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博士,主任医师,副教授,硕士生导师,博士毕业于首都医科大学病原微生物学系,2007年于首都医科大学附属北京友谊医院北京热带医学研究所工作,2018-1019年于美国约翰斯·霍普金斯大学分子微生物学与免疫学系做访问学者工作。致力于寄生虫病、热带病研究,第一作者发表SCI文章及统计源期刊文章20余篇。曾获教育部科技进步二等奖等荣誉。
北京热带医学研究所,创建于1978年,是我国成立最早的,也是我国北方地区唯一的热带医学研究所。首任所长为中国科学院院士我国著名热带病专家、北京友谊医院首任院长钟惠澜教授,叶剑英元帅亲笔为研究所题名。我所是全国最早被WHO任命的世界卫生组织(WHO)合作中心,自1981年起曾先后任世界卫生组织利什曼病、肝吸虫病、肺吸虫病合作中心。
(1) 国家自然科学基金委员会, 青年科学基金项目, 82001749, 基于登革病毒多功能T细胞表位的疫苗设计
和免疫保护作用研究, 2021-01-01 至 2023-12-31, 24万元, 结题, 主持
(2) 首都医科大学, 首都医科大学科研培育基金, PYZ2018052, 流行性乙型脑炎新型DNA疫苗pVAX1-SA14 M
E的长效保护作用及其机制的研究, 2019-01 至 2019-12, 5万元, 结题, 主持
(3) 首都医科大学, 首都医科大学科研培育基金, PYZ2017019, 登革热四价DNA疫苗的构建及免疫效果的研
究, 2018-01 至 2018-12, 5万元, 结题, 主持
代表性论著:
(1) Ningze Sun; Zhiwei Su; Xiaoyan Zheng ; Research progress of mosquito-borne virus mRNA vaccines, Molecular Therapy Methods & Clinical Development, DOI: 10.1016/j.omtm.2024.101398, 2024, 33(1): 101398
(2) Xiaoyan Zheng; Ran Wang; Chenghong Yin ; An untargeted metabolomics investigation in liver of flaviviruses-infected mice, Virology, DOI: 10.1016/j.virol.2023.03.008, 2023, 582: 12-22
(3) Zheng Xiaoyan, Wang Ran*. Metabolomic Analysis of Key Regulatory Metabolites in the Urine of Flavivirus-Infected Mice. J Trop Med. 2022 Jun 1;2022:4663735. doi: 10.1155/2022/4663735.
(4)Zheng Xiaoyan, Wang Fei, Wang Lei, Li Xiaoli, Li Jingjing, Huang Minjun, Zou Yang*. A Rare Case of Cysticercosis Involving the Whole Spinal Canal.Acta Parasitol. Acta Parasitol. 2022 Mar;67(1):569-572. doi: 10.1007/s11686-021-00486-1.
(5)Zheng Xiaoyan, Yu Xiaozheng, Wang Yan, Cui Min, Wang Ran*, Yin Chenghong*.Complete protection for mice conferred by a DNA vaccine based on the Japanese encephalitis virus P3 strain used to prepare the inactivated vaccine in China.Virol J,2020 Aug 24;17(1):126. doi: 10.1186/s12985-020-01400-3.
(6)Zheng Xiaoyan, Yu Xiaozheng, Wang Yan, Cui Min, Wang Ran*, Yin Chenghong*. Immune Responses and Protective Effects Against Japanese Encephalitis Induced by a DNA Vaccine Encoding the prM/E Proteins of the Attenuated SA14-14-2 Strain. Infect Genet Evol. 2020 Jun 30:104443. doi: 10.1016/j.meegid.2020.104443.
(7)Zheng Xiaoyan, Ma Xiao, Li Tingting, Shi Wanliang, Zhang Ying*. Effect of different drugs and drug combinations on killing stationary phase and biofilms recovered cells of bartonella henselae in vitro. BMC Microbiology, 2020, 20(1): 87.
(8) Zheng Xiaoyan; Chen Hui; Wang Ran; Fan Dongying; Feng Kaihao; Gao Na; An Jing ; Effective protection induced by
a monovalent DNA vaccine against dengue virus (DV) serotype 1 and abivalent DNA vaccine against DV1 and DV2 in mice,
Frontiers in Cellular and Infection Microbiology, 2017,7: 175
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