主持国家级课题

1. 国自然面上项目，82371263，多模态影像学研究帕金森病早期病理传播途径，2024-01至2027-12，49万元

2. 国自然面上项目，82071423，快速眼动期睡眠行为障碍患者蓝斑影像学特征研究，2021-01至2024-12，55万元

3. 国家重点研发计划课题，2016YFC1306503，结构和功能磁共振研究，2016-10至2020-12，165.87万元

4. 国自然面上项目，81571228，帕金森病临床前期神经网络动态变化模式研究，2016-01至2019-12，68.4万元

5. 国自然面上项目，81271429，帕金森病基底节环路连接模式研究，2013-01至2016-12，70万元

6. 国自然面上项目，81071012，基于静息fMRI的帕金森病自动判别模式，2011-01至2013-12

7. 国自然面上项目，30870693，原发性肌张力障碍脑结构和功能改变，2009-01至2011-12

8. 国自然面上项目，30570530，静息状态帕金森病中枢运动系统的功能网络连接，2006-01至2008.12

部分代表论文（*通讯作者）

1. Zhang D, ZhouL, Yao J, Shi Y, He H, Wei J, Tong Q, Liu J, Wu T*. Increased free water in theputamen in idiopathic REM sleep behaviour disorder. Mov Disord. 2023Sep;38(9):1645-1654, DOI: 10.1002/mds.29499

2. Sun J, MaJ, Gao L, Wang J, Zhang D, Chen L, Fang J, Feng T, Wu T*. Disruption of locus coeruleus-relatedfunctional networks in Parkinson's disease. NPJ Parkinsons Dis. 2023 May30;9(1):81. doi: 10.1038/s41531-023-00532-x.

3. ZhangD, Shi Y, Yao J, Zhou L, Wei H, Liu J, Tong Q, Ma L*, He H*, Wu T*. Free-waterimaging of the substantia nigra in GBA pathogenicvariant carriers. Mov Disord. 2023 May;38(5):764-773.doi: 10.1002/mds.29356.

4. WangJ, Sun L, Chen L, Sun J, Xie Y, Tian D, Gao L, Zhang D, Xia M*, Wu T*. Commonand Distinct Roles of Amygdala Subregional Functional Connectivity in Non-MotorSymptoms of Parkinson's Disease. NPJ Parkinsons Dis. 2023Feb 17;9(1):28. https://doi.org/10.1038/s41531-023-00469-1.

5. SuD, Gan Y, Zhang Z, Cui Y, Zhang Z, Liu Z, Wang Z, Zhou J, Sossi V, Stoessl AJ,Wu T*, Jing J*, Feng T*. Multimodal Imaging of Substantia Nigra in Parkinson'sDisease with Levodopa-Induced Dyskinesia. Mov Disord. 2023 Apr;38(4):616-625.doi: 10.1002/mds.29320.

6. WangJ, Sun J, Gao L, Zhang D, Chen L, Wu T*. Common and uniquedysconnectivity profiles of dorsal and median raphe in Parkinson's disease.Hum Brain Mapp. 2023 Feb 15;44(3):1070-1078. doi:10.1002/hbm.26139.

7. ZhangD, Zhou L, Shi Y, Liu J, Wei H, Tong Q, He H*, Wu T*. Increasedfree water in the substantia nigra in asymptomatic LRRK2 G2019S mutationcarriers. Mov Disord. 2023 Jan;38(1):138-142. doi: 10.1002/mds.29253.

8. SunJ, Lai Z, Ma J, Gao L, Chen M, Chen J, Fang J, Fan Y, Bao Y, Chan P, Yang Q, Ye C, Wu T*, Ma T*. Quantitative Evaluation of Iron Content in Idiopathic RapidEye Movement Sleep Behavior Disorder. Mov Disord. 2020;35(3):478-485.

9. WuT*, Zhang J, Hallett M, Feng T, Hou Y, Chan P. Neural correlates underlying micrographia in Parkinson's disease. Brain 2016;139(1):144-160.

10. GaoL, Wu X, Zhang J, Chan P, Wu T*. Brain activity in Parkinson’s disease patients with mild cognitive impairment. Science Bulletin. Sci. Bull. 2016;61(24):1876-1883.

11. WuT*, Hallett M. The Cerebellum in Parkinson's Disease. Brain 2013; 136:696-709.

12. WuT*, Wang L, Hallett M, Li K, Chan P. Neural correlates of bimanual anti-phase and in-phase movements in Parkinson's disease. Brain 2010;133:2394-2409.

13. WuT*, Hallett M. Neural correlates of dual task performance in patients with Parkinson’s disease. J Neurology Neurosurgery Psychiatry 2008;79:760-766.

14. Wu T,Hallett M*. A functional MRI study of automatic movements in patients with Parkinson’s disease. Brain 2005;128:2250-59.