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1. 国家自然科学基金面上项目,81873119,基于REV-ERBα/RORγt调控Th17细胞分化探讨昼夜节律对银屑病的影响及凉血解毒方干预机制研究,56万元,进行,主持。
2. 国家自然科学基金青年项目,81603630,基于TNF-α/PPAR-β/δ通路探讨凉血解毒方对银屑病合并脂代谢紊乱的调控机制,17万元、已结题,主持。
1. Sun L, Guo X, Qin Y, Li P, Yu C,Gao X, Xie X*,Xu X*(共同通讯).Serum Intestinal Metabolites are Raised in Patients with Psoriasis andMetabolic Syndrome. Clin Cosmet Investig Dermatol. 2022 May 13;15:879-886.
2.Xie X, Zhang L, Li X, Liu W, Wang P, Lin Y, Han X andLi P (2021) Liangxue Jiedu Formula Improves Psoriasis and DyslipidemiaComorbidity via PI3K/Akt/mTOR Pathway. Front. Pharmacol. 12:591608.
3. Lin Y, He X, Xie X, LiuQ, Chen J, Li P*. Huiyang Shengji Extract Improve Chronic Nonhealing Cutaneousthrough the TGF- β 1/Smad3 Signaling Pathway. Evid Based Complement AlternatMed. 2021 Jun 9;2021:8881565.
4. Li X, Xie X, Zhang L, Meng Y, Li N, Wang M, Zhai C,Liu Z, Di T, Zhang L, Li P*. Hesperidin inhibitskeratinocyte proliferation and imiquimod-induced psoriasis-like dermatitis viathe IRS-1/ERK1/2 pathway [J]. Life Sci. 2019(219): 311-21.
5. Xie X, Zhang L, Lin Y, Wang Y,Liu W, Li X, Li P*. Imiquimod induced ApoE-deficient mice might be acomposite animal model for the study of psoriasis and dyslipideamiacomorbidity[J]. J Dermatol Sci,2017(88).20-28.
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