目前任硕士、博士研究生导师，博士后合作导师，已经培养硕士、博士研究生和海外留学生15名研究生，已经毕业8名，2018年和2020年度被评为首都医科大学附属北京安贞医院优秀研究生导师。课题组团队长期致力于心血管疾病的基础和临床研究，研究成果发表在欧洲心脏病学杂志、BMC Medicine，Cardiovasc Drugs Ther，Cardiovasc Diabetol等知名国际期刊，累积影响因子约200余分，两名同学获国家奖学金。

1.项目名称：国家科技重大专项负责人：多维度智能化重大慢病相关临床质谱适宜技术体系的建立-基于多维度质谱技术的冠心病及共病新型风险标志物的发现和精准检验研究。项目起止时间：2025.02-2029.01；项目总经费（270万元）

2.项目名称：微塑料在动脉中的积累规律及其驱动动脉粥样硬化的作用机制

项目来源：北京市科技新星计划

项目起止时间：2024-2026

项目总经费（万元）：30万元

3.国家自然科学基金（面上项目）：促甲状腺素诱导巨噬细胞受训免疫并驱动动脉粥样硬化的作用机制（结题）

4.国家自然科学基金（面上项目）：骨形态发生蛋白2（BMP2）调控细胞外基质重构对斑块进展和稳定性的影响及机制研究（结题）

5.北京市自然科学基金（面上项目）：甲状腺激素调控巨噬细胞凋亡对动脉粥样硬化斑块进展及稳定性的影响（结题）

6.北京市科委项目：甲状腺功能减退症相关冠心病的组学谱及机制研究（结题）

国家科技重大专项负责人：多维度智能化重大慢病相关临床质谱适宜技术体系的建立-基于多维度质谱体系的冠心病及共病新型风险标志物的发现和精准检验研究。（270万）

北京市科技新星项目：微塑料在动脉中的积累规律及驱动动脉粥样硬化的机制（30万）

国家自然科学基金（面上项目）：促甲状腺素诱导巨噬细胞受训免疫并驱动动脉粥样硬化的作用机制

国家自然科学基金（面上项目）：骨形态发生蛋白2（BMP2）调控细胞外基质重构对斑块进展和稳定性的影响及机制研究

北京市自然科学基金（面上项目）：甲状腺激素调控巨噬细胞凋亡对动脉粥样硬化斑块进展及稳定性的影响

北京市科委项目：甲状腺功能减退症相关冠心病的组学谱及机制研究

1.Microplasticsin three types of human arteries detected by pyrolysis-gas chromatography/massspectrometry (Py-GC/MS)》发表在《Journal of HazardousMaterials》（ISSN 0304-3894）2024年5月469卷；

 2.Percutaneouscoronary intervention leads to microplastics entering the blood: Interventionaldevices are a major source》，发表在《Journal of HazardousMaterials》（ISSN 0304-3894）2024年476卷发表

3. Duo Yang,Siyao Ni, Sheng Liu, Chenyang wang, Kexin Yang, Ludan Bi, Zhijian Yue, LiweiHang, Ming Zhang, Hai Gao. (2025). B Lymphocytes and HyperglycemiaSynergistically Exacerbate Coronary In-Stent Restenosis. InternationalJournal of Cardiology Cardiovascular Risk and Prevention, 200475.

4. 倪思瑶,刘圣,王晨阳,杨可馨,毕露丹,岳志坚 & 张铭.(2025).从环境暴露到心血管损伤：微塑料的病理机制与研究进展.中国动脉硬化杂志,33(09),823-828.https://doi.org/10.20039/j.cnki.1007-3949.2025.09.012.

5. Liu S, Wang C, Guo J, Yang Y, Huang M, Li L, Wang Y, Qin Y, Zhang M. Serum Cytokines Predict the Severity of Coronary Artery Disease Without Acute Myocardial Infarction. Front Cardiovasc Med. 2022 May 16;9:896810.SCI

6. Huang M, Liu S, Liu S, Wen W, Ning Y, Jia Y, Yang Y, Jiao X, Zheng W, Zhang M. Circulating ADAMTS13 Levels Are Associated with an Increased Occurrence of Obstructive Sleep Apnea. Dis Markers. 2022 Mar 29;2022:1504137.SCI

7. Jia Y, Wen W, Yang Y, Huang M, Ning Y, Jiao X, Liu S, Qin Y, Zhang M. The clinical role of combined serum C1q and hsCRP in predicting coronary artery disease. Clin Biochem. 2021 Jul;93:50-58. SCI

8. Wanwan Wen , Haili Sun , Yunxiao Yang , Yifan Jia, Fang Fang , Yanwen Qin , Ming Zhang, Yongxiang Wei .Usefulness of Cathepsin S to Predict Risk for Obstructive Sleep Apnea among Patients with Type 2 Diabetes. Dis Markers . 2020,2020:8819134:2020:8819134.SCI

9. Yunxiao Yang , Yu Ning , Wanwan Wen , Yifan Jia , Xiaoyuan Chen , Mengling Huang 1 , Jaskanwal Deep Sara 3 , Yanwen Qin 4 , Fang Fang 4 , Huina Zhang 4 , Yunhui Du 4 , Linyi Li 4 , Xiaolu Jiao , Yunyun Yang , Xingyu Han , Ming Zhang , Yongxiang Wei .CPAP is associated with decreased risk of AF recurrence in patients with OSA, especially those younger and slimmer: a meta-analysis. J Interv Card Electrophysiol. 2020,58(3):369-379.SCI

10. Yunxiao Yang , Yifan Jia , Yu Ning , Wanwan Wen , Yanwen Qin , Huina Zhang , Yunhui Du , Linyi Li , Xiaolu Jiao , Yunyun Yang , Guanghui Liu , Mengling Huang ,Ming Zhang* .TAK1-AMPK Pathw ay in Macrophages Regulates Hypothyroid Atherosclerosis. Cardiovasc Drugs Ther. 2020,doi: 10.1007/s10557-020-06996-w:doi: 10.1007/s10557-020-06996-w.SCI

11. Wan-Wan Wen , Hai-Li Sun , Yun-Xiao Yang , Yi-Fan Jia , Meng-Ling Huang 1 , Yun-Hui Du, Yan-Wen Qin , Fang Fang , Ming Zhang* , Yong-Xiang Wei* .The association between circulating APRIL levels and severity of obstructive sleep apnea in Chinese adults. Clin Chim Acta . 2020,508:161-169.SCI

12. Ning Y, Zhang TS, Wen WW, Li K, Yang YX, Qin YW, Zhang HN, Du YH, Li LY, Yang S, Yang YY, Zhu MM, Jiao XL, Zhang Y, Zhang M*, Wei YX*..Effects of continuous positive airway pressure on cardiovascular biomarkers in patients with obstructive sleep apnea: a meta-analysis of randomized controlled trials.. Sleep Breath. 2019,23(1):77-86.SCI

13. Yang M#, Fan Z#, Wang F, Tian ZH, Ma B, Dong B, Li Z, Zhang M*， Zhao W*..BMP-2 enhances the migration and proliferation of hypoxia-induced VSMCs via actin cytoskeleton, CD44 and matrix metalloproteinase linkage. experimental cell research. 2018,368(2):248-257.SCI

14. Ning Y, Cheng YJ, Liu LJ, Sara JD, Cao ZY, Zheng WP, Zhang TS, Han HJ, Yang ZY, Zhang Y, Wang FL, Pan RY, Huang JL, Wu LL, Zhang M, Wei YX..What is the association of hypothyroidism with risks of cardiovascular events and mortality? A meta-analysis of 55 cohort studies involving 1,898,314 participants.. BMC Med. 2017,15（1）:1-15.SCI

15. Zhang M, Guddeti RR, Matsuzawa Y, Sara JD, Kwon TG, Liu Z, Sun T, Lee SJ, Lennon RJ, Bell MR, Schaff HV, Daly RC, Lerman LO, Lerman A*, Locker C*..Left Internal Mammary Artery Versus Coronary Stents: Impact on Downstream Coronary Stenoses and Conduit Patency.. J Am Heart Assoc. 2016,5（9）:120-130.SCI

16. Zhang M, Sara JD, Matsuzawa Y, Gharib H, Bell MR, Gulati R, Lerman LO, Lerman A..Clinical outcomes of patients with hypothyroidism undergoing percutaneous coronary intervention.. Eur Heart J. 2016,37(26):2055-2066.SCI

17.  Zhang M#, Sara JD, Wang FL, Liu LP, Su LX, Zhe J, Wu X, Liu JH*. .Zhang M#, Sara JD, Wang FL, Liu LP, Su LX, Zhe J, Wu X, Liu JH*. Increased plasma BMP-2 levels are associated with atherosclerosis burden and coronary calcification in type 2 diabetic patients. . Cardiovascular diabetology. 2015,14:64:14:64.SCI