携手探索生命源头的奥秘

科研项目：

1. 在小鼠生殖衰老过程中NQO2介导儿茶酚胺雌激素对卵巢内环境稳态的损害。国家自然科学基金，2021-2024，面上项目，82071641，55万

2. 小鼠卵母细胞内多位点存在的中心粒成分协同调控纺锤体的组装和非对称性定位的分子机制。国家自然科学基金，2017-2020，面上项目，81671454，60万。

3. δ-Tubulin在小鼠卵母细胞减数分裂中的作用和分子机制研究。北京市自然科学基金，2018-2021，重点项目，7181001，80万

近五年SCI论文（*corresponding author）：

1. Claudia Baumann, Wei Ma,Muthugapatti K Kandasamy, Maria M Viveiros, Rabindranath De La Fuente*. Helicase LSH/Hells regulateskinetochore function, histone H3/Thr3 phosphorylation and centromeretranscription during oocyte meiosis. Nature Communication, 2020; 11(1): 4486.

2. Xiaoyu Liu, Xiaoyun Liu, Dandan Chen, Xiuying Jiang, Wei Ma*. PLD2 regulates microtubule stability and spindle migrationin mouse oocytes during meiotic division.PeerJ, 2017; 5:e3295.

3. Dandan Chen, Xin Li, Xiaoyun Liu, Xiaoyu Liu, Xiuying Jiang, Juan Du, QianWang, Yuanjing Liang*, Wei Ma*. NQO2 inhibition relievesreactive oxygen species effects on mouse oocyte meiotic maturation and embryodevelopment. Biology of Reproduction,2017; 97(4): 598-611

4. Xin Li, Yubo Zhu, Yan Cao, Qian Wang, Juan Du, Jianhui Tian, Yuanjing Liang*, WeiMa*. LIMK activity is required for microtubule organizing center (MTOC) positioning in mouse oocyte meiosis. Reproduction, Fertility and Development, 2017; 29(4): 791-804.

5. Nana Zhang, Xiuhong Li, Xiaoyu Liu, Yan Cao, Dandan Chen, Xiaoyun Liu, Qian Wang,Juan Du, Jing Weng*, Wei Ma*. p21-activated kinase 1activity is required for histone H3 Ser10 phosphorylation and chromatincondensation in mouse oocyte meiosis. Reproduction, Fertility and Development, 2017; 29(7): 1287-1296