2025年6月，姚顺颖、吴佳欣毕业，课题组合影。

2024年6月， 李辉、杨晓笛毕业，课题组合影

2023年教师节师生合影

2021年 教师节师生合影

1)  有机磷阻燃剂及其降解产物的膳食暴露评估、健康指导值制定与暴露风险特征分析，北京市教委-北京市自然科学基金联合资助重点项目，北京市教育委员会科技计划重点项目, 2023.1-2025.12

2）食品中有机磷酸酯及其降解产物的检测技术研发及北京居民膳食暴露评估，首都卫生发展科研专项, 2022.01-2024.12

3)  基于北京市总膳食研究的四溴双酚A/S类阻燃剂的人群暴露评估与甲状腺干扰效应研究，北京市教委-北京市自然科学基金联合资助项目，北京市教育委员会科技计划重点项目, 2019.1-2021.12

4) 十溴二苯乙烷的人群暴露评估及长期暴露的肝脏毒性效应研究, 国家自然科学基金面上项目，21777107，2018.1-2021.12

5) 溴系阻燃剂的母婴暴露评估及母体孕期/哺乳期暴露对子代神经发育的影响，国家自然科学基金面上项目，2015.1-2018.12

6) 典型溴系阻燃剂的暴露评估及低剂量暴露的代谢组学研究，国家自然科学基金青年基金， 2011.01-2013.12

7) 北京市食品中溴系阻燃剂的污染状况及其健康效应探索，北京市自然科学基金面上项目，2012.01-2014.12

1)  有机磷阻燃剂及其降解产物的膳食暴露评估、健康指导值制定与暴露风险特征分析，北京市教委-北京市自然科学基金联合资助重点项目，北京市教育委员会科技计划重点项目, 2023.1-2025.12

2）食品中有机磷酸酯及其降解产物的检测技术研发及北京居民膳食暴露评估，首都卫生发展科研专项, 2022.01-2024.12

3)  基于北京市总膳食研究的四溴双酚A/S类阻燃剂的人群暴露评估与甲状腺干扰效应研究，北京市教委-北京市自然科学基金联合资助项目，北京市教育委员会科技计划重点项目, 2019.1-2021.12

4) 十溴二苯乙烷的人群暴露评估及长期暴露的肝脏毒性效应研究, 国家自然科学基金面上项目，21777107，2018.1-2021.12

5) 溴系阻燃剂的母婴暴露评估及母体孕期/哺乳期暴露对子代神经发育的影响，国家自然科学基金面上项目，2015.1-2018.12

6) 典型溴系阻燃剂的暴露评估及低剂量暴露的代谢组学研究，国家自然科学基金青年基金， 2011.01-2013.12

7) 北京市食品中溴系阻燃剂的污染状况及其健康效应探索，北京市自然科学基金面上项目，2012.01-2014.12

2025年

1. Mohammad Hadi Dehghani*, Mina Aghaei*, Parnia Bashardoust, Mohammad Rezvani Ghalhari, Danial Nayeri, Milad Malekpoor, Samira Sheikhi and Zhixiong Shi*, An insight into the environmental and human health impacts of perand polyfluoroalkyl substances (PFAS): exploring exposure pathways and their implications, Environmental Sciences Europe (2025) 37:81, 10.1186/s12302-025-01122-9

2. Shunying Yao, Lei Zhang*, Bing Lyu, Yaoyu Tang, Jingguang Li, Zhixiong Shi*, Organophosphate esters and their metabolites in paired maternal serum and human milk: Occurrence, transfer efficiency, and metabolic conversion, Journal of Environmental Sciences, 2025, 10.1016/j.jes.2025.05.064

3. Xuezhen Zhao#, Lei Zhang#, Bing Lyu, Jingguang Li, Yunfeng Zhao, Yongning Wu, Zhixiong Shi*, Integrated risk assessment of dietary exposure and body burden of three brominated flame retardants in childbearing-aged Chinese women and breastfeeding infants, Environmental Research, 2025, 269, 120881 https://doi.org/10.1016/j.envres.2025.120881

2024年

4. Xia Cui#, Shunying Yao#, Haixian Jia, Xiaochen Ma, Sai Fan*, Zhixiong Shi*, Organophosphate esters and their metabolites in Beijing Total Diets: occurrence, time trend, and dietary exposure assessment, Food and Chemical Toxicology, 2024, 194, 115103. https://doi.org/10.1016/j.fct.2024.115103

5. Jiaxin Wu#, Shunying Yao#, Yiwei Wang, Sai Fan, Xia Cui, Dawei Chen*, Zhixiong Shi*，Fast determination of organophosphate esters and their metabolites in human matrices by a straightforward cold-induced strategy coupled with HPLC-MS/MS, Analytical and Bioanalytical Chemistry, 2024, 416:6663-6677.   doi.org/10.1007/s00216-024-05572-7 

6. Shunying Yao, Xuelei Chen, Bing Lyu, Lei Zhang, Yongning Wu, Jiaying Liu*, Zhixiong Shi*, Comprehensive dietary exposure assessment of the Chinese population to organophosphate esters (OPEs): Results of the sixth China total diet study, Chemosphere, 2024, 364, 143281.

7. Yu Tang#, Pingping Zhou#, Xiaodan Wang, Pei Cao, Xiujuan Li, Jinyao Chen, Lishi Zhang, Nan Wu, Qi Li, Shunying Yao, Lei Zhang*, Zhixiong Shi*, Organophosphate Esters in Raw Cow Milk and Cow’s Drinking Water and Feed from China: Occurrence, Regional Distribution, and Dietary Exposure Assessment, Journal of Agricultural and Food Chemistry, 2024, 72, 18434-18444. https://doi.org/10.1021/acs.jafc.4c05098 

8. Hui Li, Bing Lyu, Jingguang Li, Zhixiong Shi*, Liquid crystal monomers (LCMs) in indoor residential dust from Beijing, China: occurrence and human exposure, Environmental Science and Pollution Research, 2024, 31:29859-29869

9. Jinglong Xue, Xiangyang Li, Yafei Chi, Leqiang Gao, Yue Zhang, Yan Wang, Moxuan Zhao, Jialiu Wei, Zhixiong Shi∗, Xianqing Zhou∗, Decabromodiphenyl ether induces the chromosome association disorders of spermatocytes and deformation failures of spermatids in mice, Journal of Environmental Sciences, 2024, 138, 531–542 (IF= 6.796) 

2023年

10. Li Jing, Zhixiong Shi*, Per- and polyfluoroalkyl substances (PFAS) exposure might be a risk factor for thyroid cancer, eBioMedicine, 2023, 98, 104866

11. Jiaying Liu, Linlin Song, Jing Zhan, Yunxin Zhong, Zhixiong Shi*, Occurrence of legacy and alternative per- and polyfluoroalkyl substances in serum from high exposure population and their disrupting effects on serum lipids and thyroid function, Science of the Total Environment, 2023, 878, 162988 

12. Xiangyang Li#, Yue Zhang#, Leqiang Gao, Xiaodi Yang, Guiqing Zhou, Yujian Sang, Jinglong Xue, Zhixiong Shi*, Zhiwei Sun, Xianqing Zhou*, BDE-209 induced spermatogenesis disorder by inhibiting SETD8/H4K20me1 related histone methylation in mice, Science of the Total Environment, 2023, 864, 161162 

13. Li Jing, Dan Zheng, Xuejing Sun, Zhixiong Shi*, DBDPE upregulates NOD-like receptor signaling to induce NLRP3 inflammasome-mediated HAECs pyroptosis, Environmental Pollution, 2023, 318, 120882

14. Shunying Yao#, Zhixiong Shi#, Pei Cao, Lei Zhang, Yu Tang, Pingping Zhou*, Zhaoping Liu*, A global survey of organophosphate esters and their metabolites in milk: Occurrence and dietary intake via milk consumption. Journal of Hazardous Materials, 2023, 442, 130080.

15. Xuezhen Zhao, Bing Lyu*, Lei Zhang, Jingguang Li, Yunfeng Zhao, Yongning Wu, Zhixiong Shi*, Legacy and novel brominated flame retardants in animal-derived foods from China Total Diet Study (CTDS): Temporal trends, evidence of substitution, and dietary exposure assessment. Journal of Hazardous Materials, 2023, 443, 130223.

2022年

16. Xuelei Chen, Nan Zhang, Liping Li, Rong Zhao, Ning Chen, Sai Fan*, Zhixiong Shi*, A simple method for simultaneous determination of organophosphate esters and their diester metabolites in dairy products and human milk by using solid phase extraction coupled to liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry, 2022, 414, 4255-4265

17. Ning Chen#, Sai Fan#, Nan Zhang, Yao Zhao, Shunying Yao, Xuelei Chen, Xiaofeng Liu*, Zhixiong Shi*, Organophosphate esters and their diester metabolites in infant formulas and baby supplementary foods collected in Beijing, China: Occurrence and the implications for infant exposure. Science of the Total Environment, 2022, 827: 154272

18. Tian Chen#, Xueting Wang#, Jiaxin Jia, Dejun Wang, Yanxin Gao, Xin Yang, Shixuan Zhang, Piye Niu*, Zhixiong Shi*, Reduced mitochondrial DNA copy number in occupational workers from brominated flame retardants manufacturing plants, Science of the Total Environment, 2022, 809, 151086 

19. Li Jing#, Yanmin Sun#, Ji Wang, Xianqing Zhou, Zhixiong Shi*, Oxidative stress and endoplasmic reticulum stress contributed to hepatotoxicity of decabromodiphenyl ethane (DBDPE) in L-02 cells, Chemosphere, 2022, 286:131550

2021年

20. Xuelei Chen#, Sai Fan#, Bing Lyu, Lei Zhang, Shunying Yao, Jiaying Liu,* Zhixiong Shi,* Yongning Wu, Occurrence and Dietary Intake of Organophosphate Esters via Animal-Origin Food Consumption in China: Results of a Chinese Total Diet Study, Journal of Agricultural and Food Chemistry, 2021, 69, 13964−13973

21. Xuezhen Zhao, Zhixiong Shi*, Legacy brominated flame retardants in human milk from the general population in Beijing, China: Biomonitoring, temporal trends from 2011 to 2018, and nursing infant’s exposure assessment, Chemosphere, 2021, 285:131533

22. Xuelei Chen, Wei Li, Jingguang Li, Sai Fan, Zhixiong Shi*, Rapid determination of 13 organophosphorus flame retardants in milk by using modified quick, easy, cheap, effective, rugged, and safe technique, solid-phase extraction, and HPLC-MS/MS, Journal of Separation Science, 2021, 44(11): 2269-2278

23. Xuelei Chen, Xuezhen Zhao, Zhixiong Shi*, Organophosphorus flame retardants in breast milk from Beijing, China：Occurrence, nursing infant’s exposure and risk assessment, Science of the Total Environment, 2021, 771, 145404

24. Xuezhen Zhao#, Xiaodi Yang#, Yinglin Du, Renbo Li, Tao Zhou, Yuwei Wang, Tian Chen, Dejun Wang*, Zhixiong Shi*, Polybrominated diphenyl ethers in serum from residents living in a brominated flame retardant production area: Occurrence, influencing factors, and relationships with thyroid and liver function, Environmental Pollution, 2021, 270, 116046

25. Xuezhen Zhao#, Tian Chen#, Bin Yang, Dejun Wang, Wen Sun, Yuwei Wang, Xiaodi Yang, Sheng Wen, Jingguang Li*, Zhixiong Shi*, Serum levels of novel brominated flame retardants (NBFRs) in residents of a major BFR-producing region: Occurrence, impact factors and the relationship to thyroid and liver function, Ecotoxicology and Environmental Safety, 2021, 208, 111467

2020年

26. Xuezhen Zhao#, Tian Chen#, Dejun Wang, Yinglin Du, Yan Wang, Wenwen Zhu, Melikedilnur Bekir, Dong Yu*, Zhixiong Shi*, Polybrominated diphenyl ethers and decabromodiphenyl ethane in paired hair/serum and nail/serum from corresponding chemical manufacturing workers and their correlations to thyroid hormones, liver and kidney injury markers, Science of the Total Environment, 2020, 729, 139049

27. Jiandi Wang, Jian Li, Zhixiong Shi*, Dietary exposure assessment of a nursing mother-infant cohort to legacy and novel brominated flame retardants: Results of a 3-day duplicate diet study in Beijing, China, Chemosphere, 2020, 254:126843

28. Morong Huang#, Jian Li#, Zhongxin Xiao, Zhixiong Shi*, Tetrabromobisphenol A and hexabromocyclododecane isomers in breast milk from the general population in Beijing, China: Contamination levels, temporal trends, nursing infant’s daily intake and risk assessment, Chemosphere, 2020, 244: 125524

29. Yanmin Sun, Yuwei Wang, Baolu Liang, Tian Chen, Dan Zheng, Xuezhen Zhao, Li Jing*, Xianqing Zhou, Zhiwei Sun, Zhixiong Shi*, Hepatotoxicity of decabromodiphenyl ethane (DBDPE) and decabromodiphenyl ether (BDE-209) in 28-day exposed Sprague-Dawley Rats, Science of the Total Environment, 2020, 705, 135783

2019年

30. Tian Chen, Morong Huang, Jian Li, Jingguang Li, Zhixiong Shi*, Polybrominated diphenyl ethers and novel brominated flame retardants in human milk from the general population in Beijing, China: Occurrence, temporal trends, nursing infants’ exposure and risk assessment, Science of the Total Environment, 2019, 689:278-286 

31. Tian Chen, Dong Yu, Luping Yang, Shaofeng Sui, Shibo Lv, Yi Bai, Wen Sun, Yuwei Wang, Li Chen, Zhiwei Sun, Lin Tian, Dejun Wang*, Piye Niu*, Zhixiong Shi*, Thyroid function and decabromodiphenyl ethane (DBDPE) exposure in Chinese adults from a DBDPE manufacturing area, Environment International, 2019, 133:105179 

32. Dejun Wang#, Tian Chen#, Zhongjian Fu, Luping Yang, Renbo Li, Shaofeng Sui, Yuwei Wang, Zhixiong Shi*, Occupational exposure to polybrominated diphenyl ethers or decabromodiphenyl ethane during chemical manufacturing: Occurrence and health risk assessment, Chemosphere, 2019, 231:385-392

33. Yuwei Wang#, Tian Chen#, Yanmin Sun, Xuezhen Zhao, Dan Zheng, Li Jing*, Xianqing Zhou, Zhiwei Sun, Zhixiong Shi*, A comparison of the thyroid disruption induced by decabrominated diphenyl ethers (BDE-209) and decabromodiphenyl ethane (DBDPE) in Rats, Ecotoxicology and Environmental Safety, 2019, 174:224-235

34. Jiandi Wang, Xuezhen Zhao, Yifei Wang, Zhixiong Shi*, Tetrabromobisphenol A, hexabromocyclododecane isomers and polybrominated diphenyl ethers in foodstuffs from Beijing, China: Contamination levels, dietary exposure and risk assessment, Science of the Total Environment, 2019, 666:812-820 

35. Li Jing, Yanmin Sun, Yuwei Wang, Baolu Liang, Tian Chen, Dan Zheng, Xuezhen Zhao, Xianqing Zhou, Zhiwei Sun, Zhixiong Shi*, Cardiovascular toxicity of decabrominated diphenyl ethers (BDE-209) and decabromodiphenyl ethane (DBDPE) in rats, Chemosphere, 2019, 223:675-685 

2018年

36. Yuwei Wang, Yanmin Sun, Tian Chen, Zhixiong Shi*, Xianqing Zhou, Zhiwei Sun, Lei Zhang, Jingguang Li*, Determination of polybrominated diphenyl ethers and novel brominated flame retardants in human serum by gas chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry, Journal of Chromatography B, 2018, 1099: 64-72

37. Tian Chen#, Piye Niu#, Fanling Kong, Yuwei Wang, Yi Bai, Dong Yu, Jiaxin Jia, Luping Yang, Zhongjian Fu, Renbo Li, Jingguang Li, Lin Tian, Zhiwei Sun, Dejun Wang*, Zhixiong Shi*, Disruption of thyroid hormone levels by decabrominated diphenyl ethers (BDE-209) in occupational workers from a deca-BDE manufacturing plant, Environment International, 2018, 120:505-515

38. Zhixiong Shi, Lei Zhang, Jingguang Li, Yongning Wu*, Legacy and emerging brominated flame retardants in China: A review on food and human milk contamination, human dietary exposure and risk assessment, Chemosphere, 2018, 198:522-536 

39. Jiandi Wang#, Yuwei Wang#, Zhixiong Shi*, Xianqing Zhou, Zhiwei Sun. Legacy and novel brominated flame retardants in indoor dust from Beijing, China: Occurrence, human exposure assessment and evidence for PBDEs replacement, Science of the Total Environment, 2018, 618:48-59

2017年

40. Zhixiong Shi*, Lei Zhang, Yunfeng Zhao, Zhiwei Sun, Xianqing Zhou, Jingguang Li*, Yongning Wu. Dietary exposure assessment of Chinese population to tetrabromobisphenol-A, hexabromocyclododecane and decabrominated diphenyl ether: Results of the 5th Chinese Total Diet Study, Environmental Pollution, 2017, 229:539-547 

41. Zhixiong Shi*, Lei Zhang, Yunfeng Zhao, Zhiwei Sun, Xianqing Zhou, Jingguang Li*, Yongning Wu. A National Survey of Tetrabromobisphenol-A, Hexabromocyclododecane and Decabrominated Diphenyl Ether in Human Milk from China: Occurrence and Exposure assessment, Science of the Total Environment, 2017, 599-600:237-245

42. Jian Li#, Tian Chen#, Yuwei Wang, Zhixiong Shi*, Xianqing Zhou, Zhiwei Sun, Dejun Wang*, Yongning Wu, Simple and fast analysis of tetrabromobisphenol A, hexabromocyclododecane isomers, and polybrominated diphenyl ethers in serum using solid-phase extraction or QuEChERS extraction followed by tandem mass spectrometry coupled to HPLC and GC, Journal of Separation Science, 2017, 40(3):709-716

2016年

43. Zhixiong Shi*, Lei Zhang, Jingguang Li, Yunfeng Zhao, Zhiwei Sun, Xianqing Zhou, Yongning Wu*, Novel brominated flame retardants in food composites and human milk from the Chinese Total Diet Study in 2011: Concentrations and a dietary exposure assessment, Environment International, 2016, 96: 82-90

44. Le Gao#, Jian Li#, Yandan Wu, Miaohao Yu, Tian Chen, Zhixiong Shi*, XianQing Zhou, Zhiwei Sun, Determination of novel brominated flame retardants and polybrominated diphenyl ethers in serum using gas chromatography-mass spectrometry with two simplified sample preparation procedures, Analytical and Bioanalytical Chemistry, 2016, 408(27):7835–7844

45. Zhixiong Shi, Yifei Wang, Piye Niu*, Jiandi Wang, Zhiwei Sun, Shuhua Zhang, Yongning Wu, Concurrent extraction, clean-up, and analysis of polybrominated diphenyl ethers, hexabromocyclododecane isomers, and tetrabromobisphenol A in human milk and serum, Journal of Separation Science, 2013, 36(20):3402-3410.

46. Zhixiong Shi*, Yang Jiao, Yue Hu, Zhiwei Sun, Xianqing Zhou, Jinfang Feng, Jingguang Li, Yongning Wu*, Levels of tetrabromobisphenol A, hexabromocyclododecanes and polybrominated iphenyl ethers in human milk from the general population in Beijing, China, Science of the Total Environment, 2013, 452-453:10-18

47. Zhixiong Shi, Yongning Wu*, Jingguang Li, Yunfeng Zhao, Jinfang Feng*. Dietary exposure assessment of Chinese adults and nursing infants to tetrabromobisphenol-A and hexabromocyclododecanes: occurrence measurements in foods and human milk. Environmental Science & Technology, 2009, 43(12):4314-4319