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主要从事先天性心脏病临床诊治，擅长先天性心脏病的微创治疗(包括婴幼儿右腋下小切口手术和全腔镜下心脏手术)和合并肺动脉高压先心病的综合治疗。主要科研方向为肺动脉高压的基础与临床研究；承担国家自然科学基金1项，北京市自然科学基金2项等课题；近年共发表先心病临床诊治和肺动脉高压SCI 论文7篇，核心期刊8篇。
1.国家自然科学基金青年项目，81600383、线粒体动力学在不可逆肺血管重构过程中的作用、2017/01-2019/12/31、17.5万元、主持
2.北京市医管局“青苗”基金，QML20170601、内皮凋亡特异性外泌体评估肺血管病变程度的研究，2018/01-2019/12/31、5万元、主持
3.北京市自然科学基金青年项目，7164252、内皮细胞凋亡标志物在评估肺血管病变程度中的作用、2016/01-2017/12、8万元、主持
4.北京安贞医院院长基金，2015401、内皮细胞凋亡标志物在评价合并重度肺动脉高压先心病手术适应症中的作用、2015/12-2017/11、3万元、主持
1. 北京市自然科学基金面上项目，7222044、线粒体Survivin在启动肺动脉内皮细胞凋亡抵抗中作用、2022/1-2024/12、20万元、主持
1. ZhangH, Chen L, Li J, Sun J, Zhao Q, Wang S, Li G. STAT3 phosphorylation at Tyr705affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fissionduring the development of apoptotic-resistance in pulmonary arterialendothelial cells. Genes Genomics. 2024 Jul;46(7):751-762.
2. LiG, Zhang H , Yang Y , et al. Pseudoaneurysm afterTetralogy ofFallot Repair Using Right Ventricular Outflow Tract Patch[J].Congenital HeartDisease, 2020, 15(5):431-439.
3. LiG,Zhang H, Fan X, Su J. Pulmonary artery banding in patients withfunctionalsingle ventricle associated with pulmonary hypertension. Clin ExpHypertens.2021 May 19;43(4):328-333. doi: 10.1080/10641963.2021.1883048IF:1.5 Q3 . Epub 2021 Feb 5.PMID: 33541150IF: 1.5 Q3 . IF1.749
4. LiG,Zhang H, Zhao L, Zhang Y, Yan D, Liu Y, Su J, Fan X. The expression ofsurvivinin irreversible pulmonary arterial hypertension rats and its valueinevaluating the reversibility of pulmonary arterial hypertension secondarytocongenital heart disease. Pulm Circ. 2019 Aug 2;9(3):2045894019859480. doi:10.1177/2045894019859480.PMID: 31428312IF: 2.2 Q2 ; PMCID:PMC6681502IF: 2.2 Q2 .
5. ZhangH,Fan X, Su J, Liu Y, Zhao L, Li G. The efficiency of systemic-to-pulmonaryshuntsin older children with hypoplastic pulmonary arteries. J Card Surg.2019Jun;34(6):463-467. doi: 10.1111/jocs.14063IF: 1.3 Q3 . Epub 2019Apr 26. PMID: 31025765IF: 1.3 Q3 .
6. LiG, Zhang H, Zhao L, Zhang Y, Yan D, Liu Y. Angiotensin-convertingenzyme 2activation ameliorates pulmonary endothelial dysfunction in rats withpulmonaryarterial hypertension through mediating phosphorylation ofendothelial nitricoxide synthase. J Am Soc Hypertens. 2017 Dec;11(12):842-852.doi:10.1016/j.jash.2017.10.009. Epub 2017 Oct 28. PMID: 29146157.
7. Li G, Su J, Fan X, Li Z, Zhang J, Zhu Y, Liu A, Xu Y, Xu Y, Liu Y.Safety and Efficacy of VentricularSeptal Defect Repair Using a Cosmetic ShorterRight Lateral Thoracotomy onInfants Weighing Less than 5kg. Heart LungCirc. 2015;24(9): 898-904.
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