导师风采
韩如泉
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个人信息

Personal Information

  • 主任医师
  • 导师类别:博士生导师
  • 性别: 男
  • 学历:博士研究生
  • 学位:博士

联系方式

Contact Information

  • 所属院系:附属北京天坛医院
  • 所属专业: 麻醉学
  • 邮箱 : hanrq666@aliyun.com
  • 工作电话 : -

个人简介

Personal Profile

韩如泉,现任首都医科大学附属北京天坛医院麻醉科主任,主任医师,教授,博士研究生导师。2006.8-2007.9受教育部国家留学基金资助前往美国斯坦福大学医学院麻醉科RonaGiffard实验室工作1年。10余年来,先后以项目负责人身份承担各级科研项目10余项,其中包括北京市科委科技新星、北京市卫生局“215”人才学科骨干、北京市科委首都特色课题、首都医学发展基金重点项目、北京市医院管理局重点医学专业-神经外科麻醉、北京市自然项目、国家自然科学基金等,并作为子课题负责人参与科技部国家重点研发计划重大慢性非传染性疾病防控研究,累计可支配科研经费800余万元。主要研究方向为神经外科麻醉、围术期神经功能监测与保护等。目前为止,以第一或责任作者在国内外专业期刊发表论文200余篇,累计影响因子69.701,被引次数158次。主编主译专业书籍6部,包括《神经外科麻醉手册》、《临床麻醉系列丛书·神经外科麻醉分册》、《Cottrell&Young神经外科麻醉学》、《围术期神经系统监测》、《神经外科麻醉学(第三版)》等。现任中华医学会麻醉学分会神经外科麻醉学组副组长、中国医师协会麻醉学医师分会委员、北京医学会麻醉学分会副主任委员兼秘书长、北京医师协会麻醉专科医师分会副会长、北京生理科学会副理事长、首都医科大学麻醉学系副主任、《中华麻醉学杂志》、《国际麻醉学与复苏杂志》、《临床麻醉学杂志》编委等职。


  • 研究方向Research Directions
麻醉神经科学
2. 机电结构优化与控制 研究内容:在对机电结构进行分析和优化的基础上,运用控制理论进行结构参数的调整,使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容:以仿生结构为研究对象,运用连续体结构拓扑优化设计理论和方法,对多相仿生结构(机构)材料进行2. 机电结构优化与控制 研究内容:在对机电结构进行分析和优化的基础上,运用控制理论进行结构参数的调整,使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容:以仿生结构为研究对象,运用连续体结构拓扑优化设计理论和方法,对多相仿生结构(机构)材料进行整体布局设计。 整体布局设计。
项目情况

1.   首都特色临床应用研究课题—颈动脉内膜剥脱术围术期脑缺血监测及预警阈值研究。经费15万元。负责人。

2.   首都医学发展基金重点攻关项目(2016-1-20410)-麻醉深度对颅脑肿瘤临床转归影响的研究,2016/01-2018/12。科研经费150万元。负责人。

3.   北京市医院管理局“扬帆”计划重点学科建设(ZYLX201708)-神经外科麻醉,2017/01-2019/12。科研经费300万元。项目负责人。

4.  北京市医院管理局第二批登峰计划入选团队(DFL20180502),2018/01-2021/12。科研经费94万元。项目负责人。

5.   北京市自然科学基金(7192055):基于功能磁共振下胶质瘤患者神经认知功能机制的研究,2019/01-2021/12,经费20万元。课题负责人

6.   北京市科委科技计划项目(Z19110700660000):神经外科麻醉管理与策略优化研究,2019/09-2023/08,经费120万元。在研,课题负责人

7.   首都医学发展基金(2021)-星状神经节阻滞预防蛛网膜下腔出血后脑血管痉挛的研究,2022/01-2024/12。科研经费40万元。项目负责人。

8. 国家自然科学基金面上项目(82271284)-基于同步EEG-fMRI采集的丙泊酚麻醉脑网络连接机制研究,2023/01-2026/12。科研经费52万元。项目负责人。

9.  北京市卫生健康委员会北京市卫生健康科技成果和适宜技术推广项目(技术成果类)(BHTPP2022)-围术期多模态脑功能监测的应用,2022/11-2024/05。科研经费5万元。项目负责人。

10.北京市教委-市自然重点项目(KZ2023002544)-丙泊酚麻醉与慢性意识障碍的意识特异性脑网络研究,2023/01-2025/12。科研经费80万元。项目负责人。


科研项目

国家自然科学基金面上项目(82271284)-基于同步EEG-fMRI采集的丙泊酚麻醉脑网络连接机制研究,2023/01-2026/12。科研经费52万元。项目负责人。

北京市卫生健康委员会北京市卫生健康科技成果和适宜技术推广项目(技术成果类)(BHTPP2022)-围术期多模态脑功能监测的应用,2022/11-2024/05。科研经费5万元。项目负责人。

北京市教委-市自然重点项目(KZ2023002544)-丙泊酚麻醉与慢性意识障碍的意识特异性脑网络研究,2023/01-2025/12。科研经费80万元。项目负责人。


研究成果

1.      Zhang Z, Wang X, Zhang K, Wu Y, Liang F, WangA, Han R. Safety and Efficacy of Neuroprotective Agents as Adjunctive Therapiesfor Reperfusion in the Treatment of Acute Ischemic Stroke: A Systematic Reviewand Meta-analysis of Randomized Controlled Trials. J Neurosurg Anesthesiol.2025 Feb 6. doi: 10.1097/ANA.0000000000001029. Epub ahead of print. PMID:39912307.

2.      Sun Y, Pu Z, Zhao H, Deng Y, Zhang J, Li S,Jiang Y, Sun M, Zhu J, Alam A, Ma D, Han R. Vitamin D can mitigatesepsis-associated neurodegeneration by inhibiting exogenous histone-inducedpyroptosis and ferroptosis: Implications for brain protection and cognitivepreservation. Brain Behav Immun. 2025 Feb;124:40-54. doi:10.1016/j.bbi.2024.11.019. Epub 2024 Nov 19. PMID: 39566666.

3.      Hu Z, Zhang K, Wu Y, Wang X, Zhang Z, Hou X,Jian M, Wang Y, Liu H, Wang A, Han R, Liang F. Oxygenation targets forendovascular therapy in acute ischemic stroke patients (Oxy-TARGET): protocolfor a single-centre, open-label randomised controlled trial. BMJ Open. 2025 Jan4;15(1):e086234. doi: 10.1136/bmjopen-2024-086234. PMID: 39755573; PMCID:PMC11751949.

4.      Wang X, Liang F, Wu Y, Jia B, Zhang X, Jian M,Liu H, Wang A, Miao Z, Han R. Anesthesia on Clinical Outcomes in an ExtendedTime Window During Endovascular Stroke Therapy: Exploratory Analysis of theANGEL-ACT Registry. J Neurosurg Anesthesiol. 2025 Jan 1;37(1):64-69. doi:10.1097/ANA.0000000000000959. Epub 2024 Mar 28. PMID: 38546201.

5.      Zhang K, Wang X, Wu Y, Liang F, Hou X, Zhang Z,Wang A, Liu L, Han R. Intensive Versus Standard Blood Pressure Management afterEndovascular Therapy for Acute Ischemic Stroke: A Systematic Review andMeta-analysis. J Neurosurg Anesthesiol. 2025 Jan 1;37(1):20-30. doi:10.1097/ANA.0000000000000961. Epub 2024 Apr 1. PMID: 38557945.

6.      Wang X, Yang W, Jian M, Liang Y, Yang Z, ChenY, Ma B, Wang C, Hou Z, Deng Z, Liu H, Xie J, Han R. The characteristics ofauditorial event-related potential under propofol sedation associated withpreoperative cognitive performance in glioma patients. Front Neurosci. 2024 Nov14;18:1431406. doi: 10.3389/fnins.2024.1431406. PMID: 39610867; PMCID:PMC11603416.

7.      Zhang K, Liang F, Wu Y, Wang X, Hou X, Zhang Z,Yu Y, Wang Y, Han R. Associations of arterial oxygen partial pressure with all‑causemortality in critically ill ischemic stroke patients: a retrospective cohortstudy from MIMIC IV 2.2. BMC Anesthesiol. 2024 Oct 4;24(1):355. doi:10.1186/s12871-024-02750-z. PMID: 39367296; PMCID: PMC11451185.

8.      Wang X, Liang F, Wu Y, Jia B, Wang A, Zhang X,Zhang K, Hou X, Jian M, Wang Y, Liu H, Miao Z, Han R. Development andValidation of a Two-step Model to Predict Outcomes After Endovascular Treatmentfor Patients With Acute Ischemic Stroke. J Neurosurg Anesthesiol. 2024 Sep 18.doi: 10.1097/ANA.0000000000001008. Epub ahead of print. PMID: 39291867.

9.      Zhou Y, Sun W, Fu Y, Wang J, Fan J, Liang Y,Jia W, Han R. Effect of esketamine combined with pregabalin on acutepostsurgical pain in patients who underwent resection of spinal neoplasms: arandomized controlled trial. Pain. 2024 Sep 1;165(9):e96-e105. doi:10.1097/j.pain.0000000000003211. Epub 2024 Mar 15. PMID: 38501980.

10.   Liang F, Zhang K, Wu Y, Wang X, Hou X, Yu Y,Wang Y, Wang M, Pan Y, Huo X, Han R, Miao Z. Anaesthesia modality onendovascular therapy outcomes in patients with large infarcts: a post hocanalysis of the ANGEL-ASPECT trial. Stroke Vasc Neurol. 2024 Aug19:svn-2024-003320. doi: 10.1136/svn-2024-003320. Epub ahead of print. PMID:39160092.

11.   MaJ, Wang J, Li Y, Fu Y, Li Y, Qiao H, Han R. Effect of desflurane anesthesia onflash visual evoked potential monitoring in patients undergoing spine surgery:study protocol for a randomized controlled trial. Trials. 2024 Jun 6;25(1):362.doi: 10.1186/s13063-024-08211-9. PMID: 38840210; PMCID: PMC11155073.

12.   YangW, Jian M, Wang X, Zhou Y, Liang Y, Chen Y, Li Y, Li K, Ma B, Liu H, Han R.Dynamic Cortical Connectivity During Propofol Sedation in Glioma Patients. JNeurosurg Anesthesiol. 2024 Apr 5. doi: 10.1097/ANA.0000000000000964. Epubahead of print. PMID: 38577956.

13.   LeleAV, Shiferaw AA, Theard MA, Vavilala MS, Tavares C, Han R, Assefa D, DagneAlemu M, Mahajan C, Tandon MS, Karmarkar NV, Singhal V, Lamsal R, Athiraman U;Global-SAH project collaborators. A Global Review of the Perioperative Care ofPatients With Aneurysmal Subarachnoid Hemorrhage Undergoing MicrosurgicalRepair of Ruptured Intracerebral Aneurysm. J Neurosurg Anesthesiol. 2024 Apr1;36(2):164-171. doi: 10.1097/ANA.0000000000000913. Epub 2023 Apr 19. PMID:37294597; PMCID: PMC10584987.

14.   YuY, Fu Y, Li W, Sun T, Cheng C, Chong Y, Han R, Cui W. Red blood celltransfusion in neurocritical patients: a systematic review and meta-analysis.BMC Anesthesiol. 2024 Mar 19;24(1):106. doi: 10.1186/s12871-024-02487-9. PMID:38504153; PMCID: PMC10949741.

15.   Wang X, Wu Y, Liang F, Gu H,Jian M, Wang Y, Liu H, Han R. General anesthesia versus nongeneral anesthesiaduring endovascular therapy for acute ischemic stroke: A systematic review andmeta-analysis. J Evid Based Med. 2023 Dec;16(4):477-484. doi:10.1111/jebm.12569. Epub 2023 Dec 21. PMID: 38130029.

16.   Wu Y, Lin F, Bai Y, Liang F,Wang X, Wang B, Jian M, Wang Y, Liu H, Wang A, Chen X, Han R. Early stellateganglion block for improvement of postoperative cerebral blood flow velocityafter aneurysmal subarachnoid hemorrhage: results of a pilot randomizedcontrolled trial. J Neurosurg. 2023 Apr 28;139(5):1339-1347. doi:10.3171/2023.3.JNS222567. PMID: 37119094.

17.   Liu Y, Xiao S, Yang H, Lv X,Hou A, Ma Y, Jiang Y, Duan C, Mi W; CAPOPS Group. Postoperative pain-relatedoutcomes and perioperative pain management in China: a population-based study.Lancet Reg Health West Pac. 2023 Jun 10;39:100822. doi:10.1016/j.lanwpc.2023.100822. PMID: 37927993; PMCID: PMC10625022.

18.   Wang X, Liang F, Wu Y, Jia B,Zhang Y, Jian M, Liu H, Wang A, Han R, Miao Z. Association of Admission Glucoseand Outcomes After Endovascular Treatment for Acute Stroke: Data From theANGEL-ACT Registry. J Neurosurg Anesthesiol. 2023 Aug 25. doi: 10.1097/ANA.0000000000000937.Epub ahead of print. PMID: 37624771.

19.   Jian M, Liu H, Liang F, Ma B,Wang L, Zhou Y, Qiao H, Han R, Wang C. Effect of intraoperative musclerelaxation reversal on the success rate of motor evoked potential recording inpatients undergoing spinal surgery: a randomized controlled trial. BMCAnesthesiol. 2023 Aug 25;23(1):290. doi: 10.1186/s12871-023-02211-z. PMID:37626303; PMCID: PMC10464330.

20.   WangX, Wu Y, Liang F, Jian M, Yu Y, Wang Y, Han R. General Anesthesia VersusNongeneral Anesthesia for Patients With Acute Posterior Circulation StrokeUndergoing Endovascular Therapy: A Systematic Review and Meta-analysis. JNeurosurg Anesthesiol. 2023 Jul 1;35(3):274-283. doi:10.1097/ANA.0000000000000873. Epub 2022 Sep 26. PMID: 36156053.

21.   Li A, Liu H, Lei X, He Y, WuQ, Yan Y, Zhou X, Tian X, Peng Y, Huang S, Li K, Wang M, Sun Y, Yan H, Zhang C,He S, Han R, Wang X, Liu B. Hierarchical fluctuation shapes a dynamic flowlinked to states of consciousness. Nat Commun. 2023 Jun 5;14(1):3238. doi:10.1038/s41467-023-38972-x. PMID: 37277338; PMCID: PMC10241811.

22.   Si J, Li M, Zhang X, Han R, JiX, Jiang T. Cerebral tissue oximeter suitable for real-time regional oxygensaturation monitoring in multiple clinical settings. Cogn Neurodyn. 2023Jun;17(3):563-574. doi: 10.1007/s11571-022-09847-6. Epub 2022 Aug 18. PMID:37265661; PMCID: PMC10229493.

23.   Xie S, Shi L, Xiong W, Chen L,Li X, Tong Y, Yang W, Wang A, Zhang J, Han R. Choice of anaesthesia inmicroelectrode recording-guided deep-brain stimulation for Parkinson's disease(CHAMPION): study protocol for a single-centre, open-label, non-inferiorityrandomised controlled trial. BMJ Open. 2023 May 30;13(5):e071726. doi:10.1136/bmjopen-2023-071726. PMID: 37253497.

24.   Wang J, Wang X, Liu H, Han R.Effect of butorphanol on visceral pain in patients undergoing gastrointestinalendoscopy: a randomized controlled trial. BMC Anesthesiol. 2023 Mar28;23(1):93. doi: 10.1186/s12871-023-02053-9. PMID: 36977981; PMCID:PMC10044711.

25.   Yang W, Wang X, Liu H, Li M,Liu X, Lin N, Hu L, Han R. Electroencephalography characteristics of patientswith supratentorial glioma in different consciousness states induced bypropofol. Neurosci Lett. 2023 May 2;808:137284. doi:10.1016/j.neulet.2023.137284. Epub ahead of print. PMID: 37142112.

26.   Liu F, Zhang W, Zhao Z, Xu X,Jian M, Han R. Effect of driving pressure on early postoperative lung gasdistribution in supratentorial craniotomy: a randomized controlled trial. BMCAnesthesiol. 2023 May 22;23(1):176. doi: 10.1186/s12871-023-02144-7. PMID:37217882; PMCID: PMC10201743.

27.   SunW, Zhou Y, Wang J, Fu Y, Fan J, Cui Y, Wu Y, Wang L, Yu Y, Han R. Effects ofKetamine on Chronic Postsurgical Pain in Patients Undergoing Surgery: ASystematic Review and Meta-analysis. Pain Physician. 2023 May;26(3):E111-E122.PMID: 37192226.

28.   Sun W, Wang J, Wang J, Fan J,Zhou Y, Wang Y, Han R. Esketamine combined with pregabalin on acutepostoperative pain in patients undergoing resection of spinal neoplasms: studyprotocol for a randomized controlled trial. Trials. 2023 Feb 25;24(1):144. doi:10.1186/s13063-023-07178-3. PMID: 36841794; PMCID: PMC9960454.

29.   GeQ, Wang Y, Zhuang Y, Li Q, Han R, Guo W, He J. Opioid-induced short-termconsciousness improvement in patients with disorders of consciousness. FrontNeurosci. 2023 Feb 3;17:1117655. doi: 10.3389/fnins.2023.1117655. PMID:36816138; PMCID: PMC9936155.

30.   JiangZ, Wu Y, Liang F, Jian M, Liu H, Mei H, Han R. Brain relaxation usingdesflurane anesthesia and total intravenous anesthesia in patients undergoingcraniotomy for supratentorial tumors: a randomized controlled study. BMCAnesthesiol. 2023 Jan 10;23(1):15. doi: 10.1186/s12871-023-01970-z. PMID:36624384; PMCID: PMC9830805.

31.   LiangF, Wu Y, Wang X, Yan L, Zhang S, Jian M, Liu H, Wang A, Wang F, Han R; CANVASII Group. General Anesthesia vs Conscious Sedation for Endovascular Treatmentin Patients With Posterior Circulation Acute Ischemic Stroke: An ExploratoryRandomized Clinical Trial. JAMA Neurol. 2023 Jan 1;80(1):64-72. doi:10.1001/jamaneurol.2022.3018. PMID: 36156704; PMCID: PMC9513708.

32.   ZhangW, Liu F, Zhao Z, Shao C, Xu X, Ma J, Han R. Driving pressure-guidedventilation improves homogeneity in lung gas distribution for gynecologicallaparoscopy: a randomized controlled trial. Sci Rep. 2022 Dec 15;12(1):21687.doi: 10.1038/s41598-022-26144-8. PMID: 36522433; PMCID: PMC9755264.

33.   ZouL, Han R. Inflammatory Response and Immune Regulation in Brain-HeartInteraction after Stroke. Cardiovasc Ther. 2022 Nov 16;2022:2406122. doi:10.1155/2022/2406122. PMID: 36474712; PMCID: PMC9683992.

34.   JingL, Wu Y, Liang F, Jian M, Bai Y, Wang Y, Liu H, Wang A, Chen X, Han R. Effectof early stellate ganglion block in cerebral vasospasm after aneurysmalsubarachnoid hemorrhage (BLOCK-CVS): study protocol for a randomized controlledtrial. Trials. 2022 Nov 4;23(1):922. doi: 10.1186/s13063-022-06867-9. PMID:36333751; PMCID: PMC9636713.

35.   FuY, Yu Y, Cui Y, Wang J, Ma B, Jian M, Yao J, Jing L, Bai J, Han R. Factorsassociated with artificial airway retention after skull base chordomaresection: A retrospective cohort study. Front Neurol. 2022 Sep 9;13:992308.doi: 10.3389/fneur.2022.992308. PMID: 36158950; PMCID: PMC9500194.

36.   ZhangY, Yue H, Qin Y, Wang J, Zhao C, Cheng M, Han B, Han R, Cui W. Effect ofSufentanil Combined with Gabapentin on Acute Postoperative Pain in Patients UndergoingIntraspinal Tumor Resection: Study Protocol for a Randomized Controlled Trial.J Pain Res. 2022 Sep 1;15:2619-2628. doi: 10.2147/JPR.S374898. PMID: 36072908;PMCID: PMC9444033.

37.   Wang X,Wang X, Liang F, Yu Y, Han R. Safety and efficacy of intravenous or topicaltranexamic acid administration in surgery: a protocol for a systematic reviewand network meta-analysis. BMJ Open. 2022 May 9;12(5):e058093. doi:10.1136/bmjopen-2021-058093. PMID: 35534082; PMCID: PMC9086642.

38.   Jian M,Ma B, Liu H, Wang C, Liang F, Zhou Y, Qiao H, Han R. Effect of intraoperativemuscle relaxation reversal on the success rate of motor-evoked potentialrecording in patients undergoing spinal surgery: study protocol for arandomised controlled trial. BMJ Open. 2022 May 2;12(5):e056571. doi:10.1136/bmjopen-2021-056571. PMID: 35501072; PMCID: PMC9062813.

39.   Ma J,Xiong W, Guo D, Wang A, Qiao H, Han R. Effects of Sevoflurane-Propofol-BalancedAnesthesia on Flash Visual Evoked Potential Monitoring in Spine Surgery: ARandomized Noninferiority Trial. Anesth Analg. 2022 May 1;134(5):1054-1061.doi: 10.1213/ANE.0000000000005742. PMID: 34543246.

40.   ZhouY, Ma B, Sun W, Wang J, Fu Y, Wang A, Wang G, Han R. Effect of esketamine onperioperative depressive symptoms in major surgery patients (PASSION II): studyprotocol for a randomised controlled trial. BMJ Open. 2022 Apr26;12(4):e056713. doi: 10.1136/bmjopen-2021-056713. PMID: 35473735; PMCID:PMC9045044.

41.   LiuH, Hu K, Peng Y, Tian X, Wang M, Ma B, Wu Y, Sun W, Liu B, Li A, Han R. Dynamicreconfiguration of human brain networks across altered states of consciousness.Behav Brain Res. 2022 Feb 15;419:113685. doi: 10.1016/j.bbr.2021.113685. Epub2021 Nov 26. PMID: 34838931.

42.   LiJ, Zhao Y, Yan X, Li R, Zhang X, Zeng M, Dong J, Li S, Peng Y, Han R.Perioperative Risk Factors Associated With Acute Kidney Injury in PatientsAfter Brain Tumor Resection. J Neurosurg Anesthesiol. 2022 Jan 1;34(1):51-56.doi: 10.1097/ANA.0000000000000716. PMID: 32658102.

43.   YuB, Peng Y, Qiao H, Liu B, Wang M, Yang X, Han R. The Application of RegionalCerebral Oxygenation Monitoring in the Prediction of Cerebral HypoperfusionDuring Carotid Endarterectomy. J Neurosurg Anesthesiol. 2022 Jan 1;34(1):29-34.doi: 10.1097/ANA.0000000000000690. PMID: 32379101.

44.   FanYF, Shen M, Wang XX, Liu XY, Peng YM, Gao PY, Han RQ. The Reliability ofMeasuring Early Brain Edema with Computed Tomography. Curr Med Imaging.2022;18(8):830-836. doi: 10.2174/1573405617666211208124839. PMID: 34879812.

45.   YuY, Cui WH, Cheng C, Lu Y, Zhang Q, Han RQ. Association betweenneutrophil-to-lymphocyte ratio and major postoperative complications aftercarotid endarterectomy: A retrospective cohort study. World J Clin Cases. 2021Dec 16;9(35):10816-10827. doi: 10.12998/wjcc.v9.i35.10816. PMID: 35047593;PMCID: PMC8678856.

46.   Zhou Y,Sun W, Zhang G, Wang A, Lin S, Chan MTV, Peng Y, Wang G, Han R. KetamineAlleviates Depressive Symptoms in Patients Undergoing Intracranial TumorResection: A Randomized Controlled Trial. Anesth Analg. 2021 Dec1;133(6):1588-1597. doi: 10.1213/ANE.0000000000005752. PMID: 34633992.

47.   EveredLA, Chan MTV, Han R, Chu MHM, Cheng BP, Scott DA, Pryor KO, Sessler DI, VeselisR, Frampton C, Sumner M, Ayeni A, Myles PS, Campbell D, Leslie K, Short TG.Anaesthetic depth and delirium after major surgery: a randomised clinicaltrial. Br J Anaesth. 2021 Nov;127(5):704-712. doi: 10.1016/j.bja.2021.07.021.Epub 2021 Aug 28. PMID: 34465469; PMCID: PMC8579421.

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49.   Liu H,Jian M, Wang C, Nie L, Liang F, Liu K, Zhang K, Qiao H, Han R. Effect ofSugammadex During Transcranial Electrical Motor Evoked Potentials Monitoring inSpinal Surgery: A Randomized Controlled Trial. J Neurosurg Anesthesiol. 2021Nov 25. doi: 10.1097/ANA.0000000000000820. Epub ahead of print. PMID: 34839318.

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