1)       国家自然科学基金面上项目，82272867， c-MYC通过招募METTL3介导自身靶基因转录本m6A修饰导致胶质瘤化疗抵抗的作用和机制， 2023.01-2026.12, 51万，主持。

2)       北京市科技新星计划，Z201100006820118，神经胶质瘤临床分子病理整合检测方法的开发及应用，2020.09-2023.08,40万，主持。

3)       国家自然科学基金青年科学基金项目，81903078， m6A识别蛋白YTHDF2调控UBXN1/NF-κB信号轴参与恶性进展胶质瘤化疗抵抗的机制研究， 2020.01-2022.12, 20.5万，主持。

4)       首都医科大学附属天坛医院青年科学家计划, WTAP/HuR 通过 RNA m6A 修饰调控 ANXA2表达促使胶质瘤间质型特征增强,2023.01-2025.12, 40万，主持。

5）    北京市神经外科研究所重大前沿科技基金，基于多组学整合分析的脊髓胶质瘤的精准分子分型与个体化靶向治疗，2024.01-2024.12，50万，主持。

6)       国家自然科学基金面上项目，82172783，METTL3通过m6A修饰调控MALAT1/EZH2/NFκB环路参与脊髓胶质瘤原发性化疗抵抗的机制研究，2022.1-2025.12，66万元，参加

7)  国家重点研发计划项目中-瑞国际合作，2019YFE0108100基于分子分型的脑胶质瘤和急性白血病精准诊断，2020.1-2022.12，101.7万元，子课题（中方）参加

1. 1)       Mu QH#, Chai RC#,Pang B, Yang YX, Liu HJ, Zhao Z, Bao ZS, Song D, Zhu ZH, Yan ML,Jiang BB, Mo ZC, Tang JH, Sa JK, Cho HJ, Chang YZ, Chan KHY, Loi DSC, Tam SST,Chan AKY, Wu AR, Liu ZQ, Poon WS, Ng HK6, Chan DTM, Iavarone A*,Nam DH*, Jiang T*, Wang JG*. Identifyingpredictors of glioma evolution from longitudinal sequencing. ScienceTranslational Medicine, 2023 Oct 4;15(716), eadh4181, [IF=17.1]JCR: Q1 中科院1区

   2)       Chai RC#*, Yan H#, An SY, Pang B,Chen HY, Mu QH, Zhang KN, Zhang YW, Liu YQ, Liu X, Zhao Z, Jiang T, Wang YZ*,Jia WQ*. Genomic profiling and prognostic factors of H3 K27M-mutant spinal corddiffuse glioma, Brain Pathology, 2023;e13153, [IF=6.4] JCR: Q1 中科院病理学1区

   3)       ChaiRC#,Fang SY#, Pang B, Liu YQ, Wang YZ, Zhang W, Jiang T*. Molecular pathology andclinical implications of diffuse glioma. Chin Med J (Engl). 2022 Dec20;135(24):2914-2925. [IF=6.1] JCR: Q1 中科院2区

   4)       ZhangKN#, Liu X, Li GZ, Chang X, Li SW, Chen J, Zhao Z, Wang JG, Jiang T*, ChaiRC*, Clinical management and survival outcomes of patients with differentmolecular subtypes of diffuse gliomas in China (2011-2017): a multicenterretrospective study from CGGA, Cancer Biol Med, 2022. Doi:10.20892/j.issn.2095-3941.2022.0469,[IF=5.5] JCR: Q1 中科院2区

   5)       WuLX#, Chai RC#, Zhao Z, Wang QH*, Jiang T*. Role of the tumormicroenvironment in shaping IDH-wildtype glioma plasticity, and potentialtherapeutic strategies, Cancer Biol Med, 2022 Nov 1;19(10):1423-1427,  [IF=5.5] JCR: Q1 中科院2区

   6)       Chai RC#, Liu X#, Pang B, Liu YQ,Li JJ, Li YF, Zhao Z, Du J, Bao ZS, Jiang T*. Recurrent PTPRZ1-MET fusion and ahigh occurrence rate of MET exon 14 skipping in brain metastases. CancerScience. 2022 Feb;113(2):796-801. doi: 10.1111/cas.15211. [IF=5.7] JCR: Q2 中科院2区

   7)       Chai RC#*,Chang YZ#, Chang X, Pang B, An SY, Zhang KN, Chang YH Jiang T*, Wang YZ*.YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediatedm6A modification to activate NF-κB and promote the malignant progression ofglioma, Journal of Hematology & Oncology, 2021, 14: 109.[IF= 28.5] JCR: Q1 中科院1区

   8)       Chang YZ#,Chai RC#*,Pang B#, Chang X, An SY,Zhang KN, Jiang T, Wang YZ*. METTL3 enhances the stability of MALAT1 withthe assistance of HuR via m6A modification and activates NF-κB to promote themalignant progression of IDH-wildtype glioma, Cancer Letters, 2021 Jul28;511:36-46. doi: 10.1016/j.canlet.2021.04.020. [IF=9.7] JCR: Q1 中科院1区

   9)       Chai RC#，Li GZ#, Liu YQ, Zhang KN, Zhao Z, Wu F, Chang YZ, Pang B, Li JJ, LiYF, Jiang T*, Wang YZ*. Predictive value of MGMT promoter methylation on thesurvival of TMZ treated IDH-mutant glioblastoma, Cancer Biol Med, 2021 Feb15;18(1):272-282. [IF=5.5] JCR:Q2 中科院2区

   10)     Chai RC#, Zhang YW#, Liu YQ, Chang YZ, Pang B, Jiang T,Jia WQ*, Wang YZ*. The molecular characteristics of spinal cord gliomas with orwithout H3 K27M mutation. Acta Neuropathol Commun, 2020, 8(1):40 [IF= 7.1]JCR: Q1 中科院2区

   11)     Chai RC#, LiYM#, Zhang KN, Chang YZ, Liu YQ, Zhao Z, Wang ZL, Chang YH, Li GZ, Wang KY, WuF* Wang YZ*. RNA processing genes characterize RNA splicing and furtherstratify lower-grade glioma, JCI insight, 2019, 4:e130591 [IF= 8] JCR:Q1 中科院1区

   12)     Chai RC,Zhang KN, Chang YZ, Wu F, Liu YQ, Zhao Z, Wang KY, Chang YH, Jiang T*, WangYZ*, Systematically characterize the clinical and biological significances of1p19q genes in 1p/19q non-codeletion glioma, Carcinogenesis, 2019,40(10):1229-1239 [IF= 4.7] JCR:Q2 中科院2区

   13)     Chai RC#, WangN#, Chang YZ, Zhang KN, Li JJ, Niu JJ, Wu F*, Liu YQ*, Wang YZ*, Systematicallyprofiling the expression of eIF3 subunits in glioma reveals the expression ofeIF3i has prognostic value in IDH-mutant lower grade glioma, Cancer Cell Int,2019, 19:155, eCollection. [IF= 5.8] JCR: Q1 中科院2区

   14)     Wu F*#, Chai RC#, Wang ZL#, Liu YQ, ZhaoZ, Li GZ, Jiang HY, Molecular classification of IDH-mutant glioblastomas basedon gene expression profiles, Carcinogenesis, 2019,40:853 [IF= 4.8] JCR:Q2 中科院2区

   15)    Chai RC#, LiuYQ#, Zhang KN#, Wu F, Zhao Z, Wang KY, Jiang T, Wang YZ*, A novel analyticalmodel of MGMT methylation pyrosequencing offers improved predictive performancein patients with gliomas, Mod Pathol, 2019, 32:4-15. [IF=7.5] JCR: Q1 中科院1区

   16)    Chai RC#, Zhang KN#, Liu YQ, Wu F, Zhao Z, Wang KY, Jiang T, Wang YZ*, Combinationsof four or more CpGs methylation present equivalent predictive value for MGMTexpression and temozolomide therapeutic prognosis in gliomas, CNSNeurosci Ther, 2019, 25:314-322. [IF= 5.5] JCR: Q1 中科院1区

   17)    LiuYQ#, Chai RC#, Wang YZ, Wang Z, Liu X, Wu F*,Jiang T*, Amino acid metabolism-related gene expression-based risk signaturecan better predict overall survival for glioma, Cancer Sci, 2019, 110:321-333. [IF=5.7] JCR: Q2 中科院2区

   18)     Chai RC#, Zhang KN#, Wang KY#, Li GZ, Huang RY, ZhaoZ, Liu Y, Chen J*, A novel gene signature based on five glioblastoma stem-likecell relevant genes predicts the survival of primary glioblastoma, J Cancer ResClin Oncol. 2018, 144:439-447. [IF= 3.6] JCR: Q2 中科院3区

   19)    LiangHJ#, Chai RC#, Li X#, Kong JG, JiangJH, Ma J, Vatcher G, Yu AC, Astrocytic exportin-7 responds to ischemia throughmediating LKB1 translocation from the nucleus to the cytoplasm, J Neurosci Res,2015, 93:253. [IF= 4.162]

   20)    Chai RC,Jiang JH, Wong AYK, Jiang F, Gao K, Vatcher G, Yu AC*. AQP5 is differentiallyregulated in astrocytes during metabolic and traumatic injuries. Glia,2013,61:1748. [IF= 7.450] JCR: Q1 中科院1区