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主持完成国家和省部级各类课题20余项。主要研究领域：药物代谢与药动学、基于低氧和组学的分子代谢。发表学术论文150余篇，其中国外SCI论文50余篇。获省院级科技进步一、二和三等奖7项。获国家发明专利授权8项。研制开发上市抗菌消炎新兽药“消炎醌”、抗血孢子虫药“焦虫净”和强力复合碘消毒剂。主编副主编出版专著（译著）教材10余部。培养博士后、博/硕士研究生40多名。
1、国家自然科学基金项目：基于多组学和酵母低氧模型的神经酰胺关键代谢途径、调控网路及抗低氧作用的确证，2021.1-2024.12.
2、国家自然科学基金项目：基于组学和斑马鱼模型的缺氧关键代谢途径、调控网路及相关活性物质的分析表征和确证，2018.1-2021.12.
3、国家自然科学基金项目：缺氧对抗缺氧中药红景天活性成分代谢、转运与药代动力学及作用的影响及其分子机制，2016.1-2019.12.
1． Zhengchao Xia, Xuelin Zhou,Jingyi Li, Lei Li, Yi Ma, Yi Wu, Zhong Huang, Xiaorong Li, Pingxiang Xu, Ming Xue*. Multiple-omics techniquesreveal the role of glycerophospholipid metabolic pathway in the response ofSaccharomyces cerevisiae against hypoxic stress. Frontiers in Microbiology,2019, 10:1398.
2. Yi Ma, YiWu, ZhengchaoXia, Jingyi Li, XiaorongLi,Pingxiang Xu, XuelinZhou*, Ming Xue*.Anti-Hypoxic molecularmechanisms of Rhodiola crenulata extract in zebrafish asrevealed by metabonomics. Frontiers in Pharmacology, 2019,10:1356.
3. Pingxiang Xu, Ying Liu, Liyun Wang, Yi Wu, Xuelin Zhou, Junhai Xiao, Jianquan Zheng, Ming Xue*. Phencynonate S-isomer as aeutomer is a novel central anticholinergic drug for anti-motion sickness. Scientific Reports, 2019, 9:2000.
4. Shousi Lu, Shanshan Guo, Pingxiang Xu,Xiaorong, Li, Yuming Zhao, Wei Gu*, MingXue*. Hydrothermal synthesis of nitrogen-doped carbon dots with real-timelive-cell imaging and blood–brain barrier penetration capabilities.International Journal of Nanomedicine, 2016, 11, 6325–6335.
5. Huanli Xu, Qunying Chen, Hong Wang, Pingxiang Xu,Ru Yuan, Xiaorong Li, Lu Bai, Ming Xue*.Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo bytargeting DNA topoisomerase I and topoisomerase II. Journal of Experimental& Clinical Cancer Research, 2016, 35, 178-187.
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