已培养硕士毕业生5人，联合培养博士毕业生1人，其中获校级优秀毕业生称号4人次，获北京市优秀毕业生称号1人次。毕业生就业于国家药监局、北京大学肿瘤医院、北京博爱医院等单位，或至北京协和医学院等高校升读博士学位。

【1】国家自然科学基金面上项目, 基于PPARγ受体研究益智仁促血管新生缓解膀胱过度活动症的分子机制, 2026.01至2029.12, 48万, 在研, 主持.

【2】国家自然科学基金青年科学基金, 81703796, 葛根对选择性毒蕈碱M3受体拮抗剂治疗膀胱过度活动症的增效减毒机制, 2018.01 至 2020.12, 20万,  结题, 主持.

【3】北京市自然科学基金面上项目, 7182159, 基于毒蕈碱M3受体的大豆黄卷抑制逼尿肌过度活跃的药效物质基础及药理机制研究, 2018.01 至 2020.12, 20万, 结题, 主持.

重要奖项

[1] 基于临床的中药性效整合模式构建与转化应用. 2024年中华中医药学会科技奖一等奖(12/15). 

[2] 药用鼠尾草活性成分代谢特征与药理作用的系统研究. 2021年中华医学科技奖三等奖(2/8).

[3] 膀胱过度活动症治疗中药的分子机制研究. 2025年首都医科大学自然科学奖三等奖(1/1).

近三年代表性论文

[1] Xinyi Tong#, Yining Qiang#, Mingchang Cheng, Yan Tie, Zhihui Sun, Yi Ma, Yushan Wu, Liping Xu, Pingxiang Xu, Xiaorong Li, Ming Xue, Xuelin Zhou*. Multi-Omics analysis revealed the therapeutic mechanisms of Gegen (Puerariae lobatae Radix) water extract against ischemia-induced bladder overactivity through the inhibition of epoxide hydrolase 2. Phytotherapy research. 2025, 39(8): 3813-3828.

[2] Jiawei Wang#, Qichao Hu#, Jianying Wang#, Liwei Lang, Shizhang Wei, Haotian Li, Manyi Jing, Xiao Ma***, Yanling Zhao**, Xuelin Zhou*. Role of gut microbiota and fecal metabolites in the protective effect of soybean pulp-rich diet against estrogen-induced cholestasis in rats. Current Research in Food Science. 2025, 10(6):100990.

[3] Mingchang Cheng, Yining Qiang, Yushan Wu, Xinyi Tong, Yan Tie, Zhihui Sun, Shenghan Guan, Liping Xu, Pingxiang Xu, Xiaorong Li, Ming Xue, Xuelin Zhou*. Multi-omic approaches provide insights into the molecular mechanisms of Sojae semen germinatum water extract against overactive bladder. Food Research International. 2024, 175: 113746.  

[4] Yan Tie, Zhihui Sun, Xinyi Tong, Mingchang Cheng, Yushan Wu, Zhilong Shi, Pingxiang Xu, Ming Xue, Liping Xu**, Xuelin Zhou*. Multi-Omic analysis revealed the therapeutic mechanisms of Alpinia Oxyphylla Fructus water extract against bladder overactivity in spontaneously hypertensive rats. Phytomedicine, 2024, 123: 155154.

[5] Yi Wu#, Yi Ma#, Qiang Li, Jing Li, Di Zhang, Yuxin Zhang, Yue Li, Xiaorong Li, Pingxiang Xu, Lu Bai, Xuelin Zhou*, Ming Xue*. Multi-omics analysis reveals phenylalanine enhance mitochondrial function and hypoxic endurance via LKB1/AMPK activation. Journal of Translational Medicine. 2024, 22: 920.

[6] Qiang Li, Zhengchao Xia, Yi Wu, Yi Ma, Di Zhang, Sihan Wang, Jingxin Fan, Pingxiang Xu, Xiaorong Li, Lu Bai, Xuelin Zhou**, Ming Xue*. Lysophospholipid acyltransferase-mediated formation of saturated glycerophospholipids maintained cell membrane integrity for hypoxic adaptation. FEBS Journal. 2024, 291(14): 3191-3210.

[7] Zhihui Sun, Yan Tie, Xinyi Tong, Mingchang Cheng, Yushan Wu, Pingxiang Xu, Ming Xue, Liping Xu**, Xuelin Zhou*. Multi-omics approaches revealed the therapeutic mechanisms of Suo-Quan-Wan for treating overactive bladder in spontaneously hypertensive rats. Journal of Ethnopharmacology. 2024, 318(Pt B): 117066.

[8] Yan Tie#, Jihan Liu#, Yushan Wu#, Yining Qiang, Ge’Er Cai’Li, Pingxiang Xu, Ming Xue, Liping Xu, Xiaorong Li*, Xuelin Zhou*. A Dataset for Constructing the Network Pharmacology of Overactive Bladder and Its Application to Reveal the Potential Therapeutic Targets of Rhyncholphylline. Pharmaceuticals. 2024, 17, 1253.