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教育经历
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2020~至今 .首都医科大学附属北京康复医院 科研管理部 副研究员、副教授
2015~2019 首都医科大学附属北京潞河医院 中美神经研究所 助理研究员
学术兼职
中国老年医学会脑血管病分会 常务委员
中国康复医学会青年工作委员会 常务委员
中国康复医学会科技管理与评估委员会 秘书长
Frontiers in Cellular Neuroscience (SCI, IF:6.147) 客座主编
Frontiers in Neurology (SCI, IF:4.086) 客座主编
Chinese Neurosurgery Journal 青年编委
Brain Network and Modulation 编委
中国电子学会生命电子分会 理事
1. 国家自然科学基金面上项目,负载Treg多功能凝胶微球脑内注射增强神经可塑性促进脑卒中康复的作用与机制研究,2023-2026,基金号:82272616,课题负责人,资助金额:52万
2.国家自然科学基金面上项目,褪黑素对缺血性卒中白质损伤的保护作用及机制研究,2017-2020,基金号:81671161,课题负责人,资助金额:60万
3. 科技部重点研发计划“重大慢性非传染性疾病防控研究”,远隔缺血适应对慢性脑缺血免疫调控和血液标志物研究,2017-2020,基金号:2017YFC1308403,子课题负责人,资助金额:20万
4. 北京市自然科学基金面上项目,原位注射负载Tregs的多功能凝胶微球对脑卒中免疫康复治疗作用及机制研究,2022-2024,基金号:7222102,课题负责人,资助金额:20万元
5. 北京市自然科学基金预探索项目,调节性T细胞治疗对卒中tPA静脉溶栓后脑出血及长期神经功能的影响,2016-2017,基金号:7163219,课题负责人,资助金额:6万元
6. 北京市博士后基金,2014-2015,基金号:2014ZZ,课题负责人,资助金额:3万
发表SCI论文44篇,其中第一/通讯作者23篇,SCI 他引逾1200次,H指数(H-index)18,IF>5分12篇,单篇最高IF 29.190,单篇最高他引83次;授权国家专利5项;出版译著1部。
10篇代表性论文:
1. Zongjian Liu#, Lin Ye#, Jianing Xi, Jin Wang, Zengguo Feng. Cyclodextrin polymers: Structure, synthesis, and use as drug carriers. Prog Poly Sci. 2021,118:101408-101431(IF: 31.281)
2.XiaoyuMa, Fuhai Gao, Wei Su, Yuanyuan Ran*, Tuerhong Bilalijiang, YeraselTuolhen, Guiqin Tian, Lin Ye*, Zengguo Feng, Jianing Xi* and ZongjianLiu*. Multifunctional injectable hydrogel promotes functional recoveryafter stroke by modulating microglial polarization, angiogenesis andneuroplasticity Chemical EngineeringJournal. 2023. SCI (IF=16.744)
3.Zongjian Liu; Shulei Zhang; Yuanyuan Ran; HuiminGeng; Fuhai Gao; Guiqin Tian; Zengguo Feng; JianingXi; LIN YE; Wei Su, Nanoarchitectonics of tannic acid based injectablehydrogel regulate the microglial phenotype toenhance neuroplasticity for poststrokerehabilitation. Biomaterials Research. (IF=11.3)
4.Qiao C, Liu Z, Qie S. The Implications of Microglial Regulation in Neuroplasticity-Dependent Stroke Recovery. Biomolecules. 2023 Mar 21;13(3):571. doi: 10.3390/biom13030571. (IF=5.5)
5.Xuechai Chen, Jianan Wang, Muhammad Tahir, Fangfang Zhang, Yuanyuan Ran, Zongjian Liu*, Juan Wang*. Current insights into the implications of m6A RNA methylation and autophagy interaction in human diseases. Cell & Bioscience. 2021,11(1):147. doi: 10.1186/s13578-021-00661-x. (IF: 9.584)
6. Yuanyuan Ran#, Wei Su#, Fuhai Gao, Zitong Ding, Shuiqing Yang, Lin Ye, Xuechai Chen, Guiqin Tian, Jianing Xi*, Zongjian Liu*. Curcumin Ameliorates White Matter Injury after Ischemic Stroke by Inhibiting Microglia/Macrophage Pyroptosis through NF-κB Suppression and NLRP3 Inflammasome Inhibition.Oxidative Medicine and Cellular Longevity. 2021 Sep 30;2021:1552127. (IF: 7.31)
7. Fang Yu, Tingting Huang, Yuanyuan Ran, Da Li, Lin Ye, Guiqin Tian, Jianing Xi* , Zongjian Liu*. New Insights Into the Roles of Microglial Regulation in Brain Plasticity-Dependent Stroke Recovery. Frontiers in Cellular Neuroscience. 2021, 15:727899. doi: 10.3389/fncel.2021.727899 (IF: 6.147)
8. Yuanyuan Ran, Lin Ye; Zitong Ding, Fuhai Gao, Shuiqing Yang, Boyan Fang, Zongjian Liu*, Jianing Xi*. Melatonin Protects Against Ischemic Brain Injury by Modulating PI3KAKT Signaling Pathway via Suppression of PTEN Activity. American Society for Neurochemistry. 2021, 13. doi: 10.1177/17590914211022888. (IF: 5.200)
9. Zongjian Liu#, Yuanyuan Ran#, Shuyan Qie, Weijun Gong, Fuhai Gao, Zitong Ding, Jianing Xi*. Melatonin protects against ischemic stroke by modulating microglia/macrophage polarization toward anti-inflammatory phenotype through STAT3 pathway. CNS Neuroscience & Therapeutics. 2019, 25: 1353-1362. (IF: 5.243, 53 citations in website of Science)
10. Yan Zhang#, Zongjian Liu#, Wenxiu Zhang, Qichao Wu, Yanjun Zhang, Yadong Liu, Yun Guan, Xueming Chen. Melatonin improves functional recovery in female rats after acute spinal cord injury by modulating polarization of spinal microglial/macrophages. Journal of Neuroscience Research. 2019, 97(7): 733-743.(IF:4.433)
11. Yuanyuan Ran#, Zongjian Liu#,*, Shuo Huang, Jiamei Shen, Fengwu Li, Wenxiu Zhang,Chen Chen, Xiaokun Geng, Zhili Ji, Huishan Du, Xiaoming Hu*. Splenectomy Fails to Provide Long-Term Protection Against Ischemic Stroke. Aging and Disease, 2018, 9(3):467-479.(IF: 9.968, 20 citations in website of Science)
重要奖项:
中国康复医学科学技术进步 一等奖 2022
教育部科技进步 一等奖 2018
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