1.国家自然科学基金面上项目（82271309）：IL-2Rα通过自分泌途径靶向特定星形胶质细胞亚型调节脑缺血后丘脑-皮层连接重塑的机制研究，2023.01-2026.12，在研

2.国家自然科学基金面上项目（82071314）：HDAC2转录复合体调控IL-2/sIL-2R平衡介导缺血性卒中CD4+T淋巴细胞转分化的作用及机制研究，2021.01-2024.12，在研

3.国家自然科学基金面上项目（817714125）：TOPK抑制HDAC1/2活性调控脑缺血反应性星形胶质细胞表型转化，2018.01-2021.12，结题

4.国家自然科学基金面上项目（81571280）：MiR-424靶向NFI-A调控不同年龄小鼠脑缺血后星形胶质细胞分化的神经重塑机制，2016.01-2019.12，结题

5.国家自然科学基金青年项目（81201028）：MiR-424调节细胞周期对缺血脑损伤的作用及机制，2013.01-2015.12，结题

6.北京市教委—市自然基金委联合资助项目：靶向调控中性粒细胞表型治疗缺血性脑卒中的新方法研究，2024.01-2026.12，在研

7.“扬帆3.0”医工结合培育项目（YGLX202328）：面向急性脑梗死机械取栓风险评估的中性粒细胞电学特征实时分析仪器的临床转化研究，2024.01-2026.12，在研

8.北京市科技新星计划交叉学科合作课题（Z211100002121017）：多通道脑循环芯片在缺血后免疫细胞趋化性分析中的应用研究，合作方负责人，2022.01-2023.12，在研

9.北京市教委—市自然基金委联合资助项目（KZ201810025041）：靶向调控中性粒细胞表型治疗缺血性脑卒中的新方法研究，2018.01-2020.12，结题

10.北京市科技新星计划（Z151100000315065）：PBK/TOPK调节脑缺血-再灌注小胶质细胞周期的机制研究，2015.01-2017.12，结题

11.宣武医院汇智人才工程-拔尖人才培育计划：HDAC2阻断中性粒细胞-NETs-Th17淋巴细胞环路影响缺血性卒中tPA溶栓出血转化机制研究，2021.10-2024.10，在研

2024年招收神经生物学专业博士研究生1名、硕士研究生1名

主要学术论文

1.      Haiping Zhao#, Xiaofeng Luan#, Yuqing Wang, Yifei Ye, Yan Feng, Li Xue, Yuang Li, ZhaoYang*, Huang Chengjun*, Luo Yumin*. Dynamic detection of specific membrane capacitanceand cytoplasmic resistance of neutrophils after ischemic stroke. Aging Dis. 2023, 14(4): 1035-1037. IF=9.968

2.      Yuang Li, Xue Li, Lina Zhang, Xiaofeng Luan, JiahongJiang, Lingqian Zhang, Mingxiao Li, Haiping Zhao*, Yang Zhao*, ChengjunHuang*. From teapoteffect to tap-triggered self-wetting: a 3D self-driving sieve for whole blood filtration. Microsystems & Nanoengineering. 2023, 9:30. IF=8.006

3.      Yuqian Li#, Xue Li#, Xiaokun Geng*,Haiping Zhao*. The IL-2A receptor pathway and its role in lymphocytedifferentiation and function. Cytokine Growth Factor Rev. 2022, 67:66-79. IF=17.66

4.      Fangfang Li#, Qingfeng Ma#, Lingzhi Li, Lin Zhang,Zhenhong Yang, Yuyou Huang, Ziping Han, Rongliang Wang, Zhen Tao, Yangmin Zheng,Junfen Fan, Shengpan Chen, Yumin Luo*, Haiping Zhao*. Alterationsof inflammatory cytokines in super-acute stroke patients and the potential pathogenesis.J Clin Neurosci. 2022; 99: 35-43. IF=2.116

5.      Sijia Zhang#, Lingjun Zhan#, Xue Li,Zhenhong Yang, Yumin Luo*, Haiping Zhao*. Preclinical and clinicalprogress for HDAC as a putative target for epigenetic remodeling and functionalityof immune cells. Int J Biol Sci. 2021; 17(13): 3381-3400. IF=10.750

6.      Ziping Han, Lingzhi Ling, Yuyou Huang, Haiping Zhao*,Yumin Luo*. PBK/TOPK, a therapeutic target worthy of attention. Cells. 2021Feb 11;10(2): 371. IF=7.666

7.      Jian Chen#, Haiping Zhao#, Yuyou Huang, Yuqian Li, Junfen Fan, Rongliang Wang, Ziping Han, ZhenhongYang, Longfei Wu, Di Wu, Yumin Luo*, Xunming Ji*. Dysregulation of principalcirculating miRNAs in Nonhuman Primates following ischemic stroke. Frontiersin Neuroscience. 2021 September 1; 15: 738576. IF=5.152

8.     Fangfang Zhao#, Haiping Zhao#, Junfen Fan, Rongliang Wang, Ziping Han, Zhen Tao, YangminZheng, Feng Yan, Yuyou Huang, Yumin Luo*, Yuanwu Ma*. MiR-29a knockout aggravatesneurological damage by pre-polarizing M1 microglia in experimental acute strokerat. Frontiers in Genetics. 2021 Mar 15; 12:642079. IF=4.772

9.     Fangfang Li#, Ping Liu#, Yuyou Huang, Lingzhi Li, Sijia Zhang, Zhenhong Yang, Rongliang Wang, ZhenTao, Ziping Han, Junfen Fan, Yangmin Zheng, Haiping Zhao*, YuminLuo*. The incremental prognostic value of hepatocyte growthfactor in first-ever acute ischemic stroke: an early link between growth factorand interleukins. Frontiers in Neurology. 2021 Aug 04; 12:691886. IF=4.086

10.   Haiping Zhao#, Fangfang Li#, Yuyou Huang, SijiaZhang, Lingzhi Li, Zhenhong Yang, Rongliang Wang, Zhen Tao, Ziping Han, JunfenFan, Yangmin Zheng, Qingfeng Ma*, Yumin Luo*. Prognostic significance of plasmaIL-2 and sIL-2Rα in patients with first-ever ischaemic stroke. J Neuroinflammation.2020 Aug 14;17(1):237. IF=9.587

11.   Fangfang Li#, Haiping Zhao#, Guangwen Li, Sijia Zhang, Rongliang Wang, Zhen Tao, Yangmin Zheng, ZipingHan, Ping Liu, Qingfeng Ma, Yumin Luo*. Intravenous antagomiR-494 lessensbrain-infiltrating neutrophils by increasing HDAC2-mediated repression of multipleMMPs in experimental stroke. FASEB J. 2020 May;34(5):6934-6949. IF=5.834

12.   Haiping Zhao#, Guangwen Li#, Rongliang Wang, Zhen Tao, Qingfeng Ma, Sijia Zhang,Ziping Han, Feng Yan, Fangfang Li, Ping Liu, Shubei Ma, Xunming Ji, Yumin Luo*.Silencingof microRNA-494 inhibits the neurotoxic Th1 shift via regulating HDAC2-STAT4cascade in ischaemic stroke. Br J Pharmacol.2020 Jan;177(1):128-144. IF=9.473

13.   Wenjie Zhao#, Haiping Zhao#, Mingxiao Li*, Chengjun Huang*. Microfluidic devices for neutrophilchemotaxis studies. J Transl Med. 2020 Apr 15;18(1):168. IF=8.44

14.   Haiping Zhao#, Guangwen Li#, Sijia Zhang, Fangfang Li, Rongliang Wang, Zhen Tao, QingfengMa, Ziping Han, Feng Yan, Junfen Fan, Lingzhi Li, Xunming Ji, Yumin Luo*.Inhibition of histone deacetylase 3 by MiR-494 alleviates neuronal loss andimproves neurological recovery in experimental stroke. J Cereb Blood Flow Metab. 2019 Dec;39(12):2392-2405. IF=6.96

15.   Haiping Zhao#, Guangwen Li#, Rongliang Wang, Zhen Tao, Sijia Zhang, Fangfang Li,Ziping Han, Lingzhi Li, Ping Liu, Yumin Luo*. MiR-424 prevents astrogliosis after cerebralischemia/reperfusion in elderly mice by enhancing repressive H3K27me3 via NFIA/DNMT1signaling. FEBS J. 2019 Dec; 286(24):4926-4936. IF=5.622

16.   Haiping Zhao#, Ping Liu, Changmin Xu, G Li, Li Gao, Yumin Luo*.Unique microRNAs signature of lymphocyte of yang and yin syndromes in acute ischemicstroke patients. Chin J Integr Med. 2019, 25(8):590-597. IF=2.626

17.   FangfangLi #, Haiping Zhao#, Ziping Han, Rongliang Wang, Zhen Tao, Zhibin Fan, Sijia Zhang,Guangwen Li, Zhigang Chen, Yumin Luo*.Xuesaitong may protect against ischemic stroke by modulating microglial phenotypesand inhibiting neuronal cell apoptosis via the STAT3 signaling pathway. CNS Neurol Disord Drug Targets. 2019,18(2):115-123. IF=2.824

18.  Qingfeng Ma #, Guangwen Li #, Zhen Tao, Jue Wang, Rongliang Wang, Ping Liu, Xuming Ji,Yumin Luo, HaipingZhao*. Blood miR-93a-5p as an indicatorfor diagnosis and prediction of functional recovery of acute stroke. Journal of ClinicalNeuroscience. 2019, 62:121-127. IF=2.116

19.  Ping Liu#, Ziping Han#, Qingfeng Ma, Rongliang Wang, Zhen Tao, Guangwen Li, FangfangLi, Sijia Zhang, Xunming Ji, HaipingZhao*, Yumin Luo*. Upregulation of MicroRNA-128 in the peripheral bloodof acute ischemic stroke patients is correlated with stroke severity partiallythrough inhibition of neuronal cell cycle reentry. Cell Transplantation. 2019, 28(7):839-850. IF=4.139

20.   Lingzhi Li#, Pingping Wang, Haiping Zhao*,Yumin Luo*. Noncoding RNAs and intracerebral hemorrhage. CNS Neurol Disord Drug Targets.2019, 18(3):205-211. Review. IF=2.824

著作

1. 《神经系统疾病动物模型》，主编，2017年，中国医药科技出版社

2. 《神经系统疾病中药注射液的临床应用》，副主编，2017年，中国医药科技出版社

学术奖项

1. 低氧与缺血适应防治缺血性脑卒中新技术体系的创研及推广应用，国家科学技术进步奖，二等奖，2020年。

2. 基于血流再通的缺血性卒中脑保护救治关键技术研发及应用推广，北京市科技进步奖，二等奖，2019年。

3. 活络益脑法（方）及其演变方药治疗慢性脑供血不足的神经保护作用及其机制研究，中国中西医结合学会科技进步奖，二等奖，2019年。

4. 上肢远隔缺血适应新技术的建立及其防治缺血性脑卒中的临床应用，教育部高等学校科技进步奖，一等奖，2018年。