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自2010年7月留学回国后,在首都医科大学附属北京安贞医院-北京市心肺血管疾病研究所主要从事炎症微环境在心血管疾病病理性重构过程中机制研究。目前主要研究肺动脉高压和哮喘,涉及分子病因学、病理生理学、代谢组学等领域。
1. 国家自然基金面向项目《慢性低氧激活补体替代途径通过C3a/C3aR轴促进肺动脉高压机制研究》(2022/01-2025/12, 82170409)主持;
2. 国家自然基金面向项目《补体替代途径调控平滑肌细胞稳态及炎症反应促进主动脉夹层的发生机制研究》(2018/01-2021/12, 81770468)主持;
3. 国家自然基金青年基金项目《补体C5a信号通路通过调节肿瘤相关巨噬细胞分化促进肿瘤转移机制研究》(2014/01-2016/12, 81301797)主持;
4. 北京市自然科学基金项目《补体信号通路调节平滑肌细胞表型转化而促进主动脉瘤/夹层的发生机制研究》(2016/01-2018/12,7162030)主持;
5. 北京市自然科学基金项目《补体调节肿瘤微环境促进肿瘤血管新生的机制研究》(2011/01-2014/12,7122026)主持;
6. 教育部留学回国人员科研启动基金项目《JNK2调节肿瘤间质细胞的衰老促进肿瘤血管新生机制研究》(2013/01-2014/12,2013)主持。
1. Liu TT, Zhang Z, Deng J, Shi CY, Zheng S, Jia LX, Du J, PiaoC*. CXCL16 knockout inhibit asthma airway inflammation by suppressingH2-DM molecular mediated antigen presentation. Cell Death Discov, 2025, 11(1): 90.
2. Piao C#, Zhang WM#,Deng J, Zhou M, Liu TT, Zheng S, Jia LX, Song WC, Liu Y, Du J. Activation ofthe alternative complement pathway modulates inflammation in thoracic aorticaneurysm/dissection. Am J Physiol Cell Physiol. 2024 Feb 1;326(2):C647-C658.
3. Liu TT, Zheng S, Jia LX, Du J, Piao C*.Exploring the Regulatory Mechanism of CXCL16 Molecule-Related AntigenPresentation Using lncRNA-mRNA Co-Expression Network Analysis. J Inflamm Res.2024 Dec 24; 17: 11561-11575.
4. Deng J, Wei RQ, Zhang WM, Shi CY, Yang R, Jin M*,Piao C*. Crocin's role in modulating MMP2/TIMP1 and mitigatinghypoxia-induced pulmonary hypertension in mice. Sci Rep. 2024 Jun3;14(1):12716.
5. Piao C#, Li J#, Liang C#, Zhang J,Li X, Zhao Z, Wang K*. Effectof vitamin D on pregnancy in women with polycystic ovary syndrome:retrospective and prospective studies. Reprod Biomed Online. 2024 Feb 23;49(2):103909.
6. Liu TT, Wang YL, Zhang Z, Jia LX, Zhang J, Zheng S, Chen ZH, ShenHH, Piao CM*, Du J*. Abnormal adenosine metabolism of neutrophilsinhibits airway inflammation and remodeling in asthma model induced byAspergillus fumigatus. BMC Pulm Med. 2023 Jul 14;23(1):258.
7. Piao C#, Wang WJ#, Deng Y, Wang K*. Clinicaloutcomes of pulmonary hypertension in pregnancy among women with congenitalheart disease in China. J Matern Fetal Neonatal Med. 2023 Dec;36(1):2183349.
8. Liu Y, Deng J, Zhao Y, Liu K, Zhang W, Wang Q*, Wang J*, Piao C*. Outcomes of pregnancy in mice with pulmonary hypertension inducedby Hypoxia/SU5416. Biochem Biophys Res Comm, 2023 Aug; 669, 128-133.
9. Wei RQ, Zhang WM, Liang Z, Piao C*, Zhu G*.Identification of Signal Pathways and Hub Genes of Pulmonary Arterial Hypertensionby Bioinformatic Analysis. Can Respir J. 2022 Aug 29; 2022: 1394088.
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