★ 近五年，本课题组多人获国家奖学金、优秀毕业生称号

★ 与国外联合培养博士研究生；学生多次国际学术交流大会发言和访问学习（美国、加拿大、德国、西班牙、澳大利亚、日本等）

★ 培养学生在读期间多次获奖：全国统计建模大赛、“汇丰杯”中国高校 SAS 数据分析等大赛上获奖；全国卫生统计大会优秀论文一等奖等

1.    主持国家自然科学基金面上项目：“基于多模态大数据构建糖尿病视网膜病变风险预测模型的方法学研究（82373683）”，49万，2024-2027

2.    主持首都卫生发展科研专项重点攻关项目：“基于大数据建模评价连续无创测血糖 - 防控糖尿病新技术（首发 2024-1G-4261）”，100万，2024-2025

3.    主持北京市医药卫生科技促进中心研究课题：“北京市基本药物使用情况评估（TJZB-2024-142）”,29.836万，2024-2025

4.    主持国家自然科学基金面上项目：“基于CT影像特征和基因标志物构建恶性肺小结节精准诊断模型的方法学研究（82173617）”，55万，2022-2025

5.    主持北京市医药卫生科技促进中心研究课题：“医药卫生领域科技创新热点及前沿（KCZX-KT-002）”，23.61万，2023-2024

6.    主持国家卫健委项目：基于健康体检人群构建我国不同人群的主要慢病危险因素识别与风险评估预测模型（2022KJ000749），4.9万，2022-2023

7.    主持国家自然科学基金面上项目：“基于复轮廓波变换提取多模态影像纹理及相关因素构建深度信念网络肺癌早期诊断模型（81773542）”，55万，2018-2021

8.    主持国家科技部“十三五”重点研发项目课题：“消化道恶性肿瘤高危人群识别及癌变风险预测分级模型研究（2016YFC1302804）”，120万元，2017-2021

9.    主持北京市教委B类重点项目：“基于肺部多模态图像辅助诊断肺癌的方法及智能化系统研究（KZ201810025031）”，79.6万元，2018-2020

10.  主持国家自然科学基金重点项目：“2型糖尿病导致视网膜病变的风险评估和预测方法学研究（81530087）”，327.6万，2016-2020

11.  主持北京市教委委托项目：“北京市中小学生近视诱因分析和干预措施（PXM2019_014226_000006）”，52.9万元，2019-2019

12.  主持北京市自然基金专题重点项目：“面向糖尿病管理的移动医疗关键技术研究（Z160002）”，100万元，2016-2019

一、重要学术论文

1. Jinqi Wang#, Yixing Tian#, Xiaoyu Zhao, Chen Sheng, Haibin Li, Xia Li, Haiping Zhang, Lixin Tao, Zhiyuan Wu, Xiuhua Guo, Ding Ding. Life Course Adversity, Premature Mortality, and Life Expectancy: Role of Life’s Essential 8. European Journal of Preventive Cardiology, 2025, zwaf521. doi: 10.1093/eurjpc/zwaf521. (IF= 7.6, 中科院一区, JCR 1区)

2. Jinqi Wang, Danyang Jiao, Xiaoyu Zhao, Yixing Tian, Haibin Li, Xia Li, Chen Sheng, Lixin Tao, Hui Chen, Zhiyuan Wu, Xiuhua Guo*. Childhood loneliness and cognitive decline and dementia risk in middle-aged and older adults. JAMA Network Open, 2025, 8(9): e2531493. doi:10.1001/jamanetworkopen.2025.31493. (IF= 10.7, 中科院一区, JCR 1区)

3. Jinqi Wang#, Xiaoyu Zhao#, Yanchen Zhao, Rui Jin, Yunfei Li, Jiahe Wang, Yueruijing Liu, Zhiyuan Wu, Xiuhua Guo*, Lixin Tao*. Discordance of Small Dense LDL Cholesterol Beyond LDL Cholesterol or Non-HDL Cholesterol and Carotid Plaque. JACC: Asia, 2025, 5(8): 1012-1028. doi:10.1016/j.jacasi.2025.04.015.

4. Jinqi Wang#, Xiaoyu Zhao#, Yanchen Zhao, Zhiyuan Wu, Xia Li, Jing Wei, Xiuhua Guo*, Lixin Tao*. The Associations of Joint Exposure to Various Living Environmental Factors With the Risk of Frailty and All‑cause Mortality: A Nationally Representative Cohort Study. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2025, 80(7): glaf102. doi:10.1093/gerona/glaf102. (IF= 4.8, 中科院二区, JCR 1区)

5. 12.Jinqi Wang#, Xiaoyu Zhao#, Jiahe Wang, Yueruijing Liu, Yunfei Li, Yanchen Zhao, Rui Jin, Zongkai Xu, Zhiyuan Wu, Xiuhua Guo*, Lixin Tao*. Cumulative burden of estimated glomerular filtration rate and the risk of intracranial atherosclerosis: a prospective cohort study. Postgraduate Medicine, 2025. Accepted. (IF= 3.1, 中科院三区, JCR 1区)

6. Hammad Zaheer#, Shiyun Lv#, Zhiwei Li, Zhiyuan Wu, Feng Lu, Moning Guo, Lixin Tao, Bo Gao, Xiaonan Wang, Xia Li, Wei Wang, Xiangtong Liu, Xiuhua Guo*. Association between short-term exposure to ambient PM2.5 and its components with hospital admissions for patients with coronary heart disease and comorbid diabetes mellitus in Beijing, China. Environmental Research, 2025, 269: 120729. (IF= 7.7, 中科院二区, JCR 1区)

7. Yixing Tian#, Jinqi Wang#, Tianyu Zhu, Xia Li, Haiping Zhang, Xiaoyu Zhao, Xinghua Yang, Yanxia Luo, Lixin Tao, Zhiyuan Wu, Xiuhua Guo. Biological Age Acceleration Associated with the Progression Trajectory of Cardio-Renal–Metabolic Multimorbidity: A Prospective Cohort Study. Nutrients, 2025, 17(11): 1783. doi: 10.3390/nu17111783. 1. (IF= 5.0, 中科院二区, JCR 1区)

8. Tianyu Zhu, Yixing Tian, Jinqi Wang, Zhiyuan Wu, Wenhan Xie, Haotian Liu, Xia Li, Lixin Tao, Xiuhua Guo. The Relationship between Visceral Fat Accumulation and Risk of Cardiometabolic Multimorbidity: The Roles of Accelerated Biological Aging. Nutrients, 2025, 17(8): 1397. doi: 10.3390/nu17081397. (IF= 5.0, 中科院二区, JCR 1区)

9. Xiaoyu Zhao#, Jinqi Wang#, Zhiyuan Wu, Haibin Li, Zhiwei Li, Yueruijing Liu, Xia Li, Xiuhua Guo*, Lixin Tao*. Association of residential green space with risk of sarcopenia and the role of air pollution: evidence from UK Biobank. Environmental Pollution, 2025, 14: 125857. (IF= 8.1, 中科院二区, JCR 1区)

10. Yang R, Li W, Yu S, Wu Z, Zhang H, Liu X, Tao L, Li X, Huang J, Guo X. Enhanced NSCLC subtyping and staging through attention-augmented multi-task deep learning: A novel diagnostic tool. International Journal of Medical Informatics, 2025, 193: 105694. (IF= 3.7, 中科院三区, JCR 2区)

11. Wu Z, Jiang Y, Guo Z, Li P, Zheng Y, Wang Y, Zhang H, Balmer L, Li X, Tao L, Zhang Q, Gao B, Guo X. Remnant cholesterol traits and risk of stroke: A multivariable Mendelian randomization study. PNAS Nexus. 2024 Feb 1;3(2):pgae033. (IF= 2.2，JCR 1区)

12. Wu Z, Zhang H, Jiang Y, Li Z, Wang Y, Tian Y, Guo Z, Zheng Y, Li X, Tao L, Guo X. Association of Abnormal Lung Function and Its Subtypes With Arterial Stiffness: A Longitudinal Cohort Study. J Am Heart Assoc. 2024 Jan 2;13(1):e029929. (IF= 5, 中科院二区, JCR 1区)

13. Yang R, Zhang Y, Li W, Li Q, Liu X, Zhang F, Liang Z, Huang J, Li X, Tao L, Guo X. Development and external validation of a multimodal integrated feature neural network (MIFNN) for the diagnosis of malignancy in small pulmonary nodules (≤10 mm). Biomed Phys Eng Express. 2024 May 8;10(4). (IF= 1.3, JCR 3区)

14. Yang R, Li W, Yu S, Wu Z, Zhang H, Liu X, Tao L, Li X, Huang J, Guo X. Deep Learning Model for Pathological Grading and Prognostic Assessment of Lung Cancer Using CT Imaging: A Study on NLST and External Validation Cohorts. Acad Radiol. 2024:S1076-6332(24)00592. (IF= 3.8, 中科院三区, JCR 1区)

15. Shiyun Lv, Zhiwei Li, Haibin Li, Mengmeng Liu, Zhiyuan Wu, Siqi Yu, Binqiang Wu, Bo Gao, Lixin Tao, Yanxia Luo, Xia Li, Xiuhua Guo*, Xiangtong Liu*, Long-term effects of PM2.5 components on hypertension: A national analysis in China, Environmental Research, 2023, 222:115323. (IF= 8.3, 中科院二区, JCR 1区)

16. Zhiwei Li, Feng Lu, Mengmeng Liu, Moning Guo, Lixin Tao, Tianqi Wang, Mengyang Liu, Xiuhua Guo*, Xiangtong Liu*, Short-Term Effects of Carbon Monoxide on Morbidity of Chronic Obstructive Pulmonary Disease With Comorbidities in Beijing. Geohealth. 2023, 7(3):e2022GH000734.(IF= 4.8, 中科院二区, JCR 2区)

17. Zhiwei L, Shiyun Lv, Feng Lu, Moning Guo, Zhiyuan Wu, Yue Liu, Weiming Li, Mengmeng Liu, Siqi Yu, Yanshuang Jiang, Bo Gao, Xiaonan Wang, Xia Li, Wei Wang, Xiangtong Liu*, Xiuhua Guo*, Causal Associations of Air Pollution With Cardiovascular Disease and Respiratory Diseases Among Elder Diabetic Patients. Geohealth. 2023, 7(6):e2022GH000730. (IF= 4.8, 中科院二区, JCR 2区)

18. Huiying Pan#, Zhiyuan Wu#, Haiping Zhang, Jie Zhang, Yue Liu, Zhiwei Li, Wei Feng, Guiqi Wang, Yong Liu, Deli Zhao, Zhiyi Zhang, Yuqin Liu, Zhe Zhang, Xiangtong Liu, Lixin Tao, Yanxia Luo, Xiaonan Wang, Xinghua Yang, Feng Zhang, Xia Li, Xiuhua Guo*, Identification and validation of IgG N-glycosylation biomarkers of esophageal carcinoma. Frontiers in Immunology. 2023, 14:981861. (IF= 7.3, 中科院二区, JCR 1区)

19. Shiyun Lv, Yadi Shi, Yongxi Xue, Yaoyu Hu, Meiling Hu, Shuting Li, Wenhan Xie, Yuan Li, Yixin Ouyang, Zhiwei Li, Mengmeng Liu, Jing Wei, Xiuhua Guo*, Xiangtong Liu*, Long-term effects of particulate matter on incident cardiovascular diseases in middle-aged and elder adults: The CHARLS cohort study. Ecotoxicology and Environmental Safety. 2023, 262:115181. (IF= 6.9, 中科院二区, JCR 1区)

20. Weiming Li, Siqi Yu , Runhuang Yang, Yixing Tian, Tianyu Zhu, Haotian Liu, Danyang Jiao Feng Zhang, Xiangtong Liu, Lixin Tao, Yan Gao, Qiang Li,Jingbo Zhang and Xiuhua Guo*, Machine Learning Model of ResNet50-Ensemble Voting for Malignant-Benign Small Pulmonary Nodule Classification on Computed Tomography Images. Cancers (Basel). 2023, 15(22):5417. (IF= 5.2, 中科院二区, JCR 2区)

21. Zhiyuan Wu#, Haiping Zhang#, Yutao Wang, Zhiwei Li, Xia Li, Lixin Tao*, Xiuhua Guo*, Temporal and Bidirectional Association Between Blood Pressure Variability and Arterial Stiffness: Cross-Lagged Cohort Study. JMIR Public Health and Surveillance. 2023, 9:e45324. (IF= 8.5, 中科院二区, JCR 1区)

22. Zhiyuan Wu#, Jinqi Wang#, Haiping Zhang, Huiying Pan, Zhiwei Li, Yue Liu, Xinlei Miao, Ze Han, Xiaoping Kang, Xia Li, Xiuhua Guo*, Lixin Tao*, Wei Wang*, Longitudinal association of remnant cholesterol with joint arteriosclerosis and atherosclerosis progression beyond LDL cholesterol. BMC Medicine. 2023, 21(1):42. (IF= 9.3, 中科院一区, JCR 1区)

23. Zhiyuan Wu#, Yue Jiang#, Pingan Li, Yutao Wang, Haiping Zhang, Zhiwei Li, Xia Li, Lixin Tao*, Bo Gao*, Xiuhua Guo*, Association of impaired sensitivity to thyroid hormones with hyperuricemia through obesity in the euthyroid population. Journal of Translational Medicine. 2023, 21(1):436. (IF= 7.4, 中科院二区, JCR 1区)

24. Zhiyuan Wu#, Yue Jiang#, Qian Zhu, Haiping Zhang, Zhiwei Li, Jinqi Wang, Huiying Pan, Zheng Guo, Yulu Zheng, Xia Li, Lixin Tao, Bo Gao*, Xiuhua Guo*, Combined Evaluation of Arterial Stiffness and Blood Pressure Promotes Risk Stratification of Peripheral Arterial Disease. JACC Asia.2023, 3(2):287-297.

25. Yanfei Zhang, Wei Feng, Zhiyuan Wu, Weiming Li, Lixin Tao, Xiangtong Liu, Feng Zhang, Yan Gao, Jian Huang, Xiuhua Guo*, Deep-Learning Model of ResNet Combined with CBAM for Malignant-Benign Pulmonary Nodules Classification on Computed Tomography Images. Medicina-Lithuania.2023, 59(6):1088. (IF= 2.6, 中科院四区, JCR 3区).

26. Zhiyuan Wu#, Zheng Guo#, Yulu Zheng#, Yutao Wang, Haiping Zhang, Huiying Pan, Zhiwei Li, Lois Balmer, Xia Li, Lixin Tao*, Xiuhua Guo*, Wei Wang*. IgG N-Glycosylation Cardiovascular Age Tracks Cardiovascular Risk Beyond Calendar Age. Engineering. 2023, 26:99-107. (IF= 12.834, 中科院一区, JCR 1区). 

27. Shiyun Lv#, Xiangtong Liu#, Zhiwei Li, Feng Lu, Moning Guo, Mengmeng Liu, Jing Wei, Zhiyuan Wu, Siqi Yu, Shihong Li, Xia Li, Wenkang Gao, Lixin Tao, Wei Wang, Jinyuan Xin*, Xiuhua Guo*. Causal effect of PM1 on morbidity of cause-specific respiratory diseases based on a negative control exposure, Environmental Research, 2023, 216(Pt 4):114746 (IF= 8.3, 中科院二区, JCR 1区)

28. Wu Z#, Yu S#, Zhang H, Guo Z, Zheng Y, Xu Z, Li Z, Liu X, Li X, Chen S, Zhang J, Tao L*, Guo X*. Combined evaluation of arterial stiffness, glycemic control and hypertension for macrovascular complications in type 2 diabetes. Cardiovasc Diabetol. 2022, 21(1):262. (IF= 8.949, 中科院一区, JCR 1区)

29. Wu Z#, Zhang H#, Li Z, Li H, Miao X, Pan H, Wang J, Liu X, Kang X, Li X, Tao L*, Guo X*. Mutual effect of homocysteine and uric acid on arterial stiffness and cardiovascular risk in the context of predictive, preventive, and personalized medicine. 2022 Sep. The EPMA Journal. 2022;13(4):581-595. (IF= 8.836, 中科院一区, JCR 1区)

30. Wu Z#, Yu S#, Zhu Q, Li Z, Zhang H, Kang X, Xu Z, Miao X, Liu X, Li X, Zhang J, Wang W, Tao L*, Guo X*. Association of baseline and cumulative remnant cholesterol with incidence of diabetic nephropathy: A longitudinal cohort study. Diabetes Res Clin Pract. 2022, 191:110079. (IF= 8.180, 中科院三区, JCR 1区)

31. Qiang Xu #, Zhiwei Li#, Xiaoai Zhang #, Jinlong Wang, Haiyang Zhang, Liping Wang, Xiuhua Guo*, Liqun Fang*, Wei Liu*. The imported infections among    foreign travelers in China: an observational study. Globalization and Health, 2022, 18(1): 1-10 (IF= 10.401, 中科院一区, JCR 1区)

32. Li Z, Liu M, Wu Z, Liu Y, Li W, Liu M, Lv S, Yu S, Jiang Y, Gao B, Wang X, Li X, Wang W, Lin H, Guo X, Liu X. Association between ambient air pollution and hospital admissions, length of hospital stay and hospital cost for patients with cardiovascular diseases and comorbid diabetes mellitus: Base on 1,969,755 cases in Beijing, China, 2014-2019. Environ Int. 2022: 165:107301. (IF = 13.352, 中科院一区, JCR 1区).

33. Wu Z#, Jiang Y#, Zhou D, Chen S, Zhao Y, Zhang H, Liu Y, Li X, Wang W, Zhang J, Kang X, Tao L*, Gao B*, Guo X*. Sex-specific Association of Subclinical Hypothyroidism With Incident Metabolic Syndrome: A Population-based Cohort Study. J Clin Endocrinol Metab. 2022,17;107(6):e2365-e2372. (IF = 6.134, 中科院二区, JCR 1区)

34. Wu ZY#, Yu SQ#, Kang XP, Liu Y, Xu ZK, Li ZW, Wang JQ, Miao XL, Liu XT, Li xia, Zhang JB, Wang W, Tao LX*, Guo X*. Association of visceral adiposity index with incident nephropathy and retinopathy: a cohort study in the diabetic population. Cardiovascular Diabetology, 2022: 21(1):32. (IF = 8.949, 中科院一区, JCR 1区).

35. Mengyang Liu#, Zhiwei Li#, Mengmeng Liu, Yingxuan Zhu, Yue Liu, Mandela William Nzoyoum Kuetche3, Jianpeng Wang4, Xiaonan Wang, Xiangtong Liu, Xia Li5, Wei Wang, Xiuhua Guo*, Lixin Tao*. Association between temperature and COVID-19 transmission in 153 countries. Environmental Science and Pollution Research, 2022, 29(11):16017-16027. (IF= 5.190, 中科院二区, JCR 2区)

36. Mengmeng Liu, Zhiwei Li, Feng Lu, Moning Guo, Lixin Tao , Mengyang Liu , Yue Liu , Aklilu Deginet , Yaoyu Hu , Yutong Li , Mengqiu Wu , Yanxia Luo, Xiaonan Wang, Xinghua Yang, Bo Gao, Xiuhua Guo* , Xiangtong Liu*. Acute effect of particulate matter pollution on hospital admissions for cause-specific respiratory diseases among patients with and without type 2 diabetes in Beijing, China, from 2014 to 2020. Ecotoxicology and Environmental Safety, 2021, 226: 112794.（IF= 7.129, 中科院一区, JCR 1区）

37. Xiangtong Liu, Zhiwei Li, Moning Guo, Jie Zhang, Lixin Tao, Xiaolin Xu, Aklilu Deginet, Feng Lu, Yanxia Luo, Mengmeng Liu, Mengyang Liu, Yue Sun, Haibin Li, Xiuhua Guo*. Acute effect of particulate matter pollution on hospital admissions for stroke among patients with type 2 diabetes in Beijing, China, from 2014 to 2018. Ecotoxicology and Environmental Safety, 2021, 217: 112201.（IF=7.129, 中科院一区, JCR 1区）

38. Mengyang Liu # , Mengmeng Liu# , Zhiwei Li, Yingxuan Zhu, Yue Liu, Xiaonan Wang, Lixin Tao, Xiuhua Guo*. The spatial clustering analysis of COVID-19 and its associated factors in mainland China at the prefecture level. Science of the Total Environment. 2021,777:145992.（IF= 10.753, 中科院一区, JCR 1区）

39. Xiangtong Liu#, Zhiwei Li#, Jie Zhang, Moning Guo, Feng Lu, Xiaolin Xu, Aklilu Deginet, Mengmeng Liu, Zhaomin Dong, Yaoyu Hu, Mengyang Liu, Yutong Li, Mengqiu Wu, Yanxia Luo, Lixin Tao*, Hualiang Lin*, Xiuhua Guo*The association between ozone and ischemic stroke morbidity among patients with type 2 diabetes in Beijing, China,Sci Total Environ. 2021,818: 151733. (IF= 10.753, 中科院一区, JCR 1区)

40. Wu Z#, Zhou D#, Liu Y, Li Z, Wang J, Han Z, Miao X, Liu X, Li X, Wang W, Guo X*, Tao L*. Association of TyG index and TG/HDL-C ratio with arterial stiffness progression in a non-normotensive population. Cardiovasc Diabetol. 2021,20(1):134. (IF = 8.949, 中科院一区, JCR 1区).

41. Jiang H#, Liu M#, Zhang Y#, Yin J, Li Z, Zhu C, Li Q, Luo X, Ji T, Zhang J, Yang Y, Wang X, Luo Y, Tao L, Zhang F, Liu X, Li W*, Guo X*. Changes in Incidence and Epidemiological Characteristics of Pulmonary Tuberculosis in Mainland China, 2005-2016. JAMA Netw Open. 2021,4(4):e215302. (IF= 13.353, 中科院一区, JCR 1区)

42. Wu Zhiyuan#, Zhang Haiping#, Miao Xinlei, Li Haibin, Pan Huiying, Zhou Di, Liu Yue, Li Zhiwei, Wang Jinqi Liu X, Zheng Deqiang, Li Xia, Wang Wei, Guo Xiuhua*, Tao Lixin*. High-intensity physical activity is not associated with better cognition in the elder: evidence from the China Health and Retirement Longitudinal Study. Alzheimers Res Ther. 2021, 13(1):182.  (IF= 8.823, 中科院二区, JCR 1区)

43. Han Y, Li W, Liu M, Wu Z, Zhang F, Liu X, Tao L, Li X, Guo X. Application of an Anomaly Detection Model to Screen for Ocular Diseases Using Color Retinal Fundus Images: Design and Evaluation Study. J Med Internet Res. 2021, 23(7):e27822. (IF= 7.076, 中科院二区, JCR 1区)

44. Zhiwei Li, Xiangtong Liu, Mengyang Liu, Zhiyuan Wu, Yue Liu, Weiming Li, Mengmeng Liu, Xiaonan Wang, Bo Gao, Yanxia Luo, Xia Li, Lixin Tao, Wei Wang, Xiuhua Guo*. The Effect of the COVID-19 Vaccine on Daily Cases and Deaths Based on Global Vaccine Data. Vaccines. 2021, 9(11), 1328. （IF= 4.961, 中科院三区, JCR 2区）

45. Wu Z#, Wang J#, Li Z, Han Z, Miao X, Liu X, Li X, Wang W, Guo X*, Tao L*. Triglyceride glucose index and carotid atherosclerosis incidence in the Chinese population: A prospective cohort study. Nutr Metab Cardiovasc Dis. 2021,31(7):2042-2050. (IF= 4.666, 中科院三区, JCR 2区)

46. Wu Z, Pan H, Liu D, Zhou D, Tao L, Zhang J, Wang X, Li X, Wang Y, Wang W, Guo X. Variation of IgG N-linked glycosylation profile in diabetic retinopathy. J Diabetes. 2021,13(8):672-680. (IF= 4.530, 中科院二区, JCR 2区)

47. Wu Z#, Li L#, Jin R, Liang L, Hu Z, Tao L, Han Y, Feng W, Zhou D, Li W, Lu Q, Liu W, Fang L, Huang J, Gu Y, Li H*, Guo X*. Texture feature-based machine learning classifier could assist in the diagnosis of COVID-19. Eur J Radiol. 2021,137:109602. (IF= 4.531, 中科院二区, JCR 2区)

48. Wu Z, Pan H, Liu D, Zhou D, Tao L, Zhang J, Wang X, Wang Y, Wang W, Guo X. Association of IgG Glycosylation and Esophageal Precancerosis Beyond Inflammation. Cancer Prev Res (Phila). 2021,14(3):347-354. (IF= 3.296, 中科院三区, JCR 3区)

49. Yong Han, Yuan Ma, Zhiyuan Wu, Feng Zhang, Deqiang Zheng, Xiangtong Liu, Zhigang Liang, Jian Huang, Xia Li, Zhi Yang, Xiuhua Guo. Histologic subtype classification of non-small cell lung cancer using PET/CT images. European Journal of Nuclear Medicine and Molecular Imaging.2021,48(2):350-360. (IF= 10.057, 中科院一区, JCR 1区).

50. Amsalu E, Liu M, Li Q, Wang X, Tao L, Liu X, Luo Y, Yang X, Zhang Y, Li W, Li X, Wang W, Guo X*. Spatial-temporal analysis of cause-specific cardiovascular hospital admission in Beijing, China. Int J Environ Health Res, 2021, 31(6): 595-606. (IF= 4.477, 中科院四区, JCR 2区)

51. NCD Risk Factor Collaboration (NCD-RisC)*: Leandra Abarca-Gómez, Ziad A Abdeen, Shynar Abdrakhmanova, Xiu-Hua Guo, Monika Zuziak, et al. Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants. Lancet. 2020,396(10261): 1511-1524. (IF= 202.731)

52. Liu Xiangtong; Li Zhiwei; Zhang Jingbo; Chen Shuo; Tao Lixin; Luo Yanxia; Xu Xiaolin; Fine Jason Peter; Li Xia; Guo Xiuhua. A Novel Risk Score for Type 2 Diabetes Containing Sleep Duration: A 7-Year Prospective Cohort Study among Chinese Participants. Journal of diabetes research, 2020: 2969105. (IF= 4.061)

53. Wu Y#, Liu MY#, Wang JL#, Zhang HY, Sun Y, Yuan Y, Zhou SX, Wang YX, Wang ZB, Zhu YX, Han Y, Liu MM, Li WM, Wang LP#, Guo XH#, Fang LQ, Liu W#. Epidemiology of imported infectious diseases, China, 2014-18. Journal of Travel Medicine. 2020.taaa211. (IF= 39.194)

54. Li H, Li C*, Wang A, Qi Y, Feng W, Hou C, Tao L, Liu X, Li X, Wang W, Zheng D*, Guo X*. Associations between social and intellectual activities with cognitive trajectories in Chinese middle-aged and older adults: a nationally representative cohort study. Alzheimers Res Ther. 2020,12(1):115. (IF= 8.823)

55. Aklilu D, Wang T, Amsalu E, Feng W, Li Z, Li X, Tao L, Luo Y, Guo M, Liu X*, Guo X*. Short-term effects of extreme temperatures on cause specific cardiovascular admissions in Beijing, China. Environmental Research. 2020,186:109455. (IF= 8.431)

56. Li H, Qian F, Hou C, Li X, Gao Q, Luo Y, Tao L, Yang X, Wang W, Zheng D, Guo X. Longitudinal Changes in Depressive Symptoms and Risks of Cardiovascular Disease and All-Cause Mortality: A Nationwide Population-Based Cohort Study. J Gerontol A Biol Sci Med Sci. 2020,75(11): 2200-2206. (IF= 6.591)

57. Feng W, Halm-Lutterodt NV, Tang H, Mecum A, Mesregah MK, Ma Y, Li H, Zhang F, Wu Z, Yao E, Guo X. Automated MRI-Based Deep Learning Model for Detection of Alzheimer's Disease Process. Int J Neural Syst. 2020,30(6):2050032. (IF= 6.325)

58.  Li H, Wang A, Gao Q, Wang X, Luo Y, Yang X, Li X, Wang W, Zheng D*, Guo X*. Prevalence of somatic-mental multimorbidity and its prospective association with disability among older adults in China. Aging (Albany NY). 2020,12(8):7218-7231. (IF= 5.955)

59. N Gao#, S Tian#, X Li, J Huang, J Wang, S Chen, Y Ma, X Liu, XH Guo. Three-dimensional texture feature analysis of pulmonary nodules in CT images: Lung cancer predictive models based on support vector machine classifier. Journal of Digital Imaging. 2020, 33(2): 414-422. (IF= 4.903)

60. Wu Z, Li H, Liu D, Tao L, Zhang J, Liang B, Liu X, Wang X, Li X, Wang Y, Wang W, Guo X. IgG Glycosylation Profile and the Glycan Score Are Associated with Type 2 Diabetes in Independent Chinese Populations: A Case-Control Study. J Diabetes Res. 2020,2020:5041346. (IF= 4.061)

61. Ruling Yang#, Mengyang Liu#, Hui Jiang,Yingjie Zhang, Jinfeng Yin,  Qihuan Li, Qing L, Yue Liu，Xiaonan Wang, Hongmei Xu, Yang Yang, Weimin Li*, Xiuhua Guo*. The epidemiology of pulmonary tuberculosis in children in Mainland China, 2009-2015. Archives of Disease in Childhood. 2020,105(4):319-325. (IF= 4.920)

62. D Zheng, H Li, F Ai, F Sun, M Singh, X Cao, J Jiang, Y He, Z Tang*, XH Guo*. Association between the triglyceride to high-density lipoprotein cholesterol ratio and the risk of type 2 diabetes mellitus among Chinese elderly: the Beijing Longitudinal Study of Aging. BMJ Open Diabetes Research & Care. 2020,8 (1):08-11. (IF= 4.179)

63. X Liu, J Zhang, J Wu, X Xu , L Tao Y, Sun, S Chen, Y Han, Y Luo, X Yang, XH Guo.The Impact of BMI categories on metabolic abnormality development in chinese adults who are metabolically healthy: A 7-Year prospective study. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 2020, 13: 819-834. (IF= 3.249)

64. J Zhou, W Gu, S Li, L Wu, Y Gao, X Guo. Predictors affecting myopic regression in - 6.0D to - 10.0D myopia after laser-assisted subepithelial keratomileusis and laser in situ keratomileusis flap creation with femtosecond laser-assisted or mechanical microkeratome-assisted. International Ophthalmology. 2020,40(1): 213-225. (IF= 2.029)

65. Yue Liu#, Lixin Tao#, Jie Zhang, Jia Liu, Haibin Li, Xiangtong Liu, Yanxia Luo, Jingbo Zhang, Wei Wang, Xiuhua Guo*. Impact of Commuting Mode on Obesity Among a Working Population in Beijing, China: Adjusting for Air Pollution. Diabetes Metab Syndr Obes. 2020 ,13:3959-3968.

二、主编或副主编的著作/译著

1.  《 医学统计学与SPSS软件实现方法（第三版）》 主编 科学出版社 2023

2.  《健康医疗大数据建模与应用》 主编 人民卫生出版社 2022.

3.  《中华生物医学统计大辞典.现场调查统计分册》 主编 中国统计出版社 2020

4.  《医学统计学》 主编 化学工业出版社 2019

5.  《Medical Statistics》（第一版）主编 郑州大学出版社 2019

三、重要奖项

1.    基于肺部图像精细化纹理特征构建早期肺癌诊断模型创新方法及应用平台的系列研究 首都医科大学科学技术进步奖自然科学二等奖 第一完成人 2024年

2.   糖尿病及相关合并/并发症的病因影响效应与预测模型研究 首都医科大学自然科学 一等奖 第一完成人 2023年

3.   环境和抑郁状况对心血管病发病、入院及死亡影响效应的预测模型研究 首都医科大学自然科学 二等奖 第一完成人 2022年

4.  “医学统计学”入选国家高等教育智慧教育平台 课程负责人 2021年

5.   近视眼的影响因素、干预模式与评价系列研究 首都医科大学科学技术进步奖自然科学二等奖 第一完成人 2021

6.  “医学科研中的统计学方法”获批全国医药研究生精品建设课程 课程负责人 2019年

四、发明专利

1. 一种基于深度学习的图像多任务特征提取及分类系统，202410560326.3，中国发明专利. 第一完成人，2025年2月20日（郭秀花，杨润煌，李伟铭，吕世云，于思琪，张海平，王金麒，谢文涵）

2. “一类与食管癌发生发展的相关的生物标志物（Biomarkers Retated to the Occurrence and Development of Esophageal Cancer，2021/09153）”，国际（南非）发明专利. 第一完成人，2021年（郭秀花，潘荟颖，武志远，张海平，冯巍，张杰，陶丽新，王肖楠，刘相佟）

3. “基于多因素的胃癌高危人群癌变风险评估与分级模型（Multi-foctor-based  Cancer Risk Assessment and Grading Model for High-risk Population of  Gastric Cancer，2021/07262）”，国际（南非）发明专利. 第一完成人，2021年（郭秀花，冯巍，潘荟颖，武志远，张海平，张杰，陶丽新，王肖楠，刘相佟）

4.  “基于多因素的食管癌高危人群癌变风险评估与分级模型（Multi-foctor-based  Cancer Risk Assessment and Grading Model for High-risk Population of Esophageal Cancer，2021/07309）”，国际（南非）发明专利. 第一完成人，2021年（郭秀花，张海平，潘荟颖，武志远，张海平，冯巍，张杰，陶丽新，王肖楠，刘相佟）

5. “一种基于深度学习的糖尿病视网膜病变等级分类模型（A classification method of diabetic retinopathy grade based on deep learning，2020103938）”，澳大利亚发明专利. 第一完成人，2021年（郭秀花，韩勇，田思佳，马圆，陶丽新，刘相佟）

6. “一种基于肺部CT图像特征和基因标志物构建肺小结节性质的精准筛查方法（Identification Method of Pulmonary Nodules Based on Lung CT Image Features and Genetic Markers，2021102981）”，澳大利亚发明专利. 第一完成人，2021年（郭秀花，李伟铭，韩勇，陶丽新，武志远，张彦飞）

7. “一种基于眼底图像的糖尿病肾病深度学习分类诊断方法（Diabetic Nephropathy Recognition System Based on Fundus Image，2021104374）”，澳大利亚发明专利. 第一完成人，2021年（郭秀花，李伟铭，韩勇，陶丽新，刘相佟，冯巍，武志远，张彦飞）