019) Upregulation of MIF as a defense mechanism and a biomarker of Alzheimer’sdisease. Alzheimer Research and Therapy 11(1): 54.(*共同第一)

9. Liu F*, Zhang Y*, Liang Z,Sun Q, Liu H, Zhao J, Xu J, 9. Zheng J, Yun Y, Yu X, Song W, Sun X. (2018).Cleavage of Potassium Channel Kv2.1 by BACE2 Reduces Neuronal Apoptosis. MolecularPsychiatry 23(7): 1542-1554.(*共同第一)

10. Zhang Y, Song W.(2017). Islet Amyloid Polypeptide: Another Key Molecule in Alzheimer’sPathogenesis? Progress in Neurobiology 153: 100-120.

二、重要奖项

国际神经化学协会（International Society for Neurochemistry), 青年学者奖（Young Investigator Colloquia Award), 2019