（1）国家自然科学基金面上项目，82174062，基于Pulsed-dc-ESI-MS的细胞药动学和PfATP6酶活抑制的SCIAaL遏制疟原虫耐药机制研究，2022/01-2025/12，55万元，主持，进行中.

（2）国家自然科学基金面上项目，81573682，青蒿内含增效组分协同促青蒿素抗疟活性的机制研究，2016/01-2019/12，57万元，主持，已结题.

（3）首都中医药研究专项面上项目，1150170204/15ZY06，青蒿素及青蒿内含增强子组的体内外代谢机制研究，2015.01-2016.12，4万元，主持，已结题.

（4）横向课题，水蛭配方颗粒质量标准研究，广东一方制药有限公司，2020/11-2022/11，14.5万元，主持，已结题.

1. Fu C, Yu P, Wang M, Qiu F*. Phytochemical analysis and geographic assessment of flavonoids, coumarins and sesquiterpenes in Artemisia annua L. based on HPLC-DAD quantification and LC-ESI-QTOF-MS/MS confirmation. Food Chem. 2020; 312: 126070.

2. Fu C, Zhang K, Wang M, Qiu F*. Casticin and chrysosplenol D from Artemisia annua L. induce apoptosis by inhibiting topoisomerase IIa in human non-small-cell lung cancer cells. Phytomedicine. 2022, 100: 154095.

3. Fu C, Zhang K, Wang M, Qiu F*. Multi-component pharmacokinetics assessment of Artemisia annua L. in rats based on LC-ESI-MS/MS quantification combined with molecular docking. Arab J Chem. 2022, 15: 104254.

4. Zhang P, Ma H, Lin X, Qiu F*. Simultaneous quantification and rat pharmacokinetics of formononetin-7-O-β-d-glucosideand its metabolite formononetin by high-performance liquidchromatography-tandem mass spectrometry. J Sep Sci. 2020; 43 (15): 2996-3005.

5. Qu H, Zhang K, Fu C, Qiu F*. Simultaneous quantification and pharmacokinetic evaluation of roflumilast and its N-oxide in cynomolgus monkey plasma by LC-MS/MS method. Biomed Chromatogr. 2021; 35(2): e4973.

6. Fu C, Shi H, Chen H, Zhang K, Wang M*, Qiu F*. Oral bioavailability comparison of artemisinin, deoxyartemisinin, and 10-deoxoartemisinin based on computer simulations and pharmacokinetics in rats. ACS Omega. 2020; 6 (1): 889-899.

7. Lian Z#, Chen H#, Liu K, Jia Q, Qiu F*, Cheng Y*.Improved stability of a stable crystal form C of 6S-5-methyltetrahydrofolate calciumsalt, method development and validation of an LC-MS/MS method for rat pharmacokinetic comparison. Molecules. 2021; 26 (19): 6011.

8. Zhang K#, Zhang D#, Ge Z*, Qiu F*. Development and validation of an LC-MS/MS method for the quantification of free and total doxorubicin in human plasma and its clinical application for a novel doxorubicin hydrochloride liposome injection in Chinese patients with breast cancer. Acta Chromatographica. 2023. DOI:https://doi.org/10.1556/1326.2023.01129.

9. Chen H#, Aili R#, Wang M, Qiu F*. Transformationprofiles of the isoflavones in germinated soybean based on UPLC-DAD quantification and LC-QTOF-MS/MS confirmation. Food Chem X. 2024; 22: 101413.

10. Liu Y, Tao C, Ma H, Qiu F*. Differential comparison of chemical compositions between two Wutou Decoctions based on ultra-high performance liquid chromatography coupled with quadrupole time−of−flight tandem mass spectrometry combined with chemometric analysis. J Sep Sci. 2024; 47 (23): e70047.