首都医科大学附属北京潞河医院卒中治疗与转化中心（SITC）团队，包括神经介入、静脉溶栓、神经重症、卒中护理以及临床和基础研究团队，致力于区域性卒中预防、卒中急性期救治、血管内介入诊疗及神经危重症患者管理等方面工作。SITC团队坚持以病人为中心，基础研究服务临床的宗旨，形成了以缺血性脑卒中救治为主导，脑心同治、康复、眩晕、癫痫、神经免疫疾病和神经变性病多亚专业共同建设的研究方向。团队负责人耿晓坤，入选北京市科技新星，指导专家美国韦恩州立大学丁玉川教授，建立了由临床医生+基础研究员+研究生等30余人的人才梯队，其中博士学位≥15人，北京市海聚人才、北京市科技新星各1人，北京市优秀人才2人，通州区运河计划8人，多次获得通州区科技进步奖、首都医科大学自然科学奖。团队主持国自然15项，北京市级课题9项，区校级课题30余项。发表SCI论文110余篇，影响因子＞300，获批专利10余项，并实现临床转化；团队10余人次受邀美国国际卒中大会宣讲。

1.国自然青年项目，2024.01-2026.12，精神压力通过组蛋白H3K18乳酸化修饰激活ATF4-DRP1诱导神经元线粒体裂变加重缺血损伤机制

2.国自然青年项目，2024.01-2026.12，缺血性脑卒中后肝源性神经元铜死亡及肝脏亚低温的远程神经保护机制

3.国自然面上项目，2023.01-2026.12，HDAC9靶向溶酶体蛋白调节巨噬细胞吞噬功能影响缺血性卒中后认知障碍的机制研究；

4.国自然青年项目，2022.01-2024.12，RBM3冷休克通路促进神经重塑的相关机制及其作为缺血性脑卒中后低温治疗新靶点的研究；

5.国自然青年项目，2022.01-2024.12，IL-17A通过PKCζ-ERK-ROS通路调节PAD4影响缺血性卒中NETs形成的机制研究；

6.国自然面上项目，2021.01-2024.12，常压高浓度氧联合OGA抑制剂驱动NeuroD1糖基化正反馈信号稳定脑缺血神经环路的机制研究；

7.国自然青年项目，2021.01-2023.12，短时间歇运动训练促进卒中后运动功能恢复及PLD2/PA/mTOR传导通路的实验研究；

8.国自然青年项目，2021.01-2023.12，早期且再灌前药物低温对缺血性脑卒中的神经保护作用及p38-ELAVL1-HIF-1α信号通路；

9.国自然面上项目，2019.01-2022.12，超早期康复锻炼通过HIF-1α调控PCK促进不完全糖异生途径加剧脑卒中损伤的机制研究；

10.国自然青年项目，2019.01-2021.12，过早期康复锻炼加剧脑缺血后ROS介导的内质网应激损伤的机制研究；

11.国自然青年项目，2018.01-2020.12，PM2.5对脑动脉粥样硬化的影响及NADPH氧化酶参与调控的分子机制研究；

12.国自然青年项目，2018.01-2020.12，LncRNA Gm15628介导的单核细胞来源巨噬细胞极化状态在缺血性卒中脑损伤中的作用研究；

13.国自然面上项目，2017.01-2020.12，褪黑素保护脑缺血白质损伤相关机制研究；

14.国自然面上项目，2016.01-2019.12，二十六碳六烯酸（DHA）促进缺血性卒中长期神经功能恢复及其对白质损伤保护机制研究；

15.国自然青年项目，2016.01-2018.12，常压氧（NBO）联合乙醇降低脑缺血后氧化应激损伤机制研究；

1.        国家自然科学基金面上项目，HDAC9靶向溶酶体蛋白调节巨噬细胞吞噬功能影响缺血性卒中后认知障碍的机制研究，2023.01-2026.12，主持。

2.        国家自然科学基金面上项目，常压高浓度氧联合OGA抑制剂驱动NeuroD1糖基化正反馈信号稳定脑缺血神经环路的机制研究，2021.01-2024.12，主持。

3.        国家自然科学基金面上项目，超早期康复锻炼通过HIF-1α调控PCK促进不完全糖异生途径加剧脑卒中损伤的机制研究，2019.01-2022.12，主持。

4.        首都临床特色项目，Z221100007422085，脾脏亚低温联合脑动脉机械取栓治疗急性缺血性脑卒中的神经保护作用研究，2022.11-2025.11，主持。

5.        通州区发展专项重点项目，巨噬细胞计划特性的微流控定量检测新方法及其对缺血性脑卒中机械取栓在灌注损伤预测价值，2023.01-2024.12，主持。

1.      Guo S, Wehbe  A, Syed S, Wills  M, Guan  L, Lv S, Li  F, Geng X*, Ding Y*. Cerebral Glucose Metabolism and Potential Effectson Endoplasmic Reticulum Stress in Stroke. Aging Dis. 2023 Apr 1;14(2):450-467.IF 10.0

2.      Lv S, Geng X*, Yun HJ, Ding Y. Phenothiazinesreduced autophagy in ischemic stroke through endoplasmic reticulum (ER)stress-associated PERK-eIF2α pathway. Exp Neurol. 2023 Sep 9;369:114524. IF 5.6

3.      Duan H, Yun HJ, Rajah GB, Che F, Wang Y,Liu J, Tong Y, Cheng Z, Cai L, Geng X*, Ding Y*. Large vessel occlusion strokeoutcomes in diabetic vs. non-diabetic patients with acute stress hyperglycemia.Front Neurosci. 2023 Jan 27;17:1073924.

4.      Wang Y, Jun Yun H, Ding Y, Du H, Geng X*. Montelukastsodium protects against focal cerebral ischemic injury by regulatinginflammatory reaction via promoting microglia polarization. Brain Res. 2023 Oct15;1817:148498.

5.      Li F, GengX*, Ilagan R, Bai S, Chen, Y, Ding Y*. Exercise Postconditioning ReducesIschemic Injury Via Suppression of Cerebral Gluconeogenesis in Rats. BrainBehav. 2023;13(1):e2805. IF 2.6

6.      Duan H, Cheng Z, Yun HJ, Cai L, Tong Y,Han Z, Geng X*, Ding Y*. SerumBilirubin Associated with Stroke Severity and Prognosis: Preliminary Findingson Liver Function after Acute Ischemic Stroke. Neurol Res. 2023;45(1):62-69. IF2.5

7.      Zhu Y, Haddad Y, Yun HJ, Geng X*, Ding Y*.Induced Inflammatory and Oxidative Markers in Cerebral Microvasculature byMentally Depressive Stress. Mediators Inflamm. 2023 Feb 18;2023:4206316.

8.      Duan H, Geng X*, Ding Y. Hepatic responsesfollowing acute ischemic stroke: A clinical research update. Brain Circ. 2023Jun 30;9(2):57-60.

9.      Wang Q, Wehbe A, Wills M, Li F, Geng X*,Ding Y. The Key Role of Initiation Timing on Stroke Rehabilitation by RemoteIschemic Conditioning with Exercise (RICE). Neurol Res. 2023 Apr;45(4):334-345.

10.  Wang Q, Kohls W, Wills M, Li F, Pang Q,Geng X*, Ding Y*. A novel stroke rehabilitation strategy and underlying stressgranule regulations through inhibition of NLRP3 inflammasome activation. CNSNeurosci Ther. 2023 Aug 15. doi: 10.1111/cns.14405. IF 7.6

11.  Cheng Z, Ding Y, Rajah GB, Gao J, Li F, MaL, Geng X*. Vertebrobasilar artery cooling infusion in acute ischemic strokefor posterior circulation following thrombectomy: Rationale, design andprotocol for a prospective randomized controlled trial. Front Neurosci. 2023Apr 11;17:1149767.

12.  Li Y, Li X, Geng X*, Zhao H*. The IL-2A receptor pathway and its role inlymphocyte differentiation and function. Cytokine Growth Factor Rev.2022;67:66-79. IF 17.6

13.  Guo S, Mangal R, Dandu C, Geng X*, Ding Y*. Role of Forkhead BoxProtein O1 (FoxO1) in Stroke: A Literature Review. Aging Dis.2022;13(2):521-533. IF 10.0

14.  Guan L, Lee H, Geng X*, Li F, Shen J, Ji Y, Peng C, Du H, Ding Y*. NeuroprotectiveEffects of Pharmacological Hypothermia on Hyperglycolysis and Gluconeogenesisin Rats after Ischemic Stroke. Biomolecules. 2022;12(6):851. IF 6.1

15.  Guo S, Li F, Wills M, Yip J, Peng C, Geng X*, Ding Y*. Chlorpromazine andPromethazine (C+P) reduces brain injury after ischemic stroke through thePKC-δ/NOX/MnSOD pathway. Mediators Inflamm. 2022;2022:6886752. IF 4.6

16.  Cheng Z, Gao J, Rajah GB, Geng X*, Ding Y*. Adjuvant high-flownormobaric oxygen after mechanical thrombectomy for posterior circulation stroke:A randomized clinical trial. J Neurol Sci. 2022;441:120350. IF 4.6

17.  Wang X, Wehbe A, Kaura S, Chaudhry N, Geng X*, Ding Y*. Updates on SelectiveBrain Hypothermia: Studies From Bench Work to Clinical Trials. Front Neurol.2022;13:899547. IF 4.1

18.  Ji Q, Dong H*, Lee H, Liu Z, Tong Y, ElkinK, Haddad Y, Geng X*, Ding Y. ClinicalCharacteristics and Outcomes of Multiple Sclerosis and Neuromyelitis OpticaSpectrum Disorder With Brainstem Lesions as Heralding Prodrome. Front Neurol.2022;13:836337. IF 4.1

19.  Gao J, Cheng Z, Jiang S, Wills M, Wehbe A,Rajah GB, Geng X*, Ding Y*. ArterialGlyceryl Trinitrate in Acute Ischemic Stroke after Thrombectomy forNeuroprotection (AGAIN): Rationale, design and protocol for a prospectiverandomized controlled trial. BMC Geriatr 2022;22(1):804. IF 4.1

20.  Ji Q, Wang X, Zhao W, Wills M, Yun HJ, TongY, Cai L, Geng X*, Ding Y*. Effectsof remote ischemic conditioning on sleep complaints in Parkinson'sdisease-rationale, design, and protocol for a randomized controlled study.Front Neurol. 2022;13:932199. IF 4.1

21.  Tong Y, Lee H, Kohls W, Han Z, Duan H,Cheng Z, Li F, Gao J, Geng X*, DingY*. Remote Ischemic Conditioning (RIC) with Exercise (RICE) is Safe andFeasible for Acute Ischemic Stroke (AIS) Patients. Front Neurol.2022;13:981498. IF 4.1

22.  Cheng Z, Rajah GB, Gao J, Geng X*, Ding Y*. Passing ExtracranialArtery Occlusion by Intermediate Catheter With Expanding Microballoon (PEACE):A Novel Endovascular Therapy in Acute Tandem Occlusion Stroke. J Endovasc Ther.2022;29(5):790-797. IF 3.1

23.  Cai L, Yang J, Cosky E, Xin R, Geng X*, Ding Y. Enhanced CerebralMicrobleeds by Long-Term Air Pollution Exposure in Spontaneously HypertensiveRats. Neurol Res. 2022;44(3):196-205. IF 2.5

24.  Zhu Y, Geng X*, Stone C, Guo S, Syed S, Ding Y. Forkhead Box 1(FoxO1)mediates psychological stress-induced neuroinflammation. Neurol Res.2022;44(6):483-495. IF 2.5

25.  Fan H, Feng J, Wills M, Wang L, Chen X, Geng X*, Ding Y*. White MatterHyperintensities (WMH) and clinical outcome after vestibular neuritis. NeurolRes. 2022;44(7):622-629. IF 2.5

26.  Wang Q, Wehbe A, Wills M, Li F, Geng X*, Ding Y. The Key Role ofInitiation Timing on Stroke Rehabilitation by Remote Ischemic Conditioning withExercise (RICE). Neurol Res. 2022:1-12. IF 2.5

27.  Li F#, Gao J#, Kohls W, Geng X*, Ding Y. Perspectives on beneftof early and prereperfusion hypothermia by pharmacological approach in stroke.Brain circ. 2022;8(2):69-75. IF 1.7

28.  Guo, L, Yun H, Tan X, Geng X*, Ding Y. A case of unilateral recurrent cerebral corticalencephalitis with anti‑myelinoligodendrocyte glycoprotein antibodies. Brain circ. 2022;8(2):102-107. IF 1.7

29.  Ding, Y, DeGracia  D, GengX*, Ding Y. Perspectives on Effect ofSpleen in Ischemic Stroke.  Brain circ.2022;8(3):117-120. IF 1.7

30.  Gao J, Wehbe A, Li F, Chaudhry N, Peng C, Geng X*, Ding Y. Reperfusion andreperfusion injury after ischemic stroke. Environmental Dis. 2022;7(2):33-39.

31.   Wang Y,Haddad Y, Patelc R, Geng X*,Du H, Ding Y*. Factors Influencing the Outcome of Cardiogenic Cerebral EmbolismA Literature Review. Neurol Res, 2022;44(3):187-195. IF 2.5

32.  Guo S, Geng X*, Lee H, Ding Y*. Phenothiazine InhibitsNeuroinflammation and Inflammasome Activation Independent of Hypothermia AfterIschemic Stroke. Mol Neurobiol. 2021;58(12):6136-6152. IF 5.7

33.  Cheng Z, Rajah GB, Gao J, Geng X*, Ding Y*. PassingExtracranial Artery Occlusion by Intermediate Catheter With ExpandingMicroballoon (PEACE): A Novel Endovascular Therapy in Acute Tandem OcclusionStroke. J Endovasc Ther. 2021:15266028211064818. IF 3.1

34.  Li F, GengX*, Lee H, Wills M, Ding Y*. Neuroprotective effects of exercisepostconditioning after stroke via SIRT1 mediated suppression of endoplasmicreticulum (ER) stress. Front Cell Neurosci.2021;15:598230. IF 6.1

35.  Han Y, Geng X*, Lee H, Li F, Ding Y*. Neuroprotective Effects ofEarly Hypothermia Induced by Phenothiazines and DHC in Ischemic Stroke. Evid Based Complement Alternat Med. 2021:1207092.IF 2.6

36.  Cheng Z, Geng X*, Tong Y, Dornbos D 3rd, Hussain M, Rajah GB, Gao J,Ma L, Li F, Du H, Fisher M, Ding Y*. Adjuvant high flow normobaric oxygen aftermechanical thrombectomy for anterior circulation stroke: a randomized clinicaltrial. Neurotherapeutics. 2021:18(2):1188-1197.. IF 6.1

37.  Geng X#*,Shen J#, Li F, Yip J, Guan L, Rajah G, Peng C, DeGracia D, Ding Y*.Phosphoenolpyruvate Carboxykinase (PCK) in the Brain Gluconeogenic PathwayContributes to Oxidative and Lactic Injury after Stroke. Mol Neurobiol.2021;58(5):2309-2321. IF 5.7

38.  Cheng Z, Li F, Stone C, Elkin K, Peng C,Bardhi R, Geng X*, Ding Y.Normobaric oxygen therapy atenuates hyperglycolysis in ischemic stroke. NeuralRegen Res. 2021 Jun;16(6):1017-1023. doi: 10.4103/1673-5374.300452. IF6.1

39.  Cheng Z, Geng X*, Ding Y*. NIHSS Consciousness Score Combined withASPECTS is a Favorable Predictor of Functional Outcome post EndovascularRecanalization in Stroke Patients. Aging Dis. 2021;12(2):415-424. IF10.0

40.  Jiang Q, Stone C, Elkin K, Geng X*, Ding Y*.Immunosuppression and Neuroinflammation in Stroke Pathobiology. ExpNeurobiol. 2021;30(2):101-112. IF 3.8

41.  Lv S, Zhao W, Rajah B, Dandu C, Cai L,Cheng C, Duan H, Dai Q, Geng X*,Ding Y*. Rapid Intervention of Chlorpromazine and Promethazine forHibernation-like Effect in Stroke (RICHES):Rationale, Design and Protocol for aProspective Randomized Controlled Trial. Front Neurol.2021;12:621476. IF 4.1

42.  Geng X, Wang Q, Lee H, Huber C, Wills M, ElkinK, Li F, Ji X*, Ding Y. Remote Ischemic Postconditioning vs. Physical ExerciseAfter Stroke: an Alternative Rehabilitation Strategy?. Mol Neurobiol. 202158(7):3141-3157.. IF5.7

43.  Han Z, Zhao W, Lee H, Tong Y, Cheng Z, DaiQ, Li X, Geng X*, Ding Y.Remote Ischemic Conditioning with Exercise (RICE)- Rehabilitative Strategy inPatients with Acute Ischemic Stroke: Rationale, Design and Protocol for aRandomized Controlled Study. Front Neurol. 2021;12:654669. IF 4.1

44.  Li F, GengX*,Yun H, Haddad Y, Chen Y, Ding Y*. Neuroplastic Effect of ExerciseThrough Astrocytes Activation and Cellular Crosstalk. Aging Dis.2021;12(7):1644-1657. IF 10.0

45.  Cheng Z, Geng X*, Rajah G, Gao J, Ma L, Li F, Du H, Ding Y*. NIHSSConsciousness Score Combined with ASPECTS is a Favorable Predictor ofFunctional Outcome post Endovascular Recanalization in Stroke Patients. AgingDis. 2021;12(2):415-424. IF 10.0

46.  Guo S, Cosky E, Li F, Guan L, Ji Y, Wei W,Peng C, Geng X*, Ding Y*. AnInhibitory and Beneficial Effect of Chlorpromazine and Promethazine (C+P) onHyperglycolysis through HIF-1α Regulation in Ischemic Stroke. Brain Res.2021;1763:147463. IF 3.6

47.  Jiang Q, Mélissa W, Geng X*, Ding Y*.Chlorpromazine and Promethazine ReducesBrain Injury through RIP1-RIP3 Regulated Activation of NLRP3 InflammasomeFollowing Ischemic Stroke. Neurol Res.2021:1-9. IF 2.5

48.   Wang Q,Wills M, Li F, Geng X*, DingY. Remote Ischemic Conditioning with Exercise (RICE) Promotes FunctionalRehabilitation Following Ischemic Stroke. Neurol Res,2021. 20:1-10. IF 2.5

49.  Wang M, Geng X*,  Dandu C, Patel R, Ding Y*. Normobaric Oxygen (NBO)Therapy Improves Cerebral Ischemia/Reperfusion Injury Through Inhibition of EarlyAutophagy. Evid Based Complement Alternat Med. 2021; 30;2021:7041290. IF 2.6

50.   Cai L,Duan H, Saymuah S, Xin R, Geng X*,Ding Y*. Direct, nonVitamin K antagonist oral anticoagulants compared withwarfarin for stroke with atrial fbrillation and cerebral small vessel disease.Environmental Disease. 2021

51.   Cai L,Rajah G, Duan H, Gao J, Cheng Z, Xin R, Jiang S, Palmer P, Geng X*, Ding Y*. Rapid Intravenous Glyceryl Trinitrate inIschemic Damage (RIGID) after Stroke: A Rationale, Design and Protocol for ProspectiveRandomized Controlled Trial. Front Neurol. 2021;12:693330. IF 4.1

52.  Li F, GengX*, Huber C, Stone C, Ding Y*. In Search of a Dose: The Functional andMolecular Effects of Exercise on Post-stroke Rehabilitation in Rats. FrontCell Neurosci. 2020, 14: 186. IF 6.1

53.  Jiang Q, Geng X*, Warren J, Eugene Paul Cosky E, Kaura S, Stone C, LiF, Ding Y. Hypoxia Inducible Factor-1α (HIF-1α) Mediates NLRP3Inflammasome-Dependent-Pyroptotic and Apoptotic Cell Death Following IschemicStroke. Neuroscience. 2020, 448: 126-139. IF 3.7

54.  Zeng Y, Huang X, Elkin K, Stone C, RajahGB, Guan L, Du H, Geng X*.Apolipoprotein E polymorphism carriers exhibit objective cognitive deficits: asingle center trial. Neurol Res. 2020, 42(8): 676-682. IF 2.5

55.  Stone C, Geng X*, Ding Y*. The pursuit of cures for cerebral diseasepersists, even through a pandemic. Neurol Res. 2020, 42(8): 619-620. IF2.5

56.  Wang M, Lee H, Elkin K, Bardhi R, Guan L,Chandra A, Geng X*, Ding Y.Detrimental and Beneficial Effect of Autophagy and a Potential TherapeuticTarget after Ischemic Stroke. Evid Based Complement Alternat Med.2020;2020:8372647. IF 2.6

57.  Du X, Yang J, Liu C, Wang S, Zhang C, ZhaoH, Du H*, Geng X*.Hypoxia-inducible factor 1α and 2α have beneficial effects in remote ischemicpreconditioning against stroke by modulating inflammatory responses in agedrats. Front Aging Neurosci. 2020;12:54. IF 5.7

58.  Chen C*, Zhang C, Liu C, Geng X*. Plasmacytoid dendriticcells protect against middle cerebral artery occlusion induced brain injury bypriming regulatory t cells. Front Cell Neurosci. 2020;14:8. IF 6.1

59.  Liu C*, Yang J, Zhang C, Geng X*, Zhao H. Remote ischemicconditioning reduced cerebral ischemic injury by modulating inflammatoryresponses and erk activity in type 2 diabetic mice. Neurochem Int.2020;135:104690. IF 4.3

60.  Tong Y, Elkin K, Peng C, Shen J, Li F,Guan L, Ji Y, Wei W, Geng X*,Ding Y. Reduced Apoptotic Injury by Phenothiazine in Ischemic Stroke throughthe NOX-Akt/PKC Pathway. Brain Sci. 2019;9:378. 

61.  Cheng Z, Geng X*, Gao J, Hussain M, Moon S, Du H, Ding Y*.Intravenous Administration of Standard Dose Tirofiban after Mechanical ArterialRecanalization is Safe and Relatively Effective in Acute Ischemic Stroke.Aging Dis. 2019;10:1049-1057. IF 10.0

62.  Liu C*, Zhang C, Du H, Geng X*, Zhao H. Remote ischemicpreconditioning protects against ischemic stroke in streptozotocin-induceddiabetic mice via anti-inflammatory response and anti-apoptosis. Brain Res.2019;1724:146429. IF 3.6

63.  Duan H, Huber M, Ding J, Huber C, Geng X*. Local endovascularinfusion and hypothermia in stroke therapy: A systematic review. Brain Circ.2019;5:68-73.

64.  Guan L, Guo S, Yip J, Elkin KB, Li F, PengC, Geng X*, Ding Y*.Artificial hibernation by phenothiazines: A potential neuroprotective therapyagainst cerebral inflammation in stroke. Curr Neurovasc Res.2019;16:232-240. IF 2.3

65.  Zhu H, Chandra A, Geng X*, Cheng Z, Tong Y, Du H, Ding Y. Low dose concomitanttreatment with chlorpromazine and promethazine is safe in acute ischemicstroke. JNeurosurgSci.2019;63:265-269. IF 2.4

66.  Zhu Y, Klomparens EA, Guo S, Geng X*. Neuroinflammationcaused by mental stress: The effect of chronic restraint stress and acuterepeated social defeat stress in mice. Neurol Res. 2019;41:762-769. IF2.5

67.  Han Y, Rajah GB, Hussain M, Geng X*. Clinical potential ofpre-reperfusion hypothermia in ischemic injury. Neurol Res. 2019;41:697-703.IF2.5

68.  Zhu H, Geng X*, Rajah GB, Fu P, Du H. Brain ultrasound fordiagnosis and prognosis in the neurological intensive care unit: A mini reviewfor current development. Neurol Res. 2019;41:691-696. IF 2.5

69.  Tong Y, Cheng Z, Rajah GB, Duan H, Cai L,Zhang N, Du H, Geng X*, DingY*. High intensity physical rehabilitation later than 24 h post stroke isbeneficial in patients: A pilot randomized controlled trial (RCT) study in mildto moderate ischemic stroke. Front Neurol. 2019;10:113. IF 4.1

70.  Shen J, Rastogi R, Geng X*, Ding Y*. Nicotinamide adenine dinucleotidephosphate oxidase activation and neuronal death after ischemic stroke. NeuralRegen Res. 2019;14:948-953. IF 6.1

71.  Jiang Q, Stone C, Geng X*, Ding Y. Hypoxia-inducible factor-1 and rip3triggers nlrp3 inflammasome in ischemic stroke. Brain Circ.2019;4:191-192.

72.  Guan L, Geng X*, Stone C, Cosky EEP, Ji Y, Du H, Zhang K, Sun Q,Ding Y*. PM2.5 exposure induces systemic inflammation and oxidative stress inan intracranial atherosclerosis rat model. Environ Toxicol.2019;34:530-538. IF 4.1

73.  Li F, Yang Z, Stone C, Ding JY, Previch L,Shen J, Ji Y, Geng X*, DingY*. Phenothiazines enhance the hypothermic preservation of liver grafts: Apilot in vitro study. Cell Transplant. 2019;28:318-327. IF 4.1

74.  Li F, GengX*, Yip J, Ding Y*. Therapeutic target and cell-signal communication ofchlorpromazine and promethazine in attenuating blood–brain barrier disruptionafter ischemic stroke. Cell Transplant. 2019;28:145-156. IF 4.1

75.  Liu C*, Yang J, Zhang C, Geng X*, Zhao H. The changes ofsystemic immune responses during the neuroprotection induced by remote ischemicpostconditioning against focal cerebral ischemia in mice. Neurol Res.2019;41:26-36. IF 2.5

76.  Shen J, Rastogi R, Guan L, Li F, Du H*, Geng X*, Ding Y. Omega-3 fattyacid supplement reduces activation of nadph oxidase in intracranialatherosclerosis stenosis. Neurol Res. 2018;40:499-507. IF 2.5

77.  Zeng Y, Yip J, Cui H, Guan L, Zhu H, ZhangW, Du H*, Geng X*. Efficacyof neuromuscular electrical stimulation in improving the negative psychologicalstate in patients with cerebral infarction and dysphagia. Neurol Res.2018;40:473-479. IF 2.5

78.  Ran Y, Liu Z, Huang S, Shen J, Li F, ZhangW, Chen C, Geng X, Ji Z, DuH, Hu X*. Splenectomy Fails to Provide Long-Term Protection Against IschemicStroke. Aging Dis. 2018;9:467-479. IF 10.0

79.  Geng X, Li F,Yip J, Peng C, Elmadhoun O, Shen J, Ji X*, Ding Y*. Neuroprotection bychlorpromazine and promethazine in severe transient and permanent ischemicstroke. Mol Neurobiol. 2017;54:8140-8150.

80.  Zhu Y, Anand R, Geng X*, Ding Y. A mini review: Garlic extract and vasculardiseases. Neurol Res. 2018;40:421-425. IF 2.5

81.  Li F, GengX*, Khan H, Pendy JT, Jr., Peng C, Li X, Rafols JA, Ding Y*.Exacerbation of brain injury by post-stroke exercise is contingent uponexercise initiation timing. Front Cell Neurosci. 2017;11:311. IF 6.1

82.  Tong Y, Pendy JT, Jr., Li WA, Du H, ZhangT, Geng X*, Ding Y*. Motorimagery-based rehabilitation: Potential neural correlates and clinicalapplication for functional recovery of motor deficits after stroke. AgingDis. 2017;8:364-371. IF 10.0

83.  Li F, Pendy JT, Jr., Ding JN, Peng C, LiX, Shen J, Wang S, Geng X*.Exercise rehabilitation immediately following ischemic stroke exacerbatesinflammatory injury. Neurol Res. 2017;39:530-537. IF 2.5

84.  Li F, Shi W, Zhao EY, Geng X*, Li X, Peng C, Shen J, Wang S, Ding Y*. Enhancedapoptosis from early physical exercise rehabilitation following ischemicstroke. J Neurosci Res. 2017;95:1017-1024. IF 4.4

85.  Hussain M, Datta N, Chen Z, Bashir A,Mehta T, Shweikeh F, Mazaris P, Lee N, Nouh A, Geng X*, Ding Y*. Spanning From the West to East: An UpdatedReview on Endovascular Treatment of Intracranial Atherosclerotic Disease. AgingDis. 2017;8:196-202. IF 10.0

86.  Ma L, Guan L, Ding JN, Geng X*. Current AQP Research:Therapeutic Approaches to Ischemic and Hemorrhagic Stroke. Neural Regen Res.2016;11:1918-1919. IF 6.1

87.  RastogiR, Geng X*, Li F, Ding Y*. NOX Activation by SubunitInteraction and Underlying Mechanisms in Disease. Front Cell Neurosci.2017;10:301. IF 6.1

88.  Chandra A, Li W, Stone C, Geng X*, Ding Y. The cerebralcirculation and cerebrovascular disease i: Anatomy. Brain Circ.2017;3:45-56.

89.  Chandra A, Stone C, Li W, Geng X*, Ding Y. The cerebralcirculation and cerebrovascular disease ii: Pathogenesis of cerebrovasculardisease. Brain Circ. 2017;3(2):57-65.

90.  Chandra A, Stone C, Du X, Li W, Huber M,Bremer R, Geng X*, Ding Y.The cerebral circulation and cerebrovascular disease iii: Stroke. Brain Circ.2017;3(2):66-77.

91.  James Yip, Geng X*, Shen J, Ding Y*. Cerebral Gluconeogenesis andDiseases. Front Pharmacol. 2017;7:521 IF 6.0

92.  Shen J, Huber M, Zhao EY, Peng C, Li F, LiX, Geng X*, Ding Y*. Earlyrehabilitation aggravates brain damage after stroke via enhanced activation ofnicotinamide adenine dinucleotide phosphate oxidase (nox). Brain Res.2016;1648:266-276. IF 3.6

93.  Shen J, Hafeez A, Stevenson J, Yang J, YinC, Li F, Wang S, Du H, Ji X, Rafols JA, GengX*, Ding Y*. Omega-3 fatty acid supplement prevents development ofintracranial atherosclerosis. Neuroscience. 2016;334:226-235. IF 3.6

94.  Previch LE, Ma L, Wright JC, Singh S, Geng X*, Ding Y*. Progress inaqp research and new developments in therapeutic approaches to ischemic andhemorrhagic stroke. Int J Mol Sci. 2016;17:1146. IF6.2

95.  Thibodeau A, Geng X*, Previch LE, Ding Y. Pyruvate dehydrogenase complexin cerebral ischemia- reperfusion injury. Brain Circ. 2016;2: 61-66

96.  Shen J, Stevenson J, Geng X*, Yang J, Yin C, Li F, Wang S, Du H*, Ji X, Ding Y. Anew clinically relevant model for intracranial atherosclerosis in rats. NeurolRes. 2016;38:454-460 IF 2.5

97.  Liu K, Khan H, Geng X*, Zhang J, Ding Y. Pharmacological hypothermia: Apotential for future stroke therapy? Neurol Res. 2016;38:478-490. IF 2.5

98.  Forreider B, Pozivilko D, Kawaji Q, Geng X*, Ding Y*.Hibernation-like neuroprotection in stroke by attenuating brain metabolicdysfunction. Prog Neurobiol. 2017;157:174-187. IF 10.9