闫银坤，医学博士，副教授，副研究员，博士生导师，国家儿童医学中心、首都医科大学附属北京儿童医院慢病管理中心主任，北京市海外高层次人才、北京市科技新星。2015年毕业于北京协和医学院获流行病与卫生统计学博士学位，同年进入首都儿科研究所流行病学研究室工作，2017-2019年赴美国杜兰大学公共卫生与热带医学学院流行病系进行博士后研究，2020年1月进入首都医科大学附属北京儿童医院儿童慢病管理中心工作。研究方向为儿童肥胖代谢病防控。担任北京健康管理协会儿童健康管理分会主委、中华预防医学会儿童成人病(慢病)防治工作委员会委员、中国健康促进与教育协会肥胖防治分会常务委员、中国初级卫生保健基金会大数据统计及空间流行病学专业委员会常务委员、中国优生优育协会母婴心血管结构与代谢专业委员会委员、《中华高血压杂志》编委、《中国预防医学杂志》编委、《中国校医》杂志常务编委、《Pediatric Investigation》》编委。主持国家自然科学基金3项及国家科技重大专项课题1项，以第一/通讯作者发表论文40余篇，包括JACC、Circulation Research、JAMA Network Open等领域权威杂志。获北京市科学技术二等奖，申请软件著作权2项。 

1. 国家科技创新2030重大专项-课题，儿童肥胖防控运动干预，2023ZD0508505，2024.08-2028.08，课题负责人，255万元，在研

   国家自然科学基金面上项目，肠道阿克曼菌调节胆汁酸代谢激活TGR5信号通路在肥胖儿童NAFLD中的作用及机制研究，82473650，2025.01-2028.12，49万，课题负责人，在研

   北京市科技新星计划交叉课题，影响儿童非酒精性脂肪肝进展的关键菌群筛选及机制研究，20230484467，2023.11-2026.11，50万，课题负责人，在研

   首都医科大学优秀青年项目，心血管代谢疾病的生命周期流行病学，1220090117，2022.01-2024.12，100万元，课题负责人，结题

   国家自然科学基金面上项目，儿童不同部位脂肪蓄积对心血管亚临床损害的影响及其代谢机制的队列研究，82073572，2021.01-2024.12，55万，课题负责人，结题

   北京市科技新星计划项目，儿童局部脂肪对亚临床动脉粥样硬化的差异化影响及相关机制研究，Z201100006820008，2020.9-2023.8，40万，课题负责人，结题

   国家自然青年科学基金，儿童至成年肥胖指标的变化轨迹对慢性肾病的影响及相关机制研究，81803254, 2019.1-2021.12, 21万，课题负责人，结题

1.Qian Y, Kong Y, Wan N*, Yan Y*. Associations between body mass index in different childhood age periods and hyperuricemia in young adulthood: the China Health and Nutrition Survey cohort study. World journal of pediatrics, 2022.(Published Online)

2.Rao J#, Ye P#, Lu J, Chen B, Li N, Zhang H, Bo H, Chen X, Liu H, Zhang C, Wei H, Wu Q, Yan Y*, Li C*, Mi J*, China Child and Adolescent Hyperuricemia Study (CCAHS) Consortium. Prevalence and related factors of hyperuricaemia in Chinese children and adolescents: a pooled analysis of 11 population-based studies. Ann Med, 2022, 54(1), 1608-1615. 

3.Gao Y, Kong Y, Li S, Dong S, Huang X, Qi D, Zhang T, Yan Y*, Chen W. Intermediate Effects of Body Mass Index and C-Reactive Protein on the Serum Cotinine-Telomere Length Association. Frontiers in Aging Neuroscience. 2021;13: 827465.

4.Yan YK, Mi J*. Noncommunicable chronic disease prevention should start from childhood. Pediatr Investig. 2021;5(1):3-5.

5.Yan YK, Li S, Liu Y, Bazzano L, He J, Mi J, Chen W*.The impact of body weight trajectory from childhood on chronic inflammation in adulthood: The Bogalusa Heart Study. Pediatr Investig. 2021;5(1):21-27.

6.Dong HB#, Yan YK#, Liu JT#, Cheng H, Zhao XY, Shan XY, Huang GM, Mi J*. Reference centiles for evaluating total body fat development and fat distribution by dual-energy x-ray absorptiometry among children and adolescents aged 3-18 years. Clin Nutr. 2021;40(3):1289-1295. 

7.Yan Y, Li S, Bazzano L, Guo Y, Fernandez C, Mi J, Bazzano L, He J, Chen W. Life-course Cumulative Burden of Body Mass Index and Blood Pressure on Progression of Left Ventricular Mass and Geometry in Midlife: The Bogalusa Heart Study. Circulation Research. 2020,126:633–643. 

8.Dou Y#, Jiang J#, Yan Y#, Chen H, Zhang Y, Chen X, Wang Y, Cheng H, Zhao X, Hou D, Mi J, Yan W, China Child and Adolescent Cardiovascular Health (CCACH) Study Research Group. Waist-to-height ratio as a screening tool for cardiometabolic risk in children and adolescents: a nationwide cross-sectional study in China. BMJ Open. 2020,10:e037040.

9.Yan Y, Liu J, Zhao X, Cheng H, Huang G, Mi J, China Child and Adolescent Cardiovascular Health (CCACH) Study Research Group. Abdominal Visceral and Subcutaneous Adipose Tissues in Association with Cardiometabolic Risk in Children and Adolescents: The China Child and Adolescent Cardiovascular Health (CCACH) study. BMJ Open Diab Res Care. 2019, 7:e000824.

10.Yan Y, Bazzano L, Juonala M, Raitakari O, Viikari J, Prineas R, Dwyer T, Sinaiko A, Burns T, Daniels S, Woo J, Khoury P, Urbina E, Jacobs D, Hu T, Steinberger J, Venn A, Wei Chen. Long-1. Gao C, Meng X, Liu W, Qi Q, Yan Y*. Identification of sensitive periods of weight status transition over the lifespan in Chinese population. BMC Medicine 2024, 22:507.

2. Ye P#, Gao L#, Xia Z, Peng L, Shi X, Ma J, Dong Y, Dai D, Yang Q, Chen X, Fan X, Wan N, Zhang J, Li B, Zhou L, Wu G, Yang L, Li X*, Yan Y*, He Y*. Association between non-alcoholic fatty liver disease and metabolic abnormalities in children with different weight statuses. Public Health. 2024, 235:160-166.

3. Rao J#, Yan Y#, Cheng H, Hou D, Zhao X, Shan X, Mi J*. Uric acid mediated the relationship between obesity and hypertension in children and adolescents: A population‑based cohort study. Nutr Metab Cardiovasc Dis, 2024 Jan;34(1):214-222.

4. Qian Y, Kong Y, Wan N*, Yan Y*. Body mass index in different childhood age periods associated with cardiometabolic disorders in young adulthood. Obesity, 2023;31:2365–237

5. Xiaoran Yu, Jie Dong*, Shiting Xiang , Xun L , Yongquan Qin, Shaolun Zhu, Jie Zheng, Yinkun Yan*, Jie Mi*.  Association of intestinal microbiota and its metabolite markers with excess weight in Chinese children and adolescents. Pediatric Obesity. 2023, 18(6): e13019.

6. Yinkun Yan# , Xuan Wang#, Shengxu Li, Yang Liu, Dianjian Sun, Yajun Guo, Lydia Bazzano, Jiang He, Tao Zhang*, Wei Chen. Bidirectional Temporal Relationships between Uric Acid and Insulin and Their Joint Impact on Incident Diabetes. Nutrition, Metabolism and Cardiovascular Diseases. 2023,33(2):331-339.

7. Zhang T, Fan B, Li S, Wang X, Kong Y, Bazzano L, He J, Chen W, Yan Y*. Long-Term Adiposity and Midlife Carotid Intima-Media Thickness Are Linked Partly Through Intermediate Risk Factors. Hypertension. 2023, 80(1):160-168.

8. Yinkun Yan*, Shengxu Li, Yang Liu, Yajun Guo, Camilo Fernandez, Lydia Bazzano, Jiang He, Wei Chen. Associations Between Life-Course Lipid Trajectories and Subclinical Atherosclerosis in Midlife. JAMA Network Open. 2022, 5(10):e2234862.

9. Qian Y, Kong Y, Wan N*, Yan Y*. Associations between body mass index in different childhood age periods and hyperuricemia in young adulthood: the China Health and Nutrition Survey cohort study. World journal of pediatrics. 2022, 18(10):680-686.

10. Rao J#, Ye P#, Lu J, Chen B, Li N, Zhang H, Bo H, Chen X, Liu H, Zhang C, Wei H, Wu Q, Yan Y*, Li C*, Mi J*, China Child and Adolescent Hyperuricemia Study (CCAHS) Consortium. Prevalence and related factors of hyperuricaemia in Chinese children and adolescents: a pooled analysis of 11 population-based studies. Ann Med, 2022, 54(1): 1608-1615.

11. Gao X, Kong Y, Li S, Dong S, Huang X, Qi D, Zhang T, Yan Y*, Chen W. Intermediate Effects of Body Mass Index and C-Reactive Protein on the Serum Cotinine-Telomere Length Association. Frontiers in Aging Neuroscience. 2021;13: 827465.

12. Yan YK, Mi J*. Noncommunicable chronic disease prevention should start from childhood. Pediatr Investig. 2021;5(1):3-5.

13. Yan YK, Li S, Liu Y, Bazzano L, He J, Mi J, Chen W*.The impact of body weight trajectory from childhood on chronic inflammation in adulthood: The Bogalusa Heart Study. Pediatr Investig. 2021;5(1):21-27.

14. Dong HB#, Yan YK#, Liu JT#, Cheng H, Zhao XY, Shan XY, Huang GM, Mi J*. Reference centiles for evaluating total body fat development and fat distribution by dual-energy x-ray absorptiometry among children and adolescents aged 3-18 years. Clin Nutr. 2021;40(3):1289-1295.

15. Yan Y, Li S, Bazzano L, Guo Y, Fernandez C, Mi J, Bazzano L, He J, Chen W. Life-course Cumulative Burden of Body Mass Index and Blood Pressure on Progression of Left Ventricular Mass and Geometry in Midlife: The Bogalusa Heart Study. Circulation Research. 2020,126:633–643. DOI: 10.1161/CIRCRESAHA.119.316045

16. Dou Y#, Jiang J#, Yan Y#, Chen H, Zhang Y, Chen X, Wang Y, Cheng H, Zhao X, Hou D, Mi J, Yan W, China Child and Adolescent Cardiovascular Health (CCACH) Study Research Group. Waist-to-height ratio as a screening tool for cardiometabolic risk in children and adolescents: a nationwide cross-sectional study in China. BMJ Open. 2020,10:e037040.(IF=2.692)

17. Yan Y, Liu J, Zhao X, Cheng H, Huang G, Mi J, China Child and Adolescent Cardiovascular Health (CCACH) Study Research Group. Abdominal Visceral and Subcutaneous Adipose Tissues in Association with Cardiometabolic Risk in Children and Adolescents: The China Child and Adolescent Cardiovascular Health (CCACH) study. BMJ Open Diab Res Care. 2019, 7:e000824.(IF=5.067)

18. Yan Y, Bazzano L, Juonala M, Raitakari O, Viikari J, Prineas R, Dwyer T, Sinaiko A, Burns T, Daniels S, Woo J, Khoury P, Urbina E, Jacobs D, Hu T, Steinberger J, Venn A, Wei Chen. Long-Term Burden of Increased Body Mass Index from Childhood on Adult Dyslipidemia: The i3C Consortium Study. J. Clin. Med. 2019, 8(10): 1725. (IF=5.688)

19. Yan Y, Liu J, Zhao X, Cheng H, Huang G, Mi J, China Child and Adolescent Cardiovascular Health (CCACH) Study Research Group. Regional Adipose Compartments Confer Different Cardiometabolic Risk in Children and Adolescents: The China Child and Adolescent Cardiovascular Health Study. Mayo Clin Proc.2019,94(10):1974-1982.

20. Yan Y, Li S, Liu Y, Bazzano L, He J, Mi J, Chen W. Temporal relationship between inflammation and insulin resistance and their joint effect on hyperglycemia: the Bogalusa Heart Study. Cardiovasc Diabetol.2019,18(1):109. (IF=9.951)

21. Yan Y, Liu J, Zhao X, Cheng H, Huang G, Hou D, Mi J. China Child and Adolescent Cardiovascular Health (CCACH) collaboration group. Cardiovascular health in urban Chinese children and adolescents. Ann Med.2019,51(1):88-96.

22. Tang J#, Yan Y#, Li J, Yang B, Zhao X, Wan Y, Mi J, Li D. Relationship between erythrocyte phospholipid fatty acid composition and obesity in children and adolescents. Journal of Clinical Lipidology.2019, 13(1):70-79. (IF= 4.766)

23. Yan Y, Zhang T, Li S, Liu Y, Bazzano L, He J, Mi J, Chen W. Black-White Difference in the Impact of Long-term Blood Pressure from Childhood on Adult Renal Function: the Bogalusa Heart Study. American Journal of Hypertension, 2018, 31(12): 1300-1306.

24. Hou DQ#, Yan Y#, Liu JT, Zhao XY, Cheng H, Mi J. Childhood pulse pressure predicts subclinical vascular damage in adulthood: the Beijing Blood Pressure Cohort Study. Journal of Hypertension. 2018, 36(8):1656-1662.

25. Yan Y#, Liu J#, Wang L, Hou DQ, Zhao XY, Cheng H, Mi J. Independent influences of excessive body weight and elevated blood pressure from childhood on left ventricular geometric remodeling in adulthood. International Journal of Cardiology. 2017, 243: 492–496.

26. Yan Y, Hou D, Zhao XY, Liu JT, Cheng H, Wang YF, Mi J. Childhood Adiposity and Nonalcoholic Fatty Liver Disease in Adulthood. Pediatrics. 2017, 139(4):e20162738. DOI:10.1542/peds.2016-2738.

27. Yan Y, Hou D, Liu J, Zhao X, Cheng H, Xi B, Mi J. Childhood body mass index and blood pressure in prediction of subclinical vascular damage in adulthood: Beijing blood pressure cohort. Journal of Hypertension. 2017, 35:47–54.

28. Yan Y, Hou D, Liang Y, Zhao X, Hu Y, Liu J, Cheng H, Yang P, Shan X, Xi B, Mi J. Tracking body mass index from childhood to adulthood for subclinical Cardiovascular Diseases at Adulthood. Journal of the American College of Cardiology. 2016, 67(8):1006-1007. DOI: 10.1016/j.jacc.2015.12.013.