已毕业博士生，获得国家自然科学基金青年基金项目2项。

1. 国家自然科学基金面上项目 （82170541） Glcα1,2Galβ1-糖基化修饰: IL-2/IL-2R介导JAK-STAT信号途径激活的关键？2022.01- 2025.12  

2. 国家自然科学基金面上项目（81271901）乙肝病毒颗粒组装的质量控制：aer61辅助糖型分选 2013.1-2016.12

3. 国家自然科学基金面上项目（81071411）糖基因C3orf39:肝星状细胞增殖调控的新靶点？ 2011.1-2013.12

4. 国家自然科学基金面上项目（30872243） 新糖基因Glt25D2克隆及在HBV糖基化修饰过程中的作用研究2009.1-2011.12

5. 国家自然科学基金面上项目（30671875） 肝星状细胞血管紧张素II功能相关新基因的克隆表达及功能研究 2007.1-2009.12

6. 国家重点研发计划项目子课题（2018YFC1705700） ：茵芪三黄解毒汤治疗乙肝相关性代偿期肝硬化的临床研究 2018.12-2021.12

7. 北京市自然科学基金 （7202071）GlCα1，2Galβ1糖基化修饰对CD4+T细胞亚群增殖的影响及在肝损伤中的作用 2020.1-2022.12

8. 北京市医院管理中心消化内科学科协同发展中心专项（XXZ04）：食管胃静脉曲张出血风险评价算法的建立及应用 2018.06-2022.06 

9. 北京市自然科学基金（7152073） GlCα1，2Galβ1糖基化修饰对肝细胞脂肪变代谢调控的分子机制研究 2015.1-2017.12

10.  首都临床特色应用研究（Z181100001718084）GP73对NASH的临床诊断价值研究 2018.06-2021.05

11. 首都临床特色应用研究（Z141107002514132）GP73对HBV相关早期肝癌的预警诊断价值研究  2014.06-2017.06 

12.  首都卫生发展科研专项项目（2014-2-2171）：慢性HBV感染肝纤维化分期诊断新算法模型的建立及应用 2014.06-2017.05 

所带领的课题组先后获得国家自然科学基金面上项目资助8项；北京市自然科学基金面上项目2项；首都临床特色研究项目2项；首都医学发展基金1项；其他横、纵向课题10余项。

获得国家发明专利2项；PCT专利2项。主要SCI论文列表。

1.      Shu Y, He L, Gao M, Xiao F,Yang J, Wang S, Wei H, Zhang F, Wei H. EOGT Correlated With ImmuneInfiltration: A Candidate Prognostic Biomarker for Hepatocellular Carcinoma.  Front Immunol. 2022;12:780509.

2.      Ma JL, Li P, Jiang L, Wei HS. Long-termoutcomes of hepatectomy or radiofrequency ablation associated with splenectomyfor the treatment of hepatocellular carcinoma and esophagogastric varicealbleeding. Asian J Surg. 2022;45(8):1607-1609.

3.      Xiao F, Gao M, Yang J, He L,Wei H. FAM172A Deletion May Enhance Hepatic Steatosis by Promoting ER Stress. DigDis Sci. 2021;66(9):3054-3061.

4.      Ma JL, He LL, Li P, Jiang L,Wei HS. Prognosis of endotherapy versus splenectomy and devascularization forvariceal bleeding in patients with hepatitis B-related cirrhosis. Surg Endosc.2021;35(6):2620-2628.

5.      Yang J, He L, Gao M, Xiao F,Zhang F, Wang S, Shu Y, Ye X, Qu W, Li L, Wei H. Collagen β(1-O) galactosyltransferase2 deficiency contributes to lipodystrophy and aggravates NAFLD related to HMWadiponectin in mice. Metabolism. 2021;120:154777.

6.      He L, Ye X, Gao M, Yang J, MaJ, Xiao F, Wei H. Down-regulation of GLT25D1 inhibited collagen secretion andinvolved in liver fibrogenesis. Gene. 2020;729:144233.

7.      Zhang X, Guo L, Zhang X, Xu L,Tian Y, Fan Z, Wei H, Zhang J, Ren F. GLT25D2 Is Critical for InflammatoryImmune Response to Promote Acetaminophen-Induced Hepatotoxicity by AutophagyPathway. Front Pharmacol. 2020;11:01187.

8.      Ma JL, He LL, Jiang Y, Yang JR,Li P, Zang Y, Wei HS. New model predicting gastroesophageal varices andvariceal hemorrhage in patients with chronic liver disease. Ann Hepatol. 2020;19(3):287-294.

9.      Hao X, Gao M, He L, Ye X, YangJ, Zhang F, Liu R, Wei H. Deficiency of O-linked-glycosylation regulatesactivation of T cells and aggravates Concanavalin A-induced liver injury. Toxicology.2020;433-434:152411.

10.   Ma JL, He LL, Li P, Jiang Y, HuJL, Zhou YL, Liang XX, Wei HS. Clinical Features and Outcomes of RepeatedEndoscopic Therapy for Esophagogastric Variceal Hemorrhage in CirrhoticPatients: Ten-Year Real-World Analysis.Gastroenterol Res Pract. 2020;2020:5747563.

11.   Gao M, Li X, He L, Yang J, YeX, Xiao F, Wei H. Diammonium Glycyrrhizinate Mitigates Liver Injury ViaInhibiting Proliferation Of NKT Cells And Promoting Proliferation Of Tregs. DrugDes Devel Ther. 2019;13:3579-3589.

12.   Zhao H, Wang Y, Liu Y, Hao X,Wei H, Xie W. The Effect of Protein FAM172A on Proliferation in HepG2 Cells andInvestigation of the Possible Molecular Mechanism. Anal Cell Pathol (Amst).2019;2019:5901083.

13.   He L, Li P, Jiang Y, Hu J, MaJ, Ye X, Yang J, Zhou Y, Liang X, Ai Z, Lin Y, Wei H. A new algorithm forpredicting long-term survival in chronic hepatitis B patients with varicealbleeding after endoscopic therapy. Dig Liver Dis. 2019;51(8):1166-1171.

14.   He L, Ye X, Ma J, Li P, JiangY, Hu J, Yang J, Zhou Y, Liang X, Lin Y, Wei H. Antiviral therapy reducesrebleeding rate in patients with hepatitis B-related cirrhosis with acutevariceal bleeding after endotherapy. BMC Gastroenterol. 2019;19(1):101

15.   Ma J, Li P, Jiang Y, Hu J, WeiH. Acute variceal bleeding in patients with primary myelofibrosis successfullytreated with endoscopic histoacryl injection. Turk J Gastroenterol. 2018 Nov19. doi: 10.5152/tjg.2018.18324.

16.   Hao X, Li Y, Wang J, Ma J, ZhaoS, Ye X, He L, Yang J, Gao M, Xiao F, Wei H. Deficient O-GlcNAc GlycosylationImpairs Regulatory T Cell Differentiation and Notch Signaling in AutoimmuneHepatitis. Front Immunol. 2018;9:2089.

17.   Zhang MK, Ma HM, Zhang J, SongXC, Ye XH, Li YF, Zhang YF, He LL, Wei HS, Li X. Deletion of the C6orf120 genewith unknown function ameliorates autoimmune hepatitis induced by concanavalinA. Cell Immunol. 2018;331:9-15.

18.   Jiang Y, Hu J, Li P, Jiang W,Liang W, Wei H. A Retrospective Analysis of Cyanoacrylate Injection versusHemoclip Placement for Bleeding Dieulafoy's Lesion in Duodenum. GastroenterolRes Pract. 2018;2018:3208690.

19.   Hao X, Liu R, Zhang Y, Li Y, HeQ, Huang Y, Jiang Y, Ma J, Li P, Wei H. Glt25d2 Knockout Directly IncreasesCD25+CD69- but Decreases CD25-CD69+ Subset Proliferation and is Involved inConcanavalin-Induced Hepatitis.  CellPhysiol Biochem. 2018;50(3):1186-1200.

20.   Ye X, He L, Ma J, Li Y, ZhangM, Yang J, Zhang J, Xiao F, Wei H. Downregulation of Glt25d1 aggravates carbontetrachloride‑induced acute hepatic injury throughactivation of the TGF‑β1/Smad2signaling pathway. Mol Med Rep. 2018 Oct;18(4):3611-3618.

21.   Yang Q, Wang J, Liu R, Wang Z,Li Y, Zhang Y, Hao X, Huang Y, Xie W, Wei H. Amelioration of concanavalinA-induced autoimmune hepatitis by magnesium isoglycyrrhizinate throughinhibition of CD4(+)CD25(-)CD69(+) subset proliferation. Drug Des Devel Ther.2016;10:443-53.

22.   Qiao Y, Chen J, Li X, Wei H,Xiao F, Chang L, Zhang R, Hao X, Wei H. Serum gp73 is also a biomarker fordiagnosing cirrhosis in population with chronic HBV infection. Clin Biochem.2014;47(16-17):216-22.

23.   Wei H, Zhang J, Li H, Ren H,Hao X, Huang Y. GP73, a new marker for diagnosing HBV-ACLF in population withchronic HBV infections. Diagn Microbiol Infect Dis. 2014;79(1):19-24.

24.   Wei H, Li B, Zhang R, Hao X,Huang Y, Qiao Y, Hou J, Li X, Li X. Serum GP73, a marker for evaluatingprogression in patients with chronic HBV infections. PLoS One.2013;8(2):e53862.

25.   Fan X, Chuan S, Hongshan W. ProteinO glycosylation regulates activation of hepatic stellate cells. Inflammation.2013;36(6):1248-52.

26.   Wei H, Hao X, Li B, Li X, HouJ, Qiao Y, Zhang R, Li X. GP73 is a potential marker for evaluating AIDSprogression and antiretroviral therapy efficacy. Mol Biol Rep. 2013;40(11):6397-405.

27.   Wei HS, Wei HL, Zhao F, ZhongLP, Zhan YT. Glycosyltransferase GLT8D2 positively regulates ApoB100 proteinexpression in hepatocytes. Int J Mol Sci. 2013;14(11):21435-46.

28.   Fan X, Fang D, Bin D, XueyongL, Jun C, Hongshan W. Serum levels of surface large envelope proteins:prognostic markers for hepatitis B e antigen-negative patients with adefovirdipivoxil treatment. Antivir Ther. 2009;14(8):1149-56.