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王天龙教授,现任首都医科大学宣武医院麻醉科主任以及麻醉教研室主任、主任医师、教授,博士研究生导师。1989年毕业于北京大学医学部医疗专业;2000年获得北京大学医学博士学位;2001年至2002年,赴加拿大蒙特利尔大学Notre-Dame医院接受博士后训练。主要研究方向包括:围术期脆弱脏器功能保护的基础与临床研究,老年患者麻醉及围术期大数据库的建立与质量改进。至今,已在国内外医学杂志发表研究论文超过400余篇,主编、主译、参编医学专著68部,参与中华麻醉学会指南制定21部。现担任中华麻醉学模拟教育培训基地主任;担任《中华麻醉学杂志》、《临床麻醉学杂志》、《中华医学杂志》、《北京医学》、《国际麻醉学与复苏杂志》、《Anesthesiology》中文版等20余种杂志的副总编、常务编委等。现为中华医学会麻醉学分会副主任委员,中华医学会麻醉学分会老年人麻醉学组组长,国家老年麻醉联盟(NAGA)主席,北京医学会麻醉学分会主任委员,欧洲麻醉与重症学会(ESAIC)考试委员会委员,中国医师学会麻醉医师分会常委,第二届中国医师协会毕业后医学教育麻醉学专业委员会副主任委员等社会任职。
宣武医院麻醉手术科是我国麻醉学界极具影响力的科室之一,是中华医学会麻醉学分会副主委单位、中华医学会老年人麻醉学组组长单位、中华医学会麻醉学分会老年人麻醉大数据库-北方中心,北京医学会麻醉学分会主委单位,是全国麻醉学住院医师规范化培训示范基地、中华麻醉学模拟教育培训基地,中华医学会麻醉学分会老年人麻醉培训基地。
目前科室团队共有麻醉医师79人,其中高级职称25人,中级职称25人,其中98%拥有硕士学位,35%拥有博士学位,近30人次在国外著名医学中心进行博士后训练及访问学习,多人获得北京市人才项目。手术室护士120余人,其中麻醉恢复室21人。工作区域遍布医院10个区域。尤其在神经外科(包括小儿癫痫外科等)、功能神经外科(包括脑起搏器置入、术中唤醒麻醉等)、介入、肾移植和老年危重症患者麻醉等方面独具特色。科室团队开展了“ 高龄患者围术期多学科评估与辅助决策系统(APPLE-MDT)”的软件构建,多学科评估工作稳步进行;并在妇产科、骨科、小儿神经外科、脊柱神经外科开展ERAS快速外科康复,加速患者康复及缩短住院天数;协助泌尿外科顺利完成肾移植手术,并成立肝、肺移植麻醉小组。截止2021年团队已协助心内科开展经股动脉主动脉瓣置换术和左心耳封堵术5例、60例。
1.2019年获得北京自然科学基金-面上项目-“人脐带间充质干细胞防治老龄大鼠内毒素血症后神经炎性认知功能障碍的机制”
2.2019年获得北京市属医学科研院所公益发展改革试点项目:老年患者围术期综合管理方案和创新技术研究。Beijing Municipal Health Commission (Jing2019-2)。
3.2021年获得首都医科大学宣武医院汇智人才计划(2021-2023)
1.2019年获得北京自然科学基金-面上项目-“人脐带间充质干细胞防治老龄大鼠内毒素血症后神经炎性认知功能障碍的机制”
2.2019年获得北京市属医学科研院所公益发展改革试点项目:老年患者围术期综合管理方案和创新技术研究。Beijing Municipal Health Commission (Jing2019-2)。
3.2021年获得首都医科大学宣武医院汇智人才计划(2021-2023)
一、主编或副主编的著作/ 译著:
1.《神经外科麻醉学》副主编 人民卫生出版社 2018
2.《姚氏麻醉学-问题为导向的病例讨论》第八版 主译 北京大学医学出版社 2018
3.《老年患者麻醉教程》 主译 世界图书出版上海有限公司 2018
4. 《摩根临床麻醉学》第六版中文版 主译 北京大学医学出版社 2020
5.《儿科麻醉学》 主编 2020
6.临床医疗护理常规《麻醉科诊疗常规》 主编 中国医药科技出版社 2019
7.《摩根临床麻醉学-病例精选》主译 北京大学医学出版社 2022
8.《2021麻醉学新进展.》(国家麻醉学专业继续医学教育教材)副主编 人民卫生出版社,2022
二、 重要学术论文
1BenhouZhang1,2†, Guifang Wang3†, Xiaopeng Liu2, Tian-Long Wang1*‡ and Ping Chi2*‡。 The Opioid-SparingEffect of Perioperative Dexmedetomidine Combined with Oxycodone Infusion duringOpen Hepatectomy: A Randomized Controlled Trial. Frontiers in Pharmacology. 2018 Jan4;8:940. doi: 10.3389/fphar.2017.00940.
2. 中华医学会外科学分会,中华医学会麻醉学分会(联合执笔人)。加速外科康复中国专家共识暨路径管理指南(2018)。中华麻醉学杂志,2018;38(1):8-33.
3. Meng L1, Gruenbaum SE2, Dai F3, Wang T4。Physiology,intervention, and outcome: three critical questions about cerebral tissueoxygen saturation monitoring. MinervaAnestesiol. 2018 Jan 17. doi: 10.23736/S0375-9393.18.12476-X.
4. 王天龙(述评)。老年患者围术期脆弱脏器保护-阻断或减弱脏器伤害性刺激。中华医学杂志,2018;98(10):721-722.
5. 马艳辉,吴洁,贾宾,薛纪秀,王天龙*。连续髂筋膜间隙阻滞联合口服镇痛药用于老年髋部骨折患者术前镇痛的效果。中华医学杂志,2018;98(10):721-722.723-727.
6.Miao FF1, Kong CC1, Wu Y2, Fan L1, Wang TL1. Golgi fragmentationinduced by overactivated cyclin-dependent kinase 5 is associated withisoflurane-induced neurotoxicity。Neuroreport. 2018 Mar 7;29(4):241-246. doi:10.1097/WNR.0000000000000931
7.杨舒仪,王天龙,肖玮。围术期抗炎措施对术后疼痛影响的研究进展。北京医学;2018:40(3):233-235.
8. Meng L1, Gruenbaum SE2, Dai F3, Wang T4。Physiology, intervention, and outcome: three criticalquestions about cerebral tissue oxygen saturation monitoring. MinervaAnestesiol. 2018 May;84(5):599-614. doi:10.23736/S0375-9393.18.12476-X. Epub 2018 Jan 17.
9. Lingzhong Meng, MD,* Jianjun Li, MD,† Alana M. Flexman, MD,‡ Chuanyao Tong, MD, PhD,§ ,XiangyongZhou, MD,∥ Adrian W. Gelb, MBChB,¶ Tianlong Wang, MD,#and David L. McDonagh, MD**††‡‡。Perceptionsof Perioperative Stroke Among Chinese Anesthesiologists: Starting a Long Marchto Eliminate This Underappreciated Complication。Anesth Analg.2018 Jul 21. doi: 10.1213/ANE.0000000000003677.
10. 王天龙 黄宇光。病例云查房:推动老年患者围术期管理不断提升。中华麻醉学杂志,2020;40(7):769-770.
11. 王天龙。述评:加快从围术期脑保护向围术期脑健康理念的转变。北京医学,2018;40(6):491.
12. 王天龙,徐娜。专家笔谈:脑电图联合无创脑氧饱和度监测实施目标导向围术期脑功能保护。北京医学;2018:;40(6):493-494.
13. 冯帅,肖玮,王天龙。目标导向液体治疗对小儿癫痫病灶切除术术后转归的影响。北京医学,2018;40(6):513-516.
14. YANHUI MA, JIE WU,JIXIU XUE, FEI LAN and TIANLONG WANG。Ultrasound‑guided continuousfascia iliaca compartment block for pre‑operative pain control in very elderlypatients with hip fracture: A randomized controlled trial。EXPERIMENTALAND THERAPEUTIC MEDICINE 16: 1944-1952, 2018。
15. Lingzhong Meng, Weifeng Yu, Tianlong Wang,Lina Zhang, Paul M. Heerdt, Adrian W. Gelb。BloodPressure Targets in Perioperative Care Provisional Considerations Based on aComprehensive Literature Review. Hypertension. 2018;72:00-00. DOI:10.1161/HYPERTENSIONAHA.118.11688.
16. Shuai Feng1†, Shuyi Yang1†, Wei Xiao1, Xue Wang2, Kun Yang3 and Tianlong Wang1*.Effects of perioperative goal-directed fluid therapy combinedwith the application of alpha-1 adrenergic agonists on postoperative outcomes:a systematic review and meta-analysis. BMC Anesthesiology, 2018 Aug 17;18(1):113. doi: 10.1186/s12871-018-0564-y.
17. Xiaohua Wang1,2,3, ZerongYou5, Guoguang Zhao2,3,4 & Tianlong Wang1,2,3。MicroRNA-194-5pLevels Decrease during Deep Hypothermic Circulatory Arrest. Sci Rep.2018 Sep 19;8(1):14044. doi: 10.1038/s41598-018-32426-x.
18. WangXH1, WangTL1. MicroRNAs of microglia: Wrestling with central nervoussystem disease. Neural Regen Res. 2018Dec;13(12):2067-2072. doi: 10.4103/1673-5374.241444.
19. ZhangM1, ZhangYH1, FuHQ1, ZhangQM2, WangTL1. Ulinastatin May Significantly Improve Postoperative CognitiveFunction of Elderly Patients Undergoing Spinal Surgery by Reducing theTranslocation of Lipopolysaccharide and Systemic Inflammation. Front Pharmacol. 2018 Oct 9;9:1007. doi:10.3389/fphar.2018.01007. eCollection 2018.
20. 王天龙*,黄宇光。述评:推动从麻醉学向围术期医学的转变-《快速外科康复中国专家共识暨临床路径指南》麻醉部分解读。协和医学杂志,2018;9(6):481-484.
21. 王天龙*,张宏。述评:围术期老年医学应成为老年麻醉学的努力方向。临床麻醉学杂志,2018;34(7):629-630.
22. Yu Wang1, Li Li2,Tianlong Wang1, Lei Zhao1, Hua Feng1, Qian Wang1, Long Fan1, Xuexin Feng1, WeiXiao1, and Kunpeng Feng1 . The Efficacy of Near-Infrared SpectroscopyMonitoring in Carotid Endarterectormy: A Prospective, Single-Center,Observational Study. Cell Transplantation.2019, Vol. 28(2) 170–175.
23. Feng G1, Sun B2, Liu HX1, Liu QH1, Zhao L1, Wang TL3。EphA2 antagonism alleviates LPS-inducedacute lung injury via Nrf2/HO-1, TLR4/MyD88 and RhoA/ROCK pathways. IntImmunopharmacol. 2019 Apr 12;72:176-185. doi: 10.1016/j.intimp.2019.04.008.
24. Zhang QL1, Wang L2, Xu MJ3, Wang TL4. Protective effect of dexmedetomidine onkidney injury of parturients with preeclampsia undergoing cesarean section: arandomized controlled study. Biosci Rep. 2019Apr 8. pii: BSR20190352. doi: 10.1042/BSR20190352.
27. Milton Raff . Anissa Belbachir . SalahEl-Tallawy . Kok Yuen Ho . Eric Nagtalon . Amar Salti . Jeong-Hwa Seo . AidaRosita Tantri . Hongwei Wang . Tianlong Wang . Kristal Cielo Buemio . ConsueloGutierrez . Yacine Hadjiat. Intravenous Oxycodone Versus Other IntravenousStrong Opioids for Acute Postoperative Pain Control: A Systematic Review ofRandomized Controlled Trials. Pain Ther https://doi.org/10.1007/s40122-019-0122-4.
32. Li Z1, Lan F2, Shen Y2, An S1, Xu N2, Yin C2, Yu W2, Ye W2, Cao G1, Wang T2.Prediction of the need for manipulation under anesthesia for flexioncontracture after total knee arthroplasty in patients of advanced age. JInt Med Res. 2019 May 30:300060519851328. doi:10.1177/0300060519851328. [Epub ahead of print]
33. Yang S1, Xiao W1, Wang S2, Meng L3, Zhou L2, Wan A2, Liu Y1, Feng S1, Wang T1,4. Parecoxib Shortens the Durationof Acute Postoperative Pain After Laparoscopic-Assisted Vaginal Hysterectomy. Front Pharmacol. 2019Jun 18;10:689. doi: 10.3389/fphar.2019.00689. eCollection 2019.
34. Kong C1, Miao F1, Wu Y2, Wang T3.Oxycodone suppresses the apoptosis of hippocampal neurons induced byoxygen-glucose deprivation/recovery through caspase-dependent andcaspase-independent pathways via κ- and δ-opioid receptors in rats. Brain Res. 2019 Jul 2:146319. doi:10.1016/j.brainres.2019.146319. [Epub ahead of print]
35. Wang XH1, Yao DX1, Luan XS1, Wang Y1, Liu HX1, Liu B1, Liu Y1, Zhao L1, Ji XM2, Wang TL1. MicroRNAexpression in the hippocampal CA1 region under deep hypothermic circulatoryarrest. Neural RegenRes. 2019 Nov;14(11):2003-2010. doi: 10.4103/1673-5374.253174.
36. 王天龙,王东信。述评:围术期脑状态的多学科调控是老年患者围术期脑健康的关键。中华医学杂志;2019;99(27):2081-2083.
37. 标准与规范中华医学会麻醉学分会老年人麻醉学组,国家老年疾病临床医学研究中心,中华医学会精神病学分会,国家睡眠研究中心,国家老年麻醉联盟(NAGA),中国心胸血管麻醉学会围术期器官保护学会。中国老年患者围术期脑健康多学科专家共识(一)。中华医学杂志。2019;99(27):2084-2110.
38. Wang X1,2, Zhang J1,2, Feng K1,2, Yang Y3, Qi W4, Martinez-VazquezP4, Zhao G1,2, Wang T1,2. Theeffect of hypothermia during cardiopulmonary bypass on three electro-encephalographicindices assessing analgesia and hypnosis during anesthesia: consciousnessindex, nociception index, and bispectral index. Perfusion. 2020Mar;35(2):154-162. doi: 10.1177/0267659119864821. Epub 2019 Aug 7.
39. 标准与规范中华医学会麻醉学分会老年人麻醉学组,国家老年疾病临床医学研究中心,中华医学会精神病学分会,国家睡眠研究中心,国家老年麻醉联盟(NAGA),中国心胸血管麻醉学会围术期器官保护学会。中国老年患者围术期脑健康多学科专家共识(二)。中华医学杂志,2019;99(29):2252-2269.
40. Wang X, Feng K, Liu H, Liu Y, Ye M, Zhao G, Wang T*. Regionalcerebral oxygen saturation and postoperative delirium in endovascular surgery:a prospective cohort study. Trials. 2019 Aug 14;20(1):504. doi:10.1186/s13063-019-3586-y.
41. MengLi, Tianlong Wang*, Wei Xiao, Lei Zhao and Dongxu Yao。Low-Dose Dexmedetomidine AcceleratesGastrointestinal Function Recovery in Patients Undergoing Lumbar Spinal Fusion。Front Pharmacol. 2019Dec 19;10:1509. doi: 10.3389/fphar.2019.01509. eCollection 2019.
42. 标准与规范中华医学会麻醉学分会老年人麻醉学组,国家老年疾病临床医学研究中心,中华医学会精神病学分会,国家睡眠研究中心,国家老年麻醉联盟(NAGA),中国心胸血管麻醉学会围术期器官保护学会。中国老年患者围术期脑健康多学科专家共识(三)。中华医学杂志;2019;99(31):2409-2422.
43. 王天龙*。加速康复外科理念在胸科手术围术期肺保护的应用。北京医学,2019;41(8):632.
44.LingxueZhou, Long Fan, Cuicui Konga, Fangfang Miaoa, Yan Wub and Tianlong Wanga. Oxycodone suppresses thelipopolysaccharide-induced neuroinflammation by downregulating nuclear factor-Κb in hippocampal astrocytes ofSprague–Dawley rats. Neuroreport.2020 Jan 27;31(2):99-108. doi: 10.1097/WNR.0000000000001376.
45. 王天龙。新型冠状病毒肺炎患者的麻醉管理与感染控制的思考。北京医学,2020;32(3):282-283.
46. Wenchao Zhang 1, Tianlong Wang 2, Geng Wang 1, Yi Yuan 1, Yan Zhou 1, Xiaoyu Yang 1, Minghui Yang 3, Shaoqiang Zheng 1。ElevatedLateral Position Improves the Success of Paramedian Approach SubarachnoidPuncture in Spinal Anesthesia before Hip Fracture Surgery in Elderly Patients:A Randomized Controlled Study。MedSci Monit. 2020 Aug 6;26:e923813. doi:10.12659/MSM.923813.
47. 王天龙(述评)。维护老年患者内环境稳定与代偿状态是围手术期管理之核心。中华医学杂志,2020;100(31):2401-2402.
48.标准与规范 中华医学会麻醉学分会老年人麻醉学组国家老年疾病临床医学研究中心 国家老年麻醉联盟。中国老年患者围术期麻醉管理指导意见(2020版)(一)。中华医学杂志,2020;100(31):2404-2415.
49. Wenchao Zhang , Tianlong Wang*, Geng Wang , Minghui Yang, Yan Zhou , Yi Yuan。Effectsof Dexmedetomidine on Postoperative Delirium and Expression of IL-1β, IL-6, andTNF-α in Elderly Patients After Hip Fracture Operation. FrontPharmacol. 2020 May 12;11:678. doi:10.3389/fphar.2020.00678. eCollection 2020.
50. Xiaohua Wang 1 2 3, Ke Huang 4 5 6, Hao Yan 7, Fei Lan 4 5 6, Dongxu Yao 4 5 6, Yanhong Li 4 5 6, Jixiu Xue 4 5 6, Tianlong Wang 8 9 10.The median effective dose (ED50) of cis-Atracurium forlaryngeal mask airway insertion during general Anaesthesia for patientsundergoing urinary surgery. BMC Anesthesiol. 2020 Mar19;20(1):68. doi:10.1186/s12871-020-00982-3.
51. 标准与规范 中华医学会麻醉学分会老年人麻醉学组国家老年疾病临床医学研究中心 国家老年麻醉联盟。中国老年患者围术期麻醉管理指导意见(2020版)(二)。中华医学杂志,2020;100(33):2565-2578.
52. Kunpeng Feng1,2, Xiaohua Wang1,2, Xuexin Feng1,2, JinfengZhang3, Wei Xiao1,2, Fengying Wang4, Qi Zhou4 and Tianlong Wang1,2*。Effects of continuous infusion of phenylephrine vs. norepinephrine on parturients and fetuses underLiDCOrapid monitoring: a randomized, double-blind, placebo-controlled study.BMC Anesthesiology; (2020) 20:229. https://doi.org/10.1186/s12871-020-01145-0.
53. 标准与规范 中华医学会麻醉学分会老年人麻醉学组 国家老年疾病临床医学研究中心 国家老年麻醉联盟。中国老年患者围术期麻醉管理指导意见(2020版)(三)。中华医学杂志,2020;100(34):2645-2651.
54. 标准与规范 中华医学会麻醉学分会老年人麻醉学组 国家老年疾病临床医学研究中心 国家老年麻醉联盟。中国老年患者围术期麻醉管理指导意见(2020版)(四)。中华医学杂志,2020;100(35):2736-2757.
55. Min Li, Tian-Long Wang*, Dong-Xin Wang*。An overview of Chinesemultidisciplinary expert consensus on perioperative brain health in elderlypatients. Chinese MedicalJournal 2020;Vol(No). DOI:10.1097/CM9.0000000000001213.
56. 冯帅,兰飞,赵磊,王东信,王锷,张宏,马虹,薛张刚,王天龙,黄宇光。高龄患者二尖瓣置换术后多节段椎体融合术麻醉与围术期管理。中华麻醉学杂志,2020;40(7):779-782。
57. Yang Liu, Hui-Qun Fu, Yan Wu, Zun-Shu Du, Bo-Ran Li, Xin Gao,Guan-Wen Lin, Shu-Yi Yang, Tian-Long Wang*。Influence of three different anesthesia protocols on agedrat brain: a resting-state functional magnetic resonance imaging study。Chinese Medical Journal2020;Vol(No). DOI:10.1097/CM9.0000000000001126.
58. Fei Lan 1, Guanwen Lin 1 2, Guanglei Cao 3, Zheng Li 3,Daqing Ma 4, Fangyan Liu 1, Mei Duan 1, Huiqun Fu 1, Wei Xiao 1, Zhigang Qi 5,Tianlong Wang 1*。Altered Intrinsic Brain Activity and Functional ConnectivityBefore and After Knee Arthroplasty in the Elderly: A Resting-State fMRI Study. FrontNeurol. 2020 Sep 29;11:556028. doi: 10.3389/fneur.2020.556028. eCollection2020.
59. Ning Zhang 1, Weiguang Ye 2, Tianlong Wang 2, Hui Wen 1, LanYao 3. Up-regulation of miR-106a targets LIMK1 and contributes to cognitiveimpairment induced by isoflurane anesthesia in mice. Genes Genomics. 2020Apr;42(4):405-412. doi: 10.1007/s13258-019-00913-8. Epub 2020 Jan 13.
60. 王天龙, 李民,李金宝。围手术期综合干预是确保老年患者膝关节术后长期心身健康的基础。中华医学杂志,2020;45(100):3559-3561.
61.标准与规范 中华医学会麻醉学分会老年人麻醉学组,中华医学会麻醉学分会骨科麻醉学组,国家老年疾病临床医学研究中心,国家老年麻醉联盟。中国老年患者膝关节手术围手术期麻醉管理指导意见(2020版)。中华医学杂志,2020;45(100):3566-3577.
62.王天龙。推动高龄高危患者全麻下的重症治疗。临床麻醉学杂志,2020;36(10):941-943.
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64.Fangfang Miao, Kunpeng Feng, Xuexin Feng, Long Fan, Yu Lang,Qingfang Duan,Ruixue Hou, Di Jin and Tianlong Wang*. The Analgesic Effect ofDifferent Concentrations of Epidural Ropivacaine Alone or Combined With Sufentanilin Patients After Cesarean Section. Frontier in Pharmacology, 2021. doi:10.3389/fphar.2021.631897.
65. 张芳 王东信 薛张刚 黄文起 马正良 尹春琳 王晟 李金宝 肖玮 王天龙 黄宇光。合并心肺功能不全高龄患者有半截常切除术的麻醉与围术期管理。中华麻醉学杂志,2020;40(8):902-906.
66. 张艳红① 赵国光① 李小莹① 王朝东① 王天龙① 鲁世保① 冀冰心① 贾 茜①。多学科协作在高龄骨科患者围术期全程管理中的应用。中国病案;2020;21(12):44-46.
67. YanhongZhang1,2, Lina Ma3, Tianlong Wang4, Wei Xiao4, Shibao Lu5, Chao Kong5, ChaodongWang2, Xiaoying Li1,Yun Li3, Chunlin Yin6, Suying Yan7, Ying Li8, Kun Yang9,Piu Chan2,10,11* and APPLE-MDT Study Working Group. Protocol for evaluation ofperioperative risk in patients aged over 75 years: Aged Patient PerioperativeLongitudinal Evaluation–Multidisciplinary Trial (APPLEMDT study). BMCGeriatrics; 2021; 21:14. https://doi.org/10.1186/s12877-020-01956-3.
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72. Mei Duan 1, Fangyan Liu 1, Huiqun Fu 1, Shibao Lu 2, Tianlong Wang 1. reoperativeMicrobiomes and Intestinal Barrier Function Can Differentiate ProdromalAlzheimer's Disease From Normal Neurocognition in Elderly Patients Scheduled toUndergo Orthopedic Surgery. Front Cell Infect Microbiol. 2021 Mar29;11:592842. doi: 0.3389/fcimb.2021.592842. eCollection 2021.
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三 重要奖项
1.中国医院协会创新奖3等奖 2021
2.医促会华夏奖-卫生管理奖 2021
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