1. 国家自然科学基金（面上项目）

项目名称：  m6A读码器YTHDF1/2/3联合调控模式在脑小血管病白质损伤小胶质细胞激活和炎症中的作用

项目编号：  82171268

起止时间：  2022.01~2025.12

项目经费：  55万元

2. 国家自然科学基金（面上项目）

项目名称：  IL4I1调控少突胶质祖细胞分化参与毛柳甙修复脑缺血损伤的髓鞘再生机制

项目编号：  81871021

起止时间：  2019.01~2022.12

项目经费：  56万元

3. 国家自然科学基金（面上项目）

项目名称：  miR-124靶向iASPP在脑缺血小胶质细胞极化表型中的作用及机制研究

项目编号：  81471209

起止时间：  2015.01~2018.12

项目经费：  70万元

1.     Wen Dong#, Ting Gong#, Shunying Zhao, Shaohong Wen, QingfangChen, Mingyu Jiang, Weizhen Ye, Qiuru Huang, Chunjuan Wang, Chunmei Yang,Xiangrong Liu*, Yongjun Wang*. A Novel Extract From Ginkgo biloba InhibitsNeuroinflammation and Maintains White Matter Integrity in Experimental Stroke.Neuroscience, 2023;523:7-19.

2.     WenDong#, Xiangrong Liu#, Zixiao Li, Wenqian Liu, Shunying Zhao,ShaohongWen, Qingfang Chen, Ting Gong, Wentao Chen, Weizhen Ye, Yongjun Wang*.Dualantiplatelet therapy improves functional recovery and inhibitsinflammationafter cerebral ischemic/reperfusion injury. Ann Transl Med.2022;10(6):283.

3.    Wen Dong, QingfangChen,Shunying Zhao, Shaohong Wen, Wentao Chen, Weizhen Ye, Ting Gong, MingyuJiang, Xiangrong Liu*. IKKα contributes to ischemia-induced autophagy afteracute cerebralischemic injury. Ann Transl Med. 2022;10(4):160.

4.    Qi Li, Shaohong Wen,WeizhenYe, Shunying Zhao, Xiangrong Liu*. The potential roles of m(6)Amodification in regulating the inflammatoryresponse in microglia. JNeuroinflammation. 2021;18(1):149.

5.    Chengya Dong, ShaohongWen,Shunying Zhao, Shangfeng Zhao, Min Zhang, Wen Dong, Qingfang Chen, WenqianLiu,Ting Gong, Wentao Chen, Si Sun, Xiangrong Liu*. Salidroside InhibitsReactive Astrogliosis and Glial Scar Formation inLate Cerebral Ischemia via theAkt/GSK-3β Pathway. Neurochem Res. 2021;46(4):755-769.

6.    Wen Dong, ShunyingZhao,Shaohong Wen, Chengya Dong, Qingfang Chen, Ting Gong, Wentao Chen, WenqianLiu,Liting Mu, Honglin Shan, Xiaoxuan Xie, Xiangrong Liu*. A preclinicalrandomized controlled study of acute cerebral ischemiatreated with Ginkgobiloba extracts: Are complex components beneficial to acutestroke? CurrentResearch in Translational Medicine. 2020;68(4):197-203.

7.    Xiangrong Liu, ShaohongWen,Shunying Zhao, Feng Yan, Shangfeng Zhao, Di Wu, Xunming Ji*. MildTherapeutic HypothermiaProtects the Brain from Ischemia/Reperfusion Injurythrough Upregulation ofiASPP. Aging and disease. 2018;9(3):401-411.

8.    Xiangrong Liu, ShaohongWen,Feng Yan, Kuan Liu, Liqiang Liu, Lei Wang, Shangfeng Zhao, Xunming Ji.Salidroside provides neuroprotection by modulatingmicroglial polarization aftercerebral ischemia. J Neuroinflammation. 2018;15(1):39.

9.    Xiangrong Liu, Jun Kang, SiSun, Yumin Luo,Xunming Ji, Xianwei Zeng*, Shangfeng Zhao*. MiR-124 targetingiASPP is aberrantlyexpressed in astrocytoma and regulates malignant glioma cellmigration and growth.Mol MedRep. 2018;17（1）: 1970-1978.

10.  Li-QiangLiu#, Xiang-Rong Liu#, Jing-Yan Zhao,Feng Yan,Rong-Liang Wang, Shao-Hong Wen, Lei Wang, Yu-Min Luo, Xun-Ming Ji*.Brain-selective mild hypothermia promoteslong-term white matter integrity afterischemic stroke in mice. CNS Neurosci Ther. 2018;24(12):1275-1285.

11.  Xiangrong Liu, Di Wu, ShaohongWen, Shunying Zhao, Ao Xia, FangLi, Xunming Ji*. Mildtherapeutic hypothermia protects against cerebralischemia/reperfusion by inhibitingmiR-15b expression in rats. Brain Circ.2017;3(4):219-226.

12.  Xiangrong Liu, Jun Kang, FangLiu, Shaohong Wen, Xianwei Zeng,Kuan Liu, Yumin Luo, Xunming Ji, Shangfeng Zhao*. Overexpression ofiASPP-SV inglioma is associated with poor prognosis by promoting cellviability andantagonizing apoptosis. Tumor Bio. 2016;37(5):6323-6330.

13.  XiangrongLiu, Jia Liu, Shangfeng Zhao, Haiyue Zhang, Wei Cai,XunmingJi, Rehana Leak, Yanqin Gao, Jun Chen, Xiaoming Hu*. Interleukin-4isEssential for Microglia/Macrophage M2 Polarization and Long-term RecoveryafterCerebral Ischemia. Stroke. 2016;47(2):498-504.

14.  Xiangrong Liu, ShangfengZhao, Fang Liu, JunKang, Ao Xiao, FangLi, Chencheng Zhang, Feng Yan, HaipingZhao, Mei Luo, Yumin Luo, Xunmin Ji*.Remoteischemic postconditioning alleviates cerebral ischemic injury byattenuatingendoplasmic reticulum stress-mediated apoptosis. Transl StrokeRes.2014;5(6):692-700.

15.  XiangrongLiu, Fang Li, Shangfeng Zhao, Yumin Luo, Jun Kang,HaipingZhao, Feng Yan, Sijie Li, Xunming Ji*. MiRNA-124-mediated regulation ofinhibitory member ofapoptosis stimulating protein of p53 family in experimentalstroke. Stroke.2013;44(7):1973-1980.

16.  Xiang-Rong Liu, Mei Luo, Feng Yan, Chen-Cheng Zhang,Si-Jie Li,Hai-Ping Zhao, Xun-Ming Ji*, Yu-Min Luo*. Ischemic postconditioningdiminishesmatrix metalloproteinase 9 expression and attenuates loss of theextracellular matrix proteinsin rats following middle cerebral artery occlusionand reperfusion. CNS Neuroscience & Therapeutics. 2012;18(10):855-863.

17.  XiangrongLiu#, Lei Wang#, Shangfeng Zhao, Xunming Ji, YuminLuo,Feng Ling*. β-cateninoverexpression in malignant glioma and its role inproliferation and apoptosisin glioblastma cells. Med Oncol. 2011;28(2):608-614.

18.  Xiangrong Liu#, Qing Zhang#, Dong-er Zhang, Chunlin Zhou,HaiyanXing, Zheng Tian, Qing Rao, Min Wang, Jianxiang Wang*. Overexpression ofan isoform of AML1 in acute leukemia and its potential role inleukemogenesis.Leukemia. 2009; 23(4):739-745.