团队合影（部分团队师生）

1.北京市自然科学基金，1S24093，基于术前CT 和术中自由3D 超声图像引导的关节镜视觉定位方法研究, 2024/10-2026/09。

2.北京市自然科学基金-丰台创新联合基金重点研究专题项目（主要参与人）, L241029, 基于定量骨CT和生物力学分析的脊柱融合术自动规划技术研究，2024/10 -2027/09。

3.首都卫生发展科研专项项目（主要参与人），首发 2024-2-2076，基于深度学习神经网络的畸形脊柱内固定手术智能规划系统研究，2024 / 01- 2026/12。

4.北京市科技计划课题AI+健康协同创新培育项目 (联合申报)，Z211100003521005，天玑机器人脊柱内固定手术人工智能规划与控制系统研究与开发，2020/12-2023/12。

5.北京市自然科学基金-海淀原始创新联合基金项目重点研究专题 (子课题)，骨科机器人辅助椎弓根螺钉内固定手术智能规划技术与临床验证，L202005，2020.12-2023.12

6.科技部高端外国专家引进计划项目，G20200123023，多模影像手术机器人系统安全成像技术研发，2020.01-2022.12。

7.国家重大科研仪器研制项目 (子课题)，61827809，临床前骨骼专用三维高分辨定量能谱CT的研制与应用，2019/01-2023/12

部分科研论文

[1] Shangqi Cui, Fan Peng, Zhi Yang, "Keypointsextraction based pose estimation in optical occlusion conditions for surgicalinstruments," Proc. SPIE 13274, Sixteenth International Conference onDigital Image Processing (ICDIP 2024), 132740P (22 October 2024);https://doi.org/10.1117/12.3037054

[2] Zehao Cai†, Zukai Yang†, Ying Wang, Ye Li , HongZhao, Hanwen Zhao, Xue Yang, Can Wang, Tengteng Meng, Xiao Tong, Hao Zheng,Zhaoyong He, Chunli Niu, Junzhi Yang, Feng Chen, Zhi Yang, Zhige Zou* andWenbin Li*, Tumor treating induced fields: a new treatment option for patientswith glioblastoma. Front. Neurol. 15:1413236. doi: 10.3389/fneur.2024.1413236,2024.

[3] Fan Peng, Yunxian Zhang, Shangqi Cui, BinbinWang, Dan Wang, Zhe Shi, Lanlin Li, Xiutong Fang*, Zhi Yang*. Segmentation ofbone surface from ultrasound using a lightweight network UBS-Net. Biomed PhysEng Express. 2024 Apr 26;10(3).

[4] Fan Peng, Shangqi Cui, Binbin Wang, Dan Wang,Zhe Shi, Lanlin Li, Zhi Yang, Calibration of Freehand Ultrasound Based on YOLOv8xKeypoints Detection Network, Proceedings of the 2023 4th InternationalSymposium on Artificial Intelligence for Medicine Science (ISAIMS 2023),Chengdu, China, October 20-22, 2023, pages 167-171, Association for ComputingMachinery, New York, NY, USA.

[5] Shangqi Cui, Fan Peng, and Zhi Yang, 2024. A New3D Human Pose Estimation Network for Knee Posture Estimation, Proceedings ofthe 2023 4th International Symposium on Artificial Intelligence for MedicineScience (ISAIMS 2023), Chengdu, China, October 20-22, 2023, pages 734–739, Associationfor Computing Machinery, New York, NY, USA.

[6] JingweiZhao; Yunxian Zhang; Shi Zhan; Qi Zhang; Dan Wang; Fan Peng; Shangqi Cui;Binbin Wang; Zhe Shi; Da He*; Bo Liu*; Zhi Yang*; Pedicle screw path planningfor multi-level vertebral fixation, Medical Physics, 2024 Mar;51(3):1547-1560.

[7]Yunxian Zhang; Wenhai Li; Jingwei Zhao; DanWang; Fan Peng; Shangqi Cui; Binbin Wang; Zhe Shi; Bo Liu*; Da He*; Zhi Yang* ;Improving pedicle screw path planning by vertebral posture estimation, Physicsin Medicine & Biology, 2023, 68(18): 10.1088/ 1361-6560/ace753.

[8] 张雨萌,张蕴显,王丹,等.超声弹性成像及生理参数在慢性肝病纤维化分级中的相关性分析[J].生物医学工程研究,2022, 41(1):1-6.

[9] Yunxian Zhang* ,Jingwei Zhao*, Dan Wang, Yumeng Zhang, Fan Peng, Shanqi Cui, Da He#, Bo Liu#,Zhi Yang#, Optimal Pedicle Screw Path Planning from Multi-directionalProjections, IEEE International Conference on Medical Imaging Physics andEngineering, Nov. 12-14, 2021, China Hefei.

[10] Dan Wang*, Yuxian Zhang,Yumeng Zhang, Fan Peng, Shanqi Cui, Da He#, Bo Liu#, Zhi Yang#, ReliableCalibration of Cone Beam CT Using Size-coding Markers, IEEE InternationalConference on Medical Imaging Physics and Engineering, Nov. 12-14, 2021, ChinaHefei.

[11] Yumeng Zhang*, Yao Zhang*#,Yunxian Zhang, Dan Wang, Fan Peng, Shangqi Cui, Zhi Yang#, Ultrasonic imagefibrosis staging based on machine learning for chronic liver disease, IEEEInternational Conference on Medical Imaging Physics and Engineering, Nov.12-14, 2021, China Hefei.

[12] Lu Zhang*, Yunhe Ding*,Xinjian Chen*, Dehui Xiang, Fei Shi, Yanyun Chen, Shenshen Yan, Xinyuan Zhang,Jie Tian, Sobha Sivaprasad, Yang Du#, Zhi Yang#, Bei Tian#, In vivofluorescence molecular imaging of the vascular endothelial growth factor inrats with early diabetic retinopathy, Biomedical Optics Express, 202112(11):7185-7198.

[13] 丁云鹤*、 严棽棽、王璐、 陈燕云、 宋婷婷、张璐、 李哲清、杨智#、田蓓#，增殖性糖尿病视网膜病变虹膜新生血管的多模态临床研究，中华眼科医学杂志，2021 11(1) 8-13.

[14] 许莉莉*、杨智、田蓓#，眼科基于图像的人工智能，中华眼科杂志， 202157(6) 465-469.

[15] Geming Wu*, Shuqian Luo,Zhi Yang#，Optimalweighted Bilateral filter with dual-range kernel for Gaussian noise removal,IET Image Processing, 2020 14(9):1840-1850.

专利授权与申请

[1] 2024214121392，王丹,杨智，双面金属材料封装药粒缺损和空泡光源探测器系统，2024.6，专利申请，实用新型；

[2] 2024221513406，王丹,杨智，一种多用途的 CT 图像质量评价模体，2024.9专利申请，实用新型；

[3] 2024114259320，王丹，杨智，史哲，一种能谱CT 图像域改善金属伪影的方法，2024.10专利申请，发明专利（进入PCT国际专利和美国专利申请）；

[4] 202410010813.2 彭璠;杨智;三维超声图像引导关节镜视觉定位系统及方法,中国,  (专利申请，于2024年05月24日进入实质审查阶段)；

[5] 2023224266410 崔尚起; 彭璠; 杨智; 骨外科手术自动化辅助摆位系统, 中国, (专利申请)；

[6] ZL 2021 1 1335937.0 张蕴显; 赵经纬; 杨智; 何达; 刘波; 王丹; 一种基于多角度投影的椎弓根螺钉最优路径规划方法,2023.7.25授权

[7] CN115568942B， 张蕴显; 赵经纬; 杨智; 何达; 刘波，多椎体联合约束的椎弓根螺钉只有轨迹规划方法及装置，中国

[8] 2022101315910，杨智，崔尚起，刘文海，基于图像的个性化腔镜自动定位导航系统，2022.02 (专利申请)；

[9] 9224216 (美国专利) AlexanderA.Zamyatin; Yongsheng Pan; Zhi Yang ; High density forward projector forspatial resolution improvement for medical imaging systems including computedtomography, 2015/12/29.

[10] 8938105 (美国专利) Zhi Yang; Michael D. Silver ; Denoising methodand system for preserving clinically significant structures in reconstructedimages using adaptively weighted anisotropic diffusion filter, 2015/1/20.

[11] 8761540 (美国专利) Zhi Yang;Alexander A. Zamyatin; Satoru Oishi; Anusha Muthu-Natarajan ; Method and systemfor estimating noise level, 2014/6/24, ,

[12] 8538114 (美国专利)Zhi Yang;Alexander A. Zamyatin; Yu Zou; Michael D. Silver ; Method and system utilizingparameter-less filter for substantially reducing streak and or noise incomputer tomography (CT) images, 2013/9/17.