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2003年获清华大学生物系学士学位。2008年获美国杜克大学(Duke University)神经生物学系博士学位。2011-2012年作为访问学者在美国麻省理工学院(MIT)麦戈文研究所(McGovernInstitute)进行国际合作研究。获得北京市级人才称号。实验室应用在体电生理、在体光纤记录、光遗传学、神经示踪、行为学等技术,研究强迫症和自闭症的发病机制。研究成果以通讯或第一作者发表在Neuron , CurrentBiology, Journal of Neuroscience, Journal of Psychiatry & Neuroscience等国际一流杂志。
作为负责人,承担国家自然科学基金面上项目,北京市教委-市基金委联合资助科技重点项目等。
1. ZichengYang, Geming Wu, Min Liu, Xiaohong Sun, Qunyuan Xu, Chen Zhang*, Huimeng Lei*. Dysfunction ofOrbitofrontal GABAergic Interneurons Leads to Impaired Reversal Learning in aMouse Model of Obsessive-Compulsive Disorder. Current Biology. 2021, 31(2):381-393.
2. Huimeng Lei*, Juan Lai,Xiaohong Sun, Qunyuan Xu, Guoping Feng*, Lateral orbitofrontal dysfunction inthe Sapap3 knockout mouse model of obsessive–compulsive disorder, Journal of Psychiatry & Neuroscience,2019, 44(2):120-131
3. Huimeng Lei, RichardMooney*, Manipulation of a Central Auditory Representation Shapes Learned VocalOutput, Neuron, 2010, 65(1):122-134
4. Huimeng Lei*, Zhangming Yan,Xiaohong Sun, Yue Zhang, Jianhong Wang, Caihong Ma, Qunyuan Xu , Rui Wang,Erich D. Jarvis, Zhirong Sun*, Axon guidance pathways served as common targetsfor human speech/language evolution and related disorders, Brain and Language. 2017, 174:1-8
5. Hui Chen, HuimengLei*, Qunyuan Xu*, Neuronal activity pattern defects in the striatum inawake mouse model of Parkinson's disease, BehaviouralBrain Research, 2018, 341:135-145
6. Huimeng Lei, RichardMooney*, Lawrence C. Katz, Synaptic Integration of Olfactory Information inMouse Anterior Olfactory Nucleus. Journalof Neuroscience, 2006, 26(46):12023-12032
7. Chuan Wang, Bin Shan, Qiong Wang, Qunyuan Xu,Hailin Zhang, Huimeng Lei*, Fusion of Ssm6a with a protein scaffold retains selectivity on NaV1.7 and improves its therapeutic potential against chronic pain, ChemicalBiology & Drug Design, 2017, 89(6):825-833
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