团队具有丰富的冠心病临床诊疗和科研经验。患者对本团队诊疗的满意度高，给予广泛的积极评价，使本医疗团队连续4年入选“年度好大夫”榜单。同时本团队对冠心病的诊断、治疗与预后展开了全面的临床研究，也对动脉粥样硬化的形成机制有较为深入的基础研究，先后承担多项国家和省部级科研项目，有丰富的科研经验，科研成果产出稳定，每年在SCI期刊和中文核心期刊上发表多篇论文。

国家自然科学基金（面上项目）：促甲状腺素诱导巨噬细胞受训免疫并驱动动脉粥样硬化的作用机制

国家自然科学基金（面上项目）：骨形态发生蛋白2（BMP2）调控细胞外基质重构对斑块进展和稳定性的影响及机制研究

北京市自然科学基金（面上项目）：甲状腺激素调控巨噬细胞凋亡对动脉粥样硬化斑块进展及稳定性的影响

北京市科委项目：甲状腺功能减退症相关冠心病的组学谱及机制研究

国家自然科学基金（面上项目）：促甲状腺素诱导巨噬细胞受训免疫并驱动动脉粥样硬化的作用机制

国家自然科学基金（面上项目）：骨形态发生蛋白2（BMP2）调控细胞外基质重构对斑块进展和稳定性的影响及机制研究

北京市自然科学基金（面上项目）：甲状腺激素调控巨噬细胞凋亡对动脉粥样硬化斑块进展及稳定性的影响

北京市科委项目：甲状腺功能减退症相关冠心病的组学谱及机制研究

1. Liu S, Wang C, Guo J, Yang Y, Huang M, Li L, Wang Y, Qin Y, Zhang M. Serum Cytokines Predict the Severity of Coronary Artery Disease Without Acute Myocardial Infarction. Front Cardiovasc Med. 2022 May 16;9:896810.SCI

2. Huang M, Liu S, Liu S, Wen W, Ning Y, Jia Y, Yang Y, Jiao X, Zheng W, Zhang M. Circulating ADAMTS13 Levels Are Associated with an Increased Occurrence of Obstructive Sleep Apnea. Dis Markers. 2022 Mar 29;2022:1504137.SCI

3. Jia Y, Wen W, Yang Y, Huang M, Ning Y, Jiao X, Liu S, Qin Y, Zhang M. The clinical role of combined serum C1q and hsCRP in predicting coronary artery disease. Clin Biochem. 2021 Jul;93:50-58. SCI

4. Wanwan Wen , Haili Sun , Yunxiao Yang , Yifan Jia, Fang Fang , Yanwen Qin , Ming Zhang, Yongxiang Wei .Usefulness of Cathepsin S to Predict Risk for Obstructive Sleep Apnea among Patients with Type 2 Diabetes. Dis Markers . 2020,2020:8819134:2020:8819134.SCI

5. Yunxiao Yang , Yu Ning , Wanwan Wen , Yifan Jia , Xiaoyuan Chen , Mengling Huang 1 , Jaskanwal Deep Sara 3 , Yanwen Qin 4 , Fang Fang 4 , Huina Zhang 4 , Yunhui Du 4 , Linyi Li 4 , Xiaolu Jiao , Yunyun Yang , Xingyu Han , Ming Zhang , Yongxiang Wei .CPAP is associated with decreased risk of AF recurrence in patients with OSA, especially those younger and slimmer: a meta-analysis. J Interv Card Electrophysiol. 2020,58(3):369-379.SCI

6. Yunxiao Yang , Yifan Jia , Yu Ning , Wanwan Wen , Yanwen Qin , Huina Zhang , Yunhui Du , Linyi Li , Xiaolu Jiao , Yunyun Yang , Guanghui Liu , Mengling Huang ,Ming Zhang* .TAK1-AMPK Pathw ay in Macrophages Regulates Hypothyroid Atherosclerosis. Cardiovasc Drugs Ther. 2020,doi: 10.1007/s10557-020-06996-w:doi: 10.1007/s10557-020-06996-w.SCI

7. Wan-Wan Wen , Hai-Li Sun , Yun-Xiao Yang , Yi-Fan Jia , Meng-Ling Huang 1 , Yun-Hui Du, Yan-Wen Qin , Fang Fang , Ming Zhang* , Yong-Xiang Wei* .The association between circulating APRIL levels and severity of obstructive sleep apnea in Chinese adults. Clin Chim Acta . 2020,508:161-169.SCI

8. Ning Y, Zhang TS, Wen WW, Li K, Yang YX, Qin YW, Zhang HN, Du YH, Li LY, Yang S, Yang YY, Zhu MM, Jiao XL, Zhang Y, Zhang M*, Wei YX*..Effects of continuous positive airway pressure on cardiovascular biomarkers in patients with obstructive sleep apnea: a meta-analysis of randomized controlled trials.. Sleep Breath. 2019,23(1):77-86.SCI

9. Yang M#, Fan Z#, Wang F, Tian ZH, Ma B, Dong B, Li Z, Zhang M*， Zhao W*..BMP-2 enhances the migration and proliferation of hypoxia-induced VSMCs via actin cytoskeleton, CD44 and matrix metalloproteinase linkage. experimental cell research. 2018,368(2):248-257.SCI

10. Ning Y, Cheng YJ, Liu LJ, Sara JD, Cao ZY, Zheng WP, Zhang TS, Han HJ, Yang ZY, Zhang Y, Wang FL, Pan RY, Huang JL, Wu LL, Zhang M, Wei YX..What is the association of hypothyroidism with risks of cardiovascular events and mortality? A meta-analysis of 55 cohort studies involving 1,898,314 participants.. BMC Med. 2017,15（1）:1-15.SCI

11. Zhang M, Guddeti RR, Matsuzawa Y, Sara JD, Kwon TG, Liu Z, Sun T, Lee SJ, Lennon RJ, Bell MR, Schaff HV, Daly RC, Lerman LO, Lerman A*, Locker C*..Left Internal Mammary Artery Versus Coronary Stents: Impact on Downstream Coronary Stenoses and Conduit Patency.. J Am Heart Assoc. 2016,5（9）:120-130.SCI

12. Zhang M, Sara JD, Matsuzawa Y, Gharib H, Bell MR, Gulati R, Lerman LO, Lerman A..Clinical outcomes of patients with hypothyroidism undergoing percutaneous coronary intervention.. Eur Heart J. 2016,37(26):2055-2066.SCI

13.  Zhang M#, Sara JD, Wang FL, Liu LP, Su LX, Zhe J, Wu X, Liu JH*. .Zhang M#, Sara JD, Wang FL, Liu LP, Su LX, Zhe J, Wu X, Liu JH*. Increased plasma BMP-2 levels are associated with atherosclerosis burden and coronary calcification in type 2 diabetic patients. . Cardiovascular diabetology. 2015,14:64:14:64.SCI