1. 国家自然科学基金（面上项目）

课题名称：TMEM30A/STAT通路对脑卒中后缺血半暗带组织神经保护中的作用及相关机制研究

课题编号：82071466

2.国家自然科学基金（面上项目）

课题名称：血管再通基础上治疗性低温的神经保护作用及“help-me”信号相关机制研究

课题编号：81871022

3.国家自然科学基金（青年项目）

课题名称：区域性低温联合NAMPT治疗大鼠缺血性卒中的效果及神经保护机制分析

课题编号：81500997

4.北京医管局青苗项目：

课题名称：局部选择性低温治疗恒河猴急性缺血性脑卒中的疗效分析

课题编号：SML20150802

1       Wu D, Chen J, Wu L, Lee H, ShiJ, Zhang M, Ma Y, He X, Zhu Z, Yan F, Wu C, Duan Y, Fu Y, Li S, Zhi X, Zhang X,Li S, Ding Y, Ji X*. A clinically relevant model of focal emboliccerebral ischemia by thrombus and thrombolysis in rhesus monkeys. Nat Protoc.2022 Jun 27. doi: 10.1038/s41596-022-00707-5.

2       Zhao H#, Zhao J#, Wu D#, Sun Z#, Hua Y, ZhengM, Liu Y, Yang Q, Huang X, Li Y, Piao Y, Wang Y, Lam SM, Xu H, Shui G, Wang Y,Yao H, Lai L, Du Z, Mi J*, Liu E*, Ji X*, Zhang YQ*. Dogs lackingApolipoprotein E show advanced atherosclerosis leading to apparent clinicalcomplications. Sci China Life Sci. 2022;65(7):1342-1356.

3       Wu D, Chen J, Zhang X, IlaganR, Ding Y, Ji X. Selective therapeutic cooling: To maximize benefits andminimize side effects related to hypothermia. J Cereb Blood Flow Metab. 2022;42(1):213-215.

4       Wang L, Wu L, Duan Y, Xu S, Yang Y, Yin J, Lang Y, Gao Z, WuC, Lv Z, Shi J, Wu D*, Ji X*. Phenotype Shifting inAstrocytes Account for Benefits of Intra-Arterial Selective Cooling Infusion inHypertensive Rats of Ischemic Stroke. Neurotherapeutics. 2022 Jan;19(1):386-398.

5       Wu L#, Wu D#, Chen J, Chen C, Yao T, He X, Ma Y, Zhi X, Liu R, Ji X*.Intranasal salvinorin A improves neurological outcome in rhesus monkey ischemicstroke model using autologous blood clot. J Cereb Blood Flow Metab.  2021,41:723-730.

6       Fang Z#, Wu D#, Deng J#, Ji X*, Dong H*, Xiong L*. A MD2-perturbing peptide hastherapeutic effects in rodent and rhesus monkey models of stroke. Sci. Trans.Med. 2021, 13(597):eabb6716.

7       Wu D#, Fu Y#, Wu L#, Huber M, Chen J, Yao T, Zhang M, WuC, Song M, He X, Li S, Zhang Y, Li S, Ding Y, Ji X*. Reperfusion plus SelectiveIntra-arterial Cooling (SI-AC) Improve Recovery in a Nonhuman Primate Model ofStroke. Neurotherapeutics. 2020, 17:1931-1939.  

8       Wu D, Wu L, Chen J, He X, Li S, Ding Y, Ji X. Primate version ofmodified Rankin scale for classifying dysfunction in rhesus monkeys. Stroke,2020,51:1620-1623.

9       Wu D#, Chen J#, HussainM, Wu D, Chen J, Hussain M, Wu L, Shi J, Wu C, Ma Y, Zhang M, Yang Q, Fu Y,Duan Y, Ma C, Yan F, Zhu Z, He X, Yao T, Song M, Zhi X, Wang C, Cai L, Li C, LiS, Zhang Y, Ding Y, Ji X*. Selective intra-arterial brain cooling improveslong-term outcomes in a non-human primate model of embolic stroke: efficacydepending on reperfusion status. J Cereb Blood Flow Metab, 2020,40(7):1415-1426.

10    Gao Y#, Wu D#, Liu D#, Huber M, Chen J, Wang X, Lv K, He X, Yang H, Ren C, Ding Y,Ji X*, Zhang X*. Novel Acute Retinal Artery Ischemia and Reperfusion Model inNonhuman Primates. Stroke. 2020;51:2568-2572.

11    Wu D#, Zhi X#, Duan Y, et al. Inflammatorycytokines are involved in dihydrocapsaicin (DHC) and regional cooling infusion(RCI)-induced neuroprotection in ischemic rat. Brain Res. 2019;1710:173-180.

12    Wu D, Chandra A, Chen J, DingY, Ji X. Endovascular Ischemic Stroke Models in Nonhuman Primates. Neurotherapeutics.2018;15(1):146-155.