近五年作为第一作者/共同一作或独立通讯作者发表 SCI 论文64篇，合计影响因子 287.75，单篇最高影响因子12.70。

申报专利19项（第一发明人申报9项），其中作为第一发明人已获得专利授权5项。

1.  Yang H, Wang Z, Jiang C, Zhang Y, Zhang Y, Xu M, Zhang Y, Wang Y, Liu X, An Z*, Tong Z*. Oral azvudine for mild-to-moderate COVID-19 in high risk, nonhospitalized adults: Results of a real-world study. J Med Virol. 2023 Jul;95(7):e28947. doi: 10.1002/jmv.28947.   （IF:12.7）    

2.  Yang H*, Wang Z*, Zhang Y, Xu M, Wang Y, Zhang Y, Liu X, An Z*, Tong Z*. Clinical characteristics and factors for serious outcomes among outpatients infected with the Omicron subvariant BF.7. J Med Virol. 2023 Aug;95(8):e28977. doi: 10.1002/jmv.28977.        （IF:12.7）    

3.  Wang X, Ye Z, Busse JW, Hill MD, Smith EE*, Guyatt GH, Prasad K, Lindsay MP, Yang H, Zhang Y, Liu Y, Tang B, Wang X, Wang Y, Couban RJ, An Z*. Endovascular thrombectomy with or without intravenous alteplase for acute ischemic stroke due to large vessel occlusion: a systematic review and meta-analysis of randomized trials. Stroke Vasc Neurol. 2022 Jun 20:svn-2022-001547. doi: 10.1136/svn-2022-001547.     （IF:9.893）  

4. Xuan L, Ren L, Zhang W, Du P, Li B, An Z*. Formaldehyde aggravates airway inflammation through induction of glycolysis in an experimental model of asthma exacerbated by lipopolysaccharide. Sci Total Environ. 2024 Feb 20;912:168947. doi: 10.1016/j.scitotenv.2023.168947.    （IF:9.8）      

5.  Zhao R#, An Z#, Sun Y, Xia L, Qiu L, Yao A, Liu Y*, Liu L*. Metabolic profiling in early pregnancy and associated factors of folate supplementation: A cross-sectional study. Clin Nutr. 2021 Sep;40(9):5053-5061. doi: 10.1016/j.clnu.2021.01.012.      （IF:7.324）  

6.  Ma Z#, Sun X#, Zhang Y, Li H, Sun D, An Z*, Zhang Y*. Risk of Thromboembolic Events in Cancer Patients Treated with Immune Checkpoint Inhibitors: A Meta-analysis of Randomized Controlled Trials. Thromb Haemost. 2022 Jun 30. doi: 10.1055/s-0042-1749185.      （IF:6.681）  

7.  Ye Z, Busse JW, Hill MD, Lindsay MP, Guyatt GH, Prasad K, Agarwal A, Beattie C, Beattie J, Dodd C, Heran MKS, Narayan S, Chartúir NN, O'Donnell M, Resmini I, Sacco S, Sylaja PN, Volders D, Wang X, Xie F, Zachrison KS, Zhang L, Zhong H, An Z*, Smith EE. Endovascular thrombectomy and intravenous alteplase in patients with acute ischemic stroke due to large vessel occlusion: A clinical practice guideline. J Evid Based Med. 2022 Sep;15(3):263-271. doi: 10.1111/jebm.12493.        （IF:6.224）  

8.  Du P*, Wang G, Hu T, Li H, An Z*. Integration Analysis of Pharmacokinetics and Metabolomics to Predict Metabolic Phenotype and Drug Exposure of Remdesivir. Front Pharmacol. 2022 Jan 5;12:779135. doi: 10.3389/fphar.2021.779135.    （IF:5.988）

9.   An Z#, Zhao R#, Han F, Sun Y, Liu Y*, Liu L*. Potential Serum Biomarkers Associated with Premature Rupture of Fetal Membranes in the First Trimester. Front Pharmacol. 2022 Jul 8;13:915935. doi: 10.3389/fphar.2022.915935.     （IF:5.988）

10. Hu T*, Sun Y, An Z*. Dose- and time-dependent manners of moxifloxacin induced liver injury by targeted metabolomics study. Front Pharmacol. 2022 Sep 16;13:994821. doi: 10.3389/fphar.2022.994821.    （IF:5.988）  

11. Wang X, Turhon M, Yang X, Liu J, Zhang H, Li T, Song D, Zhao Y, Guan S, Maimaitili A, Wang Y, Feng W, Wan J, Mao G, Shi H, An Z*, Wang Y*. Could statin improve outcomes after pipeline embolization for intracranial aneurysms in a real-world setting? Ther Adv Neurol Disord. 2023 May 10;16: 17562864231170517. doi: 10.1177/17562864231170517.       （IF:5.9）      

12. Hu T*, Zhang W, Han F, Zhao R, Liu L, An Z*. Plasma fingerprint of free fatty acids and their correlations with the traditional cardiac biomarkers in patients with type 2 diabetes complicated by coronary heart disease. Front Cardiovasc Med. 2022 Jul 22;9:903412. doi: 10.3389/fcvm.2022.903412.     （IF:5.846）  

13. Ren L#, Xuan L#, Li A#, Yang Y, Zhang W, Zhang J, Zhang Y, An Z*. Gamma-aminobutyric acid supplementation improves olanzapine-induced insulin resistance by inhibiting macrophage infiltration in mice subcutaneous adipose tissue. Diabetes Obes Metab. 2024 Jul;26(7):2695-2705. doi: 10.1111/dom.15585.    （IF:5.8）      

14. Yang H, Yu X, An Z*. Cutaneous Toxicity Associated With Enfortumab Vedotin: A Real-Word Study Leveraging U.S. Food and Drug Administration Adverse Event Reporting System. Front Oncol. 2022 Jan 19;11:801199. doi: 10.3389/fonc.2021.801199.   （IF:5.738）

15. Hu Y#, Lu W#, Tang B, Zhao Z*, An Z*. Urinary incontinence as a possible signal of neuromuscular toxicity during immune checkpoint inhibitor treatment: Case report and retrospective pharmacovigilance study. Front Oncol. 2022 Sep 12;12:954468. doi: 10.3389/fonc.2022.954468.      （IF:5.738）

16. Zhang Y, Ran L, Liang Y, Zhang Y, An Z*. Safety analysis of pemigatinib leveraging the US Food and Drug administration adverse event reporting system. Front Pharmacol. 2023 Jul 24;14:1194545. doi: 10.3389/fphar.2023.1194545.      （IF:5.6）      

17. Yang H, Wang Z, Zhang Y, Xu M, Wang Y, Zhang Y, An Z*, Tong Z*. Effectiveness of inactivated COVID-19 vaccines against SARS-CoV-2 Omicron subvariant BF.7 among outpatients in Beijing, China. Vaccine. 2023 Nov 22;41(48):7201-7205. doi: 10.1016/j.vaccine.2023.10.036.   （IF:5.5）      

18. Du P*, Xuan L, An Z*, Zhang Y*. Development and validation of a robust and sensitive HPLC-MS/MS method for the quantitation of MRTX849 in plasma and its application in pharmacokinetics. Analyst. 2022 Mar 14;147(6):1175-1180. doi: 10.1039/d1an01928g.        （IF:5.227)  

19. Cong L†, Wan Z†, Li P†, Liu D, He J*, An Z*, Liu L. Metabolic, genetic, and pharmacokinetic parameters for the prediction of olanzapine efficacy. Eur J Pharm Sci. 2022 Aug 15:106277. doi: 10.1016/j.ejps.2022.106277.     (IF:5.112)

20. Hu T, Zhang W, Han F, Zhao R, Liu H, An Z*. Machine learning reveals serum myristic acid, palmitic acid and heptanoylcarnitine as biomarkers of coronary artery disease risk in patients with type 2 diabetes mellitus. Clin Chim Acta. 2024 Mar 15;556:117852. doi: 10.1016/j.cca.2024.117852.      (IF:5)  

21. Yang H, Yu X, Hou W, Liu X, Chen J, Zhang Y, Wang Y, Zhu Y, Qian Q, Ma K, An Z*. Effectiveness and safety of nirmatrelvir-ritonavir in kidney transplant recipients with severe kidney dysfunction infected with COVID-19. Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0138423. doi: 10.1128/aac.01384-23.    （IF:4.9）      

22. Hu T#, An Z#, Sun Y, Wang X, Du P, Li P, Chi Y*, Liu L*. Longitudinal Pharmacometabonomics for Predicting Malignant Tumor Patient Responses to Anlotinib Therapy: Phenotype, Efficacy, and Toxicity. Front Oncol. 2020 Nov 12;10:548300. doi: 10.3389/fonc.2020.548300.      （IF:4.848）  

23. Hu T, Sun Y, Li H, Du P, Liu L*, An Z*. Dual derivatization strategy for the comprehensive quantification and double bond location characterization of fatty acids by ultra-high performance liquid chromatography-tandem mass spectrometry. J Chromatogr A. 2021 Feb 22;1639:461939. doi: 10.1016/j.chroma.2021.461939.       （IF:4.759）

24. Wang X#, Wang C#, Zhang Y*, An Z*. Effect of pharmacogenomics testing guiding on clinical outcomes in major depressive disorder: a systematic review and meta-analysis of RCT. BMC Psychiatry. 2023 May 12;23(1):334. doi: 10.1186/s12888-023-04756-2.        （IF:4.4）

25. Sun X#, Wang H#, Zhan X, Yan Y, Chen K, An Z*, Zhou H*. Comparison of the safety profiles for pirfenidone and nintedanib: a disproportionality analysis of the US food and drug administration adverse event reporting system. Front Pharmacol. 2024 May 27;15:1256649. doi: 10.3389/fphar.2024.1256649.      （IF:4.4）      

26. Hu T#*, Li H#, Xu B, Du P, Liu L, An Z*. Parallel derivatization strategy for comprehensive profiling of unconjugated and glycine-conjugated bile acids using Ultra-high performance liquid chromatography-tandem mass spectrometry. J Steroid Biochem Mol Biol. 2021 Nov;214:105986. doi: 10.1016/j.jsbmb.2021.105986.        （IF:4.292）

27. Zhang Y#, Ma Z#, Sun X, Feng X*, An Z*. Interstitial lung disease in patients treated with Cyclin-Dependent Kinase 4/6 inhibitors: A systematic review and meta-analysis of randomized controlled trials. Breast. 2022 Apr;62:162-169. doi: 10.1016/j.breast.2022.02.011. （IF:4.254）  

28. Ma Z, Zhang Y, Zhu M, Feng L, Zhang Y*, An Z*. Interstitial lung disease associated with anti-HER2 anti-body drug conjugates: results from clinical trials and the WHO's pharmacovigilance database. Expert Rev Clin Pharmacol. 2022 Nov;15(11):1351-1361. doi: 10.1080/17512433.2022.2121705.    （IF:4.108）  

29.  Hu T#*, Ren L#, Li H, An Z*. Effects of Vitamin D supplementation or deficiency on metabolic phenotypes in mice of different sexes. J Steroid Biochem Mol Biol. 2023 May;229:106250. doi: 10.1016/j.jsbmb.2023.106250.   （IF:4.1）      

30. Wang X#, Zhang Y#, Huang C, Yang H, Jiang C, Yu X, Zhao R, Hong J, Zhang Y, Wang Y, Zhao R, An Z*, Tong Z*. Booster vaccines dose reduced mortality in hospitalized COVID-19 patients requiring oxygen supplementation: Evidence from the Beijing Omicron outbreak. Hum Vaccin Immunother. 2024 Dec 31;20(1):2361500. doi: 10.1080/21645515.2024.2361500. Epub 2024 Jun 21.       （IF:4.1）      

31. An Z#, Wang X#, Li P#, He J, Liu L*. Exploring the metabolic characteristics and pharmacokinetic variation of paroxetine in healthy volunteers using a pharmacometabonomic approach. J Pharm Biomed Anal. 2021 Sep 10;204:114224. doi: 10.1016/j.jpba.2021.114224.    （IF:3.935）  

32. Zhou H#, Sun X#, Lyu S, Yu X, Li R, Wang H*, An Z*. Evaluation of Tigecycline Utilization and Trends in Antibacterial Resistance from 2018 to 2021 in a Comprehensive Teaching Hospital in China. Infect Drug Resist. 2023 Feb 14;16:879-889. doi: 10.2147/IDR.S395158.       （IF:3.9）

33. Zhang J, Han L, Liu H, Zhang H*, An Z*. Metabolomic analysis reveals the metabolic disturbance in aortic dissection: Subtype difference and accurate diagnosis. Nutr Metab Cardiovasc Dis. 2023 Aug;33(8):1556-1564. doi: 10.1016/j.numecd.2023.05.006.       （IF:3.9）      

34. Liu H#, Zhao Z#, Wang Y, Liu L, Yang Y, An Z*. Study on the Relationship between Rivaroxaban and Factor Xa Activity in Blood Based on HPLC-MS/MS. Curr Drug Metab. 2021;22(14):1132-1138. doi: 10.2174/1389200222666211126093627.      （IF:3.731）  

35. Tang B#, Zhang Y#, Wang Y, Wang X, An Z*, Yu X*. Effect of bariatric surgery on long-term cardiovascular outcomes: a systematic review and meta-analysis of population-based cohort studies. Surg Obes Relat Dis. 2022 May 16:S1550-7289(22)00202-7. doi: 10.1016/j.soard.2022.05.007.       （IF:3.709）  

36. Xu M, Ma Z, Feng X, An Z*. Comparison of four criteria for potentially inappropriate medications in older patients with newly diagnosed non-small cell lung cancer. Expert Opin Drug Saf. 2024 May 22:1-7. doi: 10.1080/14740338.2024.2348567.   （IF:3.6）      

37. Wang X, Luo L, Wang Y, An Z*. Effect of Platelet Function Testing Guidance on Clinical Outcomes for Patients with Intracranial Aneurysms Undergoing Endovascular Treatment. AJNR Am J Neuroradiol. 2023 Aug;44(8):928-933. doi: 10.3174/ajnr.A7923.        （IF:3.5）      

38. Sun Y, Cong L, Yang S, Zhao R, An Z*, Liu L*. Moxifloxacin Induced Liver Injury by Causing Lachnospiraceae Deficiency and Interfering with Butyric Acid Production through Gut-Liver Axis. Dis Markers. 2022 Apr 29;2022:9302733. doi: 10.1155/2022/9302733. （IF:3.464）  

39. Hu T#, An Z#, Li H, Liu Y, Xia L, Qiu L, Yao A, Ma L*, Liu L*. UHPLC-MS/MS-Based Metabolomics and Clinical Phenotypes Analysis Reveal Broad-Scale Perturbations in Early Pregnancy Related to Gestational Diabetes Mellitus. Dis Markers. 2022 Aug 24;2022:4231031. doi: 10.1155/2022/4231031.   （IF:3.464）  

40. Yang H, Zhang Y, Wang Z, Xu M, Wang Y, Zhang Y, Feng X, An Z*. Adherence and recommended optimal treatment to Azvudine application for the treatment of outpatient COVID-19 patients: A real-world retrospective study. Heliyon. 2024 May 4;10(9):e30619. doi: 10.1016/j.heliyon.2024.e30619.       （IF:3.4）      

41. Hu T, Shi C, Liu L, Li P, Sun Y, An Z*. A single-injection targeted metabolomics profiling method for determination of biomarkers to reflect tripterygium glycosides efficacy and toxicity. Toxicol Appl Pharmacol. 2020 Jan 15;389:114880. doi: 10.1016/j.taap.2020.114880.    （IF:3.347）

42. Hu T#, An Z#, Shi C, Li P, Liu L*. A sensitive and efficient method for simultaneous profiling of bile acids and fatty acids by UPLC-MS/MS. J Pharm Biomed Anal. 2020 Jan 30;178:112815. doi: 10.1016/j.jpba.2019.112815.    （IF:3.209）  

43. An Z, Hu T, Lv Y, Li P, Liu L*. Targeted amino acid and related amines analysis based on iTRAQ®-LC-MS/MS for discovering potential hepatotoxicity biomarkers. J Pharm Biomed Anal. 2020 Jan 30;178:112812. doi: 10.1016/j.jpba.2019.112812. （IF:3.209）  

44. Yang H, Zhang Y, Feng X*, An Z*. Bleeding Complications in Vancomycin-Induced Thrombocytopenia: A Real-world Postmarketing Pharmacovigilance Analysis. Clin Ther. 2023 Sep;45(9):868-872. doi: 10.1016/j.clinthera.2023.06.022.   （IF:3.2）

45. Yang H, Wang Z, Wang C, Zhang Y, Han S, An Z*. Cost-effectiveness of Azvudine for High-risk Outpatients with Mild-to-moderate Coronavirus Disease 2019 in China. Clin Ther. 2024 Sep;46(9):e1-e5. doi: 10.1016/j.clinthera.2024.07.009.       （IF:3.2）      

46. Liu D#, An Z#, Li P, Chen Y, Zhang R, Liu L*, He J*, Abliz Z. A targeted neurotransmitter quantification and nontargeted metabolic profiling method for pharmacometabolomics analysis of olanzapine by using UPLC-HRMS. RSC Adv. 2020 May 13;10(31):18305-18314. doi: 10.1039/d0ra02406f.     （IF:3.119）  

47. Ma Z, Pei J, Zhang Y, Li H, Sun D, Zhang Y*, An Z*. Interstitial pneumonitis associated with EGFR/ ALK tyrosine kinase inhibitors used in non-small cell lung cancer: an observational, retrospective, pharmacovigilance study. Expert Opin Drug Saf. 2023 Mar;22(3):237-242. doi: 10.1080/14740338.2022.2110235.        （IF:3.1）

48. Jian Y, Han F, Zhu Y, Geng C, Zhang Y, Wu Y, Leng Y, Chen W, An Z*, Zhu H*. Paired comparisons of venetoclax concentration in cerebrospinal fluid, bone marrow, and plasma in acute leukemia patients. Clin Transl Sci. 2024 Sep;17(9):e70006. doi: 10.1111/cts.70006.     （IF:3.1）

49. Zhang Y, Ma K, Hou W, Liu X, Chen J, Wang Y, Zhu Y, Qian Q, An Z*, Yang H*. Inappropriate prescribing of Nirmatrelvir/Ritonavir in Solid Organ Transplantation with COVID-19 Infection: A Multicenter Retrospective Study. Clin Transl Sci.  （IF:3.1）

50. Li B, Yang S, Ye J, Chu S, Chen N*, An Z*. Flavin-containing monooxygenase 1 deficiency promotes neuroinflammation in dopaminergic neurons in mice. Neurosci Lett. 2021 Nov 1;764:136222. doi: 10.1016/j.neulet.2021.136222.      （IF:3.046）

51. Yang H, Ding Z, An Z*. Urinary tract infection following the use of BTK inhibitors: a real-world analysis of post-marketing surveillance data. Expert Opin Drug Saf. 2024 Mar;23(3):333-338. doi: 10.1080/14740338.2023.2251376.  （IF:3）  

52. Yang J, Yang H, An Z*. Catatonia related to tacrolimus: a real world pharmacovigilance study of FDA adverse event reporting system (FAERS) database. Expert Opin Drug Saf. Published online August 21, 2024. doi:10.1080/14740338.2024.2393757   （IF:3）

53. Zhang Y#, Ma Z#, Sun X, Zhang Y, Zhu M, Zhang S, Feng X, An Z*. Anticancer drug-induced interstitial lung disease: a critical appraisal of clinical practice guidelines and consensus statements. Expert Opin Drug Saf. 2024 Feb 20:1-9. doi: 10.1080/14740338.2024.2315113.   （IF:3）  

54. Wang X, Yang H, An Z*. Tacrolimus related diabetic ketoacidosis and hyperglycaemic hyperosmolar nonketotic syndrome: an observational, retrospective, pharmacovigilance study. Expert Opin Drug Saf. 2024 Aug 19:1-6. doi: 10.1080/14740338.2024.2393278.        （IF:3）

55. An Z, Li C, Lv Y, Li P, Wu C, Liu L*. Metabolomics of Hydrazine-Induced Hepatotoxicity in Rats for Discovering Potential Biomarkers. Dis Markers. 2018 Apr 10;2018:8473161. doi: 10.1155/2018/8473161.    （IF:2.949）

56. Zhang Y#, Wang X#, Huang C, Yang H, Jiang C, Yu X, Hong J, Zhang Y, Wang Y, Zhao R, An Z*, Tong Z*. Nirmatrelvir-Ritonavir Reduced Mortality in Hospitalized Patients with COVID-19 During the Omicron Outbreak: Real-World Evidence from Beijing. Infect Drug Resist. 2024 Apr 8;17:1367-1377. doi: 10.2147/IDR.S445826.       （IF:2.9）      

57. Li B, Liu M, Wang Y, Zhang H, Xuan L, Huang K, An Z*. Association of Severe Vitamin D Deficiency with Hospitalization in the Previous Year in Hospitalized Exacerbated COPD Patients. Int J Chron Obstruct Pulmon Dis. 2024 Jun 25;19:1471-1478. doi: 10.2147/COPD.S461029.   （IF:2.7）

58. Hu T,Han F, An Z*.Comprehensive profiling of serum glycosphingolipids to discover the diagnostic biomarkers of lung cancer and uncover the variation of glycosphingolipids network in different lung cancer subtypes.Anal Methods.     （IF:2.7）      

59.  An Z*, Sun Y, Shi C, Liu L*. Metabonomic and transcriptomic analyses of Tripterygium glycosides tablet-induced hepatotoxicity in rats. Drug Chem Toxicol. 2022 May 23:1-15. doi: 10.1080/01480545.2022.2077360. （IF:2.597）  

60. Hu T#*, Li H#, Liu H, Cong L, Liu L, An Z*. High throughput UHPLC-MS/MS method for the simultaneous quantification of six vitamin D metabolites: application for vitamin D determination in patients after liver or kidney transplantation. Anal Methods. 2020 Dec 7;12(46):5591-5600. doi: 10.1039/d0ay01088j.    （IF:2.596）

61. An Z*, Shi C, Li P, Liu L*. Stability of amino acids and related amines in human serum under different preprocessing and pre-storage conditions based on iTRAQ®-LC-MS/MS. Biol Open. 2021 Feb 26;10(2):bio055020. doi: 10.1242/bio.055020.      （IF:2.422）

62. Wang X, Tang B, Liu Y, Wang X, Wang S, An Z*, Wang H*. Clinical practice guidelines for management of dual antiplatelet therapy in patients with noncardiac surgery: A critical appraisal using the AGREE II instrument. J Clin Pharm Ther. 2022 May;47(5):652-661. doi: 10.1111/jcpt.13593.   （IF:2.145）  

63. Liu H, Yu X, Hu T, Han F, An Z*, Zhao R*. Simultaneous determination of four antibiotics in human plasma by high-performance LC-MS/MS: application to therapeutic drug monitoring. Bioanalysis. 2023 Mar;15(5):269-282. doi: 10.4155/bio-2023-0020. （IF:1.8）

64. Han F, Liu H,Hu T, Li P, Zhao R, An Z*.Development and validation of a rapid HPLC-MS/MS method for simultaneous determination of cyclosporine A and tacrolimus in whole blood for routine therapeutic drug monitoring in organ transplantation.Rapid Commun Mass Spectrom.   （IF:1.8）