以推进中国的神经眼科学科建设为使命，努力提高神经眼科疾病诊断和治疗水平，培养德才兼备、医术精湛的多学科融合团队，不断研发国际一流的高水平研究成果，加强国际合作和交流，实现与重点学科的协同、可持续发展。

，

国家自然科学基金 面上项目，82071312 一种神经保护筛选研究新模型的建立-恒河猴眼动脉缺血/再灌注模型，2021.01-2024.12，55万，主持

（2）科技部国家重点研发计划重大慢病防控专项子课题，2017YFC1307903，症状性颅内外动脉粥样硬化性狭窄人群中整体动脉粥样硬化水平与心血管事件复发相关性研究，2017.07-2020.12，200万元，结题，参加

国家自然科学基金 面上项目，82071312 一种神经保护筛选研究新模型的建立-恒河猴眼动脉缺血/再灌注模型，2021.01-2024.12，55万，主持

（2）科技部国家重点研发计划重大慢病防控专项子课题，2017YFC1307903，症状性颅内外动脉粥样硬化性狭窄人群中整体动脉粥样硬化水平与心血管事件复发相关性研究，2017.07-2020.12，200万元，结题，参加

近五年专利：

1.一种眼底动静脉图像分割方法，装置和设备（202111039014.0）

近五年发表SCI论文：

1.Yuan Gao, Wenbo Zhao, Di Wu, Changhong Ren, XuxiangZhang, Xunming Ji. Cerebral and cardiovascular events in patientswith acute retinal arterial ischemia. 2022, Ready to summit.

2. Yuan Gao, Wenbo Zhao, Di Wu, Wayne Feng, Brain Mac Grory, Marc Fisher,Wenting Guo, Dawei Zhang, Xinjie Su, Xunming Ji, Xuxiang Zhang.Intra-Arterial Thrombolysis for Acute Retinal Ischemia: A Retrospective,Observational, Cohort Study.2022, Ready to summit.

3. Yuan Gao, Ning He, Chuanjie Wu, Wenbo Zhao, Xizhe Wang, ChongChong Song,Wenting Guo, Xuxiang Zhang, Yang Gao, Xunming Ji. The relation of retinal vascular signs andintracranial atherosclerotic stenosis. American Journal of Ophthalmology. 2022, Under review.

4. NingHe, Yang Gao, Yuan Gao, Zemin Shi, ChongChong Song,Yuchen Liu, Jingkai Wang,Xuxiang Zhang, Xunming Ji, Defeng Wang. DR-Net: Dual Refinement Network forRetinal Arteriovenous Vessel Segmentation. IEEE Journal of Biomedical andHealth Informatics. 2022, Under review.

5. Brian Mac Grory, Matthew Schrag, Sven Poli, Chantal JBoisvert, Martin S Spitzer, MaximillianSchultheiss, Max Nedelmann, Shadi Yaghi, Mary Guhwe, Elizabeth E Moore, Hunter R Hewitt, Kelsey M Barter, Taewon Kim, Maomao Chen, Lucas Humayun, Chang Peng, Pratik Y Chhatbar, Patrick Lavin, Xuxiang Zhang, Xiaoning Jiang, Eytan Raz, Shiv Saidha, Junjie Yao, Valérie Biousse, Wuwei Feng.Structural and Functional Imaging of the Retina in Central Retinal ArteryOcclusion-Current Approaches and Future Directions. J Stroke CerebrovascDis, 2021.30(7): p.105828.

6. Di Wu; Jian Chen; Xuxiang Zhang; Roxanne llagan; Yuchuan Ding;Xunming Ji; Selective therapeutic cooling: To maximize benefits and minimizeside effects related to hypothermia, Journal of Cerebral Blood Flow andMetabolism, 2021, 41(11):1-3.

7.Yuan Gao, Di Wu, Dachuan Liu, MitchellHuber,Jian Chen,Xizhe Wang,Kui Lv,

Xiaodu He, Huiqing Yang, Changhong Ren,YuchuanDing, Xunming Ji, Xuxiang Zhang*.Novel acute retinalartery ischemia and reperfusion model in nonhuman primates.Stroke,2020;51:2568-2572.

8.Yuan Gao, Di Wu, XuxiangZhang*. Letter to Gadolinium Leakage in Ocular Structures Is Common in LacunarInfarction. Stroke,2019 ;50(4):114.

9.Changhong Ren, Hang Wu,Dongjie Li, Yong Yang, Yuan Gao, Yunneng Jizhang, Dachuan Liu, Xunming Ji, XuxiangZhang*. Remote ischemic conditioning protects diabetic retinopathy instreptozotocin-induced diabetic rats via anti-inflammation and antioxidation.Aging and Disease,2018,6(9):1122-1133.

10. Ding J, Zhou D, GengT, Pan L, Ya J, Wang Z, Hu Y, Ding Y, Zhang X*, Meng R*. To predict visual deteriorationaccording to the degree of intracranial hypertension in patients with cerebralvenous sinus thrombosis. Eur Neurol,2018;80(1-2):28-33.

11.Wang L, Duan J, BianT, Meng R, Wu L, Zhang Z, Zhang X, Wang C, Ji X. Inflammation is correlated with severity and outcome of cerebral venousthrombosis.

J Neuroinflammation, 2018, 26;15(1):329.

12.Hu Y, Meng R, Zhang X, Guo L, Li S, Wu Y,Duan J, Ding Y, Ji X. Serum neuronspecific enolase may be a marker to predict the severity and outcome ofcerebral venous thrombosis. J Neurol, 2018;265(1):46-51.

13.Liu D, Li Z, Zhang X, Zhao L, Jia J, SunF, Wang Y, Ma D, Wei W. Assessment ofintracranial pressure with ultrasonographic retrobulbar optic nerve sheathdiameter measurement.BMC Neurol,2017,29;17(1):188.