附属北京佑安医院-黄晓婕导师介绍

更新于 2023-10-14 导师主页
黄晓婕 教授 硕,博士生导师
附属北京佑安医院
内科学(传染病)
艾滋病临床及基础研究,艾滋病抗病毒治疗联合免疫治疗研究,艾滋病微生物及其他组学研究
huangxiaojie78@126.com

黄晓婕,首都医科大学博士,1978年6月生人,主任医师,教授,博导,留英留美(牛津大学及洛克菲勒大学)访问学者。学术任职:中国研究型医院感染病学专委会常委兼秘书长;中国性病艾滋病协会青年专委会常务委员,艾滋病多学科专委会委员,中华医学会北京感染病学分会委员,北京市感染质量控制中心专家委员,中华中医药学会防治艾滋病分会第五届委员会常务委员。北京市科学技术委员会科技专家库评审专家,首都卫生发展专项基金评审专家,教育部评审专家。2022年入选重大传染病疫情的全球卫生治理方向高层次公共卫生技术人才(学科带头人),2020年入选北京市百千万人才工程(中青年领军人才),2019年入选北京市优秀人才青年拔尖人才项目。

于首都医科大学附属北京佑安医院工作20年,主要研究方向为各种感染性疾病临床及基础研究,艾滋病抗病毒治疗及机会性感染诊治。2014年由国家卫健委委派,作为援非专家赴几内亚抗击埃博拉,获得“中华之光”援非集体奖;2022年由国家卫健委委派,作为传染病领域专家对口支援大凉山美姑县人民医院开展艾滋病-结核-丙肝-梅毒四病同防同治援助工作。

科研方面,以负责人承担国家十三五传染病重大专项子课题、国家自然科学基金、首发基金及国际合作等多项国家科研项目,课题经费超1500万元; 发表中英文章160余篇,第一/通讯作者在JAMA Network Open, Journal of AIDS, Journal of Infectious Diseases, Pharmacological Research, Frontiers in immunology上发表SCI 收录论文60篇,累计影响因子380分。2012年及2013年荣获“首都十大疾病重大科技成果奖”两项;获得2019年度北京市“科学技术奖科技进步奖”二等奖1项。


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科研项目

一、人才项目

1.高层次公共卫生技术人才建设项目(学科带头人) 2023

2.北京市百千万人才工程项目(领军人才)2021

3.北京市优秀人才(青年拔尖个人项目) 2019

二、科研课题

1.国家自然科学青年基金  2018-2020

2.十三五传染病重大专项  2017-2020

3.首都卫生发展科研专项项目 2022-2024

4.NOVA创新计划 2023-2024

5.首都卫生发展科研专项项目 2022-2024

6.北京协和医院中央高水平医院临床科研专项 2022-2024


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研究成果

重要学术论文:

1.      Xinsheng Wu#, Guohui Wu#, Ping Ma#, Rugang Wang#, Linghua Li#, Yuanyi Chen, Junjie Xu, Yuwei Li, Quanmin Li, Yuecheng Yang, Lijing Wang, Xiaoli Xin, Ying Qiao, Gengfeng Fu*, Xiaojie Huang*, Bin Su*, Tong Zhang*, Hui Wang*, Huachun Zou*. Associations of modern initial antiretroviral therapy regimens with all-cause mortality in people living with HIV in resource-limited settings: a retrospective multicenter cohort study in China. Nature Communications. 2023 Sep 2;14(1):5334. doi: 10.1038/s41467-023-41051-w. (IF:16.6) [Q1]

2.      Xinsheng Wu#, Guohui Wu#, Ping Ma#, Rugang Wang#, Linghua Li#, Yinghui Sun, Junjie Xu, Yuwei Li, Tong Zhang, Quanmin Li, Yuecheng Yang, Lijing Wang, Xiaoli Xin, Ying Qiao, Bingxue Fang, Zhen Lu, Xinyi Zhou, Yuanyi Chen, Qi Liu, Gengfeng Fu, Hongxia Wei*, Xiaojie Huang*, Bin Su*, Hui Wang*, Huachun Zou*. Immediate and long-term outcomes after treat-all among people living with HIV in China: an interrupted time series analysis. Infectious diseases of poverty. 2023 Aug 14;12(1):73. doi: 10.1186/s40249-023-01119-7. (IF:8.1) [Q1]

3.      Wenjing Wang #, Shengnan Zhao #, Yaxin Wu #, Wenshan Duan, Sibo Li, Zhen Li, Caiping Guo, Wen Wang, Tong Zhang, Hao Wu, Xiaojie Huang*. Safety and Efficacy of Long-Acting Injectable Agents for HIV-1: Systematic Review and Meta-Analysis. JMIR Public Health Surveill. 2023 Jul 27;9:e46767. doi: 10.2196/46767. (IF:8.5) [Q1]

4.      Menglu Liu#, Hanying Qiu#, Wenyan Zhang, Tingting Mei, Shan Tang, Yuxue Gao, Yanqiu Zhu, Xiaojie Huang*, Haibin Yu*. Evaluation of blood-based PRO-C3 testing as a diagnostic marker for staging liver fibrosis: A systematic review and meta-analysis. J Gastroenterol Hepatol. 2023 Jul;38(7):1018-1027. doi: 10.1111/jgh.16240. (IF:4.369) [Q2]

5.      Zhen Li#*, Ping Yan#, Rui Wang, Xiaofan Lu, Yang Zhang, Bin Su, Xin Zhang, Lin Yuan, Zhiying Liu, Wei Jiang, Tong Zhang, Hao Wu*, Xiaojie Huang*. Persistent T cell proliferation and MDSCs expansion precede incomplete CD4+ T cell recovery in people with acute HIV-1 infection with early ART. Heliyon. 2023 Apr 18;9(5):e15590. doi: 10.1016/j.heliyon.2023.e15590. (IF:3.776) [Q2]

6.      Yang Zhao#, Juan Du#, Zhen Li, Yaxin Wu, Wenshan Duan, Wenjing Wang, Tong Zhang, Junjie Xu*, Hao Wu*, Xiaojie Huang*. It Is Time to Improve the Acceptance of COVID-19 Vaccines Among People with Chronic Diseases: A Systematic Review and Meta-analysis. J Med Virol. 2023 Feb;95(2):e28509. doi: 10.1002/jmv.28509. (IF: 20.693) [Q1]

7.      Chi Zhou#, Yaxin Wu#, Yang Zhang#, Yingying Wang, Hao Wu, Tong Zhang*, Guanzhi Chen*, Xiaojie Huang*. Factors Associated with Post-treatment Control of Viral Load in HIV-Infected Patients: A Systematic Review and Meta-analysis. Int J Infect Dis. 2023 Apr;129:216-227. doi: 10.1016/j.ijid.2023.01.025. (IF: 12.074) [Q1]

8.      Jiaojiao Liu#, Benedictor Alexander Nguchu#, Dan Liu, Yu Qi, Xire Aili, Shuai Han, Yuxun Gao, Xiaoxiao Wang, Hongwei Qiao, Chao Cai, Xiaojie Huang*, Hongjun Li*. Longitudinal white matter alterations in SIVmac239-infected rhesus monkeys with and without regular cART treatment. Front Immunol. 2023 Jan 12;13:1067795. doi: 10.3389/fimmu.2022.1067795. (IF: 8.786) [Q2]

9.      Xiangfei Xiu, Yuanyuan Qin, Yugang Bao, Yaokai Chen, Hao Wu, Xiaojie Huang*, Lu Wang*. The Practice and Potential Role of HIV Self-testing in China: Systematic Review and Meta-analysis. JMIR Public Health Surveill. 2022 Dec 2;8(12):e41125. doi: 10.2196/41125. (IF: 14.557) [Q1]

10.   Sisi Chen#, Feng Ren#, Ling Xu; Yao Gao, Xiangying Zhang, Yaling Cao,Zihao Fan, Yuan Tian, Xiaojie Huang*, Mei Liu*. Underestimated Prevalence of HIV, Hepatitis B Virus (HBV), and Hepatitis D Virus (HDV) Triple Infection Globally: Systematic Review and Meta-analysis. JMIR Public Health Surveill. 2022 Nov 29;8(11):e37016. doi: 10.2196/37016. (IF:14.557) [Q1]

11. XinshengWu#, GuohuiWu#, YanminMa#, XiaojieHuang#, YuechengYang#, YanshanCai#, GanfengLuo, PingMag, YingQiao, YuanyiChen, Yi-FanLin, YanxiaoGao, YueweiZhan, WeiSong, YingyingWang, RugangWang, XuejuanYang, LijunSun, HongxiaWei, QuanminLi, Xia, liXin, LijingWang, XichengWang, Ronghu, Xie, LijuanYang, XiaojunMeng, JinZhao*, LinghuaLi*, TongZhang*, JunjieXu*, GengfengFu*, HuachunZoua*. The impact of COVID-19 non-pharmaceutical interventions on HIV care continuum in China: an interrupted time series analysis. Lancet Regional Health-Western Pacific. 2022 Aug 10;29:100569. doi: 10.1016/j.lanwpc.2022.100569.(IF:8.559)[Q1]

12.   Yaxin Wu#, Yuening Zhang#, Yingying Wanga, Jiaqi Weia, b, Wenjing Wanga, Wenshan Duana, Yakun Tiana, Meixin Rena, Zhen Lia, b, Wen Wanga, Tong Zhanga, Hao Wua, Xiaojie Huang*. Bedaquiline and Linezolid improve anti-TB treatment outcome in drug-resistant TB patients with HIV: A systematic review and meta-analysis. Pharmacol Res. 2022 Aug;182:106336. doi: 10.1016/j.phrs.2022.106336. (IF:10.334) [Q1]

13.   Kui-Fang Du#, Xiao-Jie Huang#, Chao Chen, Wen-Jun Kong, Lian-Yong Xie, Hong-Wei Dong* and Wen-Bin Wei *. Macular Changes Observed on Optical Coherence Tomography Angiography in Patients Infected with Human Immunodeficiency Virus Without Infectious Retinopathy. Front Med (Lausanne). 2022 Apr 7; 9:820370. doi: 10.3389/fmed.2022.820370. (IF:5.058) [Q2]

14.   Yan Yu, Xinyu Wang, Yaxin Wu, Wenjia Weng, Ming Zhang, Juan Li, Xiaojie Huang*, Yanqing Gao*. The benefits of psychosocial interventions for mental health in men who have sex with men living with HIV: a systematic review and meta-analysis. BMC Psychiatry. 2022 Jun 29;22(1):440. doi: 10.1186/s12888-022-04072-1. (IF:4.144) [Q2]

15.   Hongyi Wang#, Zixin Wang#, Xiaojie Huang#, Yaokai Chen, Hui Wang, Sitong Cui, Jing Zhang, Zhenxing Chu, Qinghai Hu, Haibo Ding, Hanzhu Qian, Huachun Zou, Weiming Tang, Yangyang Gao, Xia Jin, Zhaozhen Liu, Lukun Zhang, Jin Zhao, Xiaoqing He, Yongjun Jiang, Wenqing Geng, Junjie Xu*, Hong Shang*; for the China Real-World Oral Intake of PrEP (CROPrEP) Study Team. Association of HIV preexposure prophylaxis use with HIV incidence among men who have sex with men in China: a nonrandomized controlled trial. JAMA Network Open. 2022 Feb 1;5(2):e2148782. doi: 10.1001/jamanetworkopen.2021.48782. (IF:13.353) [Q1]

16.   Ke Zhang#, Yang Zhang#, Jing Zhou, Lulu Xu, Chi Zhou, Guanzhi Chen*, Xiaojie Huang*. Comparison of the Efficacy and Safety of a Doravirine-Based, Three-Drug Regimen in Treatment-Naïve HIV-1 Positive Adults: A Bayesian Network Meta-Analysis. Front Pharmacol. 2022 Apr 20;13: 676831. doi: 10.3389/fphar.2022.676831. (IF:5.988) [Q1]

17.   Xiaoyan Bi#, Fan Liu#, Xiangjun Zhang, Hongyi Wang, Zehao Ye, Ke Yun, Xiaojie Huang#, Haibo Ding, Wenqing Geng, and Junjie Xu*. Vitamin D and calcium supplementation reverses Tenofovir-caused bone mineral density loss in populations attending ART or PrEP: a systematic review and meta-analysis. Front Nutr. 2022 Mar 31;9: 749948. doi: 10.3389/fnut.2022.749948. (IF:6.59) [Q1]

18.   Zhuang Tao#, Chong Ma, Jipeng Dong, Huijun Guo, Xin Li, Xinghua Tan, Yuqi Yang, Jianping Ma, Shuiqing Liu, Jian Wang∗, Xiaojie Huang∗. The Immunomodulatory Effects of Artesunate on Immunological Non-responders in Long-term ART-treated People Living with HIV in Selected Provinces in China: A Non-randomized Concurrent Control Trial. Pharmacological Research-Modern Chinese Medicine, 2022 Jun; 3: 100067. doi.org/10.1016/j.prmcm.2022.100067. (IF: 3.829) [Q1]

19.   Xiaojie Huang #, Ying Yan #, Bin Su #, Dong Xiao#, Maohe Yu, Xia Jin, Junyi Duan, Xiangjun Zhang, Shimin Zheng, Yuan Fang, Tong Zhang, Weiming Tang *, Lunan Wang *, Zixin Wang * and Junjie Xu*. Comparing Immune Responses to Inactivated Vaccines against SARS-CoV-2 between People Living with HIV and HIV-Negative Individuals: A Cross-Sectional Study in China. Viruses. 2022 Jan 28;14(2):277. doi: 10.3390/v14020277. (IF:5.818) [Q2]

20.   Xinyu Wang#, Ming Zhang#, Yu Chen. Yirong Liu, Yan Yu, Xiaojie Huang*. Yanqing Gao*. Risk for Hepatitis B Virus Reactivation in Patients with Psoriasis Treated with Biological Agents: A Systematic Review and Meta-Analysis. Dermatol Ther (Heidelb). 2022 Mar;12(3):655-670. doi: 10.1007/s13555-022-00682-5. (IF:3.858) [Q2]

21.   Yakun Tian#, Wei Hua#, Yaxin Wu#, Tong Zhang, Wen Wang, Hao, Wu, Caiping Guo*, Xiaojie Huang*. Immune response to hepatitis B virus vaccine among people living with HIV: a meta-analysis. Front Immunol, 2021 Dec 22;12: 745541. doi: 10.3389/fimmu.2021.745541 (IF:8.786) [Q1]

22.   Xiaojing Lian#, Lili Zhang#, Yang Zhao#, Yuhua Li, Xuemin Jing, Xin Liu, Jianing Han, Jianhong Ma, Yongyong Zhang, Huimin Guo*, Xiaojie Huang*. Utilization of a mobile multifunctional workstation for coronavirus nasopharyngeal/oropharyngeal specimen collection. Front Public Health, 2021 Jan 24;9:794359. doi: 10.3389/fpubh.2021.794359. eCollection 2021. (IF:6.461) [Q1]

23.   Ying Guo#, Xiaojie Huang#, Xintong Sun, Yixi Yu, Yan Wang, Baojin Zhang, Jie Cao, Shuo Wen, Yuchen Li, Xin Wang, Siyu Cai, Wei Xia, Feili Wei, Junyi Duan, Haozhi Dong, Shan Guo, Fengqiu Zhang*, Dongxiang Zheng* and Zheng Sun*. The underrated salivary virome of men who have sex with men infected with HIV. Front Immunol, 2021 Dec 2;12: 759253. doi: 10.3389/fimmu.2021.759253 (IF:8.786) [Q1]

24.   Zhuang Tao, Xiao-Jie Huang*, Ying Liu, Ru Wang, Ji-Peng Dong, Bi-Yan Liang, Wen Zou, Guo-Jian Gao, Zhuo Wang, Ke Zhang, Hao Wu, Tong Zhang, Jian Wang*. Efficacy of integrated Traditional Chinese Medicine and anti-retroviral therapy on immunological nonresponse in patients with human immunodeficiency virus/acquired immunodeficiency syndrome: a Meta-analysis of randomized controlled trial. J Tradit Chin Med. 2021 Oct;41(5):669-676. doi: 10.19852/j.cnki.jtcm.2021.05.002. (IF: 2.547) [Q3]

25.   Huan Xia#, Xiao-Jie Huang#, Yue Hu, Li-Ying Gao, Yue Wu, Hao Wu, Zhong-Fang Yan, Ping Ma*. Switching from efavirenz to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide reduces central nervous system symptoms in people living with human immunodeficiency virus. Chin Med J (Engl). 2021 Oct 13. doi:10.1097/CM9.0000000000001824. (IF:6.133) [Q1]

26.   Chunxiang Guo#, Yaxin Wu#, Yang Zhang, Xinchao Liu, Aixin LI, Meixia Gao, Tong Zhang, Hao Wu, Guanzhi Chen*, Xiaojie Huang *. Transmitted drug resistance in ART-naive persons with acute/ early/ primary HIV infection: a systematic review and meta-analysis. Frontiers in Pharmacology. 2021 Nov 24;12: 718763. doi: 10.3389/fphar.2021.718763 (IF:5.988) [Q1]

27.   Xiaojie Huang#, Maohe Yu#, Gengfeng Fu#, Guanghua Lan#, Linghua Li#, Jianzhou# Yang, Ying Qiao#, Jin Zhao#, Han-Zhu Qian, Xiangjun Zhang, Xinchao Liu, Xia Jin,Guohong Chen, Hui Jiang, Weiming Tang*, Zixin Wang*, Junjie Xu*. Willingness to receive COVID-19 vaccination among people living with HIV and AIDS in China: A nationwide cross-sectional online survey. JMIR Public Health Surveill. 2021 Oct 21;7(10): e31125. doi: 10.2196/31125. (IF:14.557) [Q1]

28.   Ni Wang, Muyu Wang, Xin Xin, Tong Zhang, Hao Wu, Xiaojie Huang* and Honglei Liu*. Exploring the Relationship between Anxiety, Depression, and Sleep Disturbance among HIV Patients in China from a Network Perspective. Front Psychiatry. 2021 Oct 22;12: 764246.doi: 10.3389/fpsyt.2021.764246. (IF:5.435) [Q2]

29.   Yingying Wang#, Xiaojie Huang#, Yaxin Wu, Aixin Li, Yakun Tian, Meixin Ren, Zhen Li,Tong Zhang, Hao Wu and Wen Wang*. Increased Risk of Vitamin D Defificiency Among HIV-Infected Individuals: A Systematic Review and Meta-Analysis. Front Nutr. 2021 Aug 18;8: 722032. doi: 10.3389/fnut.2021.722032. (IF:6.59) [Q1]

30.   Ke Zhang, Yang Zhang, Xincao Liu, Ainxin Li, Meixia Gao, Jianhua Hou, Chunxiang Guo, Tong Zhang, Hao Wu, Xiaojie Huang*, Guanzhi Chen*. Three-drug regimens containing integrase inhibitor show good efficacy and safety in treatment-naive patients with HIV-1: a Bayesian analysis. Front Pharmacol. 2021 Jul 21;12: 603068. doi: 10.3389/fphar.2021.603068. (IF:5.988) [Q1]

31.   Jing Zhang#, Xiao-jie Huang#, Wei-ming Tang#, Zhen-xing Chu#, Qing-hai Hu, Jing Liu, Haibo Ding, Xiao-xu Han, Zi-ning Zhang, Yong-jun Jiang, Wen-qing Geng, Wei Xia , Jun-jie Xu* and Hong Shang*. Rapid Clinical Progression and Its Correlates Men in China with Acute HIV Who Have Sex With Men: Findings From a 5-Year Multicenter Prospective Cohort Study. Front Immunol. 2021 Jul 22;12: 712802. doi: 10.3389/fimmu.2021.712802. (IF:8.786) [Q1]

32.   Yang Zhao, Xiaoli Xin, Huiwen Deng, Junjie Xu, Wenjia Weng, Ming Zhang, Juan Li, Yanqing Gao, Xiaojie Huang*, Cuie Liu*. Improving the acceptability of human papillomavirus vaccines among men who have sex with men according to the correlated factors: a systematic review and meta-analysis. Front Pharmacol. 2021 Mar 24;12: 600273. doi: 10.3389/fphar.2021.600273. (IF: 5.81) [Q1]

33.   Guo, Y#, Xia, W, Wei, F, Feng, W, Duan, J, Sun, X, Yu, Y, Wang, Y, Zhang, B, Cao, J, Li, W, Dong, H, Guo, S, Zhang, F*, Huang, X* & Sun, Z*. Salivary microbial diversity at different stages of human immunodeficiency virus infection. Microb Pathog. 2021 Jun;155: 104913. doi: 10.1016/j.micpath.2021.104913. (IF:3.847) [Q3]

34.   Hu X#, Huang X#, Hou J, Ding L, Su C, Meng F*. Diagnostic accuracy of spleen stiffness to evaluate portal hypertension and esophageal varices in chronic liver disease: a systematic review and meta-analysis. Eur Radiol. 2021 Apr;31(4):2392-2404. doi: 10.1007/s00330-020-07223-8. (IF=4.101) [Q1]

35.   Xia, H. #, Gao, L. #, Gong, X., Zaongo, S. D., Zhang, T., Wu, H., Ma, P. * & Huang, X*. The Challenge of Potential Drug–Drug Interactions Among People Living With HIV on Antiretroviral Therapy: A Cross-Sectional Study in Selected Provinces in China. Frontiers in Pharmacology. 2020, May 27;11:800. doi: 10.3389/fphar.2020.00800. eCollection 2020. (IF:4.225) [Q1]

36.   Li, Y. #, Huang, X. #, Chen, H., Qin, Y., Hou, J., Li, A., Wu,H. , Yang, X.& Chen, Y*. The prevalence of cryptococcal antigen (CrAg) and benefits of pre-emptive antifungal treatment among HIV-infected persons with CD4+ T-cell counts< 200 cells/μL: evidence based on a meta-analysis. BMC Infectious Diseases. 2020 Jun 12;20(1):410. doi: 10.1186/s12879-020-05126-z. (IF:2.688) [Q3]

37.   Qin, Y. #, Huang, X. #, Chen, H., Liu, X.Li, Y., Hou, J., Li, A., Yan, X, Chen, Y*. Burden of Talaromyces marneffei infection in people living with HIV/AIDS in Asia during ART era:a systematic review and meta-analysis. BMC Infectious Diseases. 2020 Jul 29;20(1):551. doi: 10.1186/s12879-020-05260-8. (IF:2.688) [Q3]

38.   Yuan Gao #, Qi Li #, Hongbo Shi #, Yingmei Feng, Tong Zhang, Yu Chen, Lianchun Liang, Dexi Chen, Hao Wu, Ronghua Jin, Xiaojie Huang *. Preliminary Exploration of the Cause of Liver Disorders During Early Stages in COVID-19 Patients. Frontiers in Medicine. 2020 Aug 7;7:501. doi: 10.3389/fmed.2020.00501. (IF:3.9) [Q2]

39.   Xu JJ#, Huang XJ#, Liu XC, Wang LM, Chen YK, Wang H, Zhang FJ, Wu H, Li TS, Han MJ, Zhao F, Ding HB, Duan JY, Sheng GS, Shang H*. Consensus statement on human immunodeficiency virus pre-exposure prophylaxis in China. Chin Med J (Engl). 2020 Dec 5;133(23):2840-2846. doi: 10.1097/CM9.0000000000001181. (IF=1.555) [Q1]

40.   Huang X#, Xu L#, Sun L, Gao G, Cai W, Liu Y, Ding H, Wei H, Ma P, Wang M, Liu S, Chen Y, Chen X, Zhao Q, Yu J, Song Y, Chen H, Wu H, Qin S*, Li L*. Six-year Immunologic Recovery and Virological Suppression of LPV/r-based Second-line Antiretroviral among HIV Patients: A Multi-center Real-world Cohort Study in China. Frontiers in Pharmacology. 2019 Dec 11;10:1455. doi: 10.3389/fphar.2019.01455. (IF:3.845) [Q1]

41.   Huang Y#, Huang X#, Chen H, Wu H*, Chen Y*. Efficacy and safety of raltegravir based dual therapy in AIDS patients: a meta-analysis from randomized controlled trials. Frontiers in Pharmacology. 2019 Oct 17;10:1225. doi: 10.3389/fphar.2019.01225. (IF:3.845) [Q1]

42.   Zhang Y, Hou J, Shi P, Chang S, Wu A, Song A, Wu H, Huang X*, Shi J*. Problem-based learning could tackle the issue of insufficient education and adherence in people living with HIV/AIDS[J]. Frontiers in pharmacology. 2019 Aug 21;10:901. doi: 10.3389/fphar.2019.00901. (IF:3.845) [Q1]

43.   Zhiyuan Yang#, Xiaojie Huang#, Xinchao Liu, Jianhua Hou, Wenfang Wu,Aixin Song, Kathrine Meyers, Tong Zhang, Hui Chen*, Hao Wu*. Psychometric Properties and Factor Structure of the Chinese Version of the Hospital Anxiety and Depression Scale in People Living With HIV. Frontiers in Psychiatry. 2019 May 16;10:346. doi: 10.3389/fpsyt.2019.00346. (IF:2.875) [Q2]

44.   Hu X#, Huang X#, Chen H, Zhang T, Hou J, Song A, Ding L, Liu W, Wu H*, Meng F*. Diagnostic effect of shear wave elastography imaging for differentiation of malignant liver lesions: a meta-analysis. BMC gastroenterology. 2019 Apr 25;19(1):60. doi: 10.1186/s12876-019-0976-2. (IF:2.252) [Q4]

45.   Xiaojie Huang #, Xinchao Liu #, Jieqing Chen #, Yugang Bao, Hou Jianhua, Lu Xiaofan, Xia Wei, Xia Huan, Song Aixin, Liu Zhiying, Su Bin, Chen Hui*, Chen Yaokai*, Wu Hao*. Evaluation of Blood-Based Antibody Rapid Testing for HIV Early Therapy: A Meta-Analysis of the Evidence. Frontiers in Immunology. 2018 Jun 26;9:1458. doi: 10.3389/fimmu.2018.01458.(IF:5.511)[Q1]

46.   Yinqiu Huang#, Xiaojie Huang#, Yadong Luo, Yihong Zhou, Xingbao Tao, Hui Chen, Aixin Song, Yaokai Chen *, Hao Wu *. Assessing the Efficacy of Lopinavir/Ritonavir-Based Preferred and Alternative Second-Line Regimens in HIV-Infected Patients: A Meta-Analysis of Key Evidence to Support WHO Recommendations. Frontiers in pharmacology. 2018 Aug 14;9:890. doi: 10.3389/fphar.2018.00890. (IF:3.831) [Q1]

47.   Xiaojie Huang#, Jianhua Hou#, Aixin Song, Xinchao Liu, Xiaodong Yang, Junjie Xu, Jing Zhang, Qinghai Hu, Hui Chen, Yaokai Chen, Kathrine Meyers *, Hao Wu *. Efficacy and safety of oral TDF-based pre-exposure prophylaxis for men who have sex with men: A systematic review and meta-analysis. Frontiers in pharmacology. 2018 Sep 4;9:799. doi: 10.3389/fphar.2018.00799.(IF:3.831)[Q1]

48.   Xiaojie Huang #, Kathrine Meyers #, Xinchao Liu #, Xia Li, Tong Zhang, Wei Xia, Jiahua Hou, Aixin Song, Haolan He, Chongxi Li, Shenghua He, Weiping Cai, Huolin Zhong, Chengyu Huang, Shuiqing Liu, Hui Wang, Xuemei Ling, Ping Ma, Rongxia Ye, Gang Xiao, Taisheng Li, Ding Ding, Kristine Yaffe, Hui Chen *, Yaokai Chen *, Hao Wu *. The Double Burdens of Mental Health Among AIDS Patients with Fully Successful Immune Restoration: A Cross-Sectional Study of Anxiety and Depression in China. Frontiers in Psychiatry. 2018 Aug 24;9:384. doi: 10.3389/fpsyt.2018.00384. (IF: 2.875) [Q2]

49.   Aixin Song #, Xinchao Liu #, Xiaojie Huang #, Kathrine Meyers, Djin Ye Oh, Jianhua Hou, Wei Xia, Bin Su, Ni Wang, Xiaofan Lu, Huan Xia, Xiaodong Yang, Hui Chen *, Hao Wu *. From CD4-Based Initiation to Treating All HIV-Infected Adults Immediately: An Evidence-Based Meta-analysis. Frontiers in Immunology. 2018 Feb 13;9:212. doi: 10.3389/fimmu.2018.00212. (IF: 6.429) [Q1]

50.   Xiaojie Huang#, Huiqin Li#, Kathrine Meyers #, Wei Xia, Zhihao Meng, Chongxi Li, Jinsong Bai, Shenghua He, Weiping Cai, Chengyu Huang, Shuiqing Liu, Hui Wang Xuemei Ling, Ping Ma, Daling Tan, Fuxiang Wang, Lianguo Ruan, Hongxin Zhao, HongxiaWei, Yanfen Liu, Jianhua Yu, Hongzhou Lu, Min Wang, Tong Zhang, Hui Chen*, Hao Wu*. Burden of sleep disturbances and associated risk factors: A crosssectional survey among HIV infected persons on antiretroviral therapy across China. Scientific Reports. 2017 Jun 16;7(1):3657. doi: 10.1038/s41598-017-03968-3. (IF: 4.259) [Q2]

51.   Xiaojie Huang#, Xinchao Liu #, Kathrine Meyers #, Lihong Liu, Bin Su, Pengfei Wang, Zhen Li, Lan Li, Tong Zhang, Ning Li, Hui Chen*, Haiying Li*, Hao Wu*. Cytokine cascade and networks among MSM HIV seroconverters: implications for early immunotherapy. Scientific Reports. 2016 Nov 10;6:36234. doi: 10.1038/srep36234. (IF: 5.228) [Q2]

52.   Xiaofan Lu #, Bin Su #, Huan Xia, Xin Zhang, Zhiying Liu, Yunxia Ji, Zixuan Yang, Lili Dai, Luzia M. Mayr, Christiane Moog, Hao Wu, Xiaojie Huang* and Tong Zhang*. Low Double-Negative CD3+CD4−CD8− T Cells Are Associated with Incomplete Restoration of CD4+ T Cells and Higher Immune Activation in HIV-1 Immunological Non-Responders. Front Immunol. 2016 Dec 9;7:579. doi: 10.3389/fimmu.2016.00579. (IF: 5.695) [Q1]

53.   Xiaojie Huang #, Yuanlong Xu#, Qiuying Yang, Jieqing Chen, Tong Zhang, ZaiCun Li, Caiping Guo, Hui Chen*, Hao Wu*, Ning Li*. Efficacy and biological safety of lopinavir/ritonavir based anti-retroviral therapy in HIV-1-infected patients: a meta-analysis of randomized controlled trials. Scientific Reports. 2015 Feb 23;5:8528. doi: 10.1038/srep08528. (IF: 5.578) [Q2]

54.   Zhongwei Jia #, Xiaojie Huang #, Hao Wu* #, Tong Zhang #, Ning Li, Peipei Ding,Yixuan Sun, Zhiying Liu, Feili Wei, Hongwei Zhang, Yanmei Jiao, Yunxia Ji, Yonghong Zhang, Caiping Guo, Wei Li, Danlei Mou, Wei Xia, Zhen Li, Dexi Chen, Huiping Yan, Xinyue Chen, Jinkou Zhao, Kathrine Meyers, Ted Cohen, Kenneth Mayer, Joshua A Salomon, Zuhong Lu *, Christopher Dye*. HIV burden in men who have sex with men: a prospective cohort study 2007–2012. Scientific Reports. 2015 Jul 2;5:11205. doi: 10.1038/srep11205. (IF: 5.578) [Q2]

55.   Xiaojie Huang, Sara Lodi , Zoe Fox,Wei Li, Andrew Phillips, Kholoud Porter, Irja Lutsar, Anthony Kelleher, Ning Li,  Xiaoning Xu , Hao Wu* and Anne M Johnson. Beijing PRIMO cohort studyCASCADE Collaboration in EuroCoord. Rate of CD4 decline and HIV-RNA change following HIV Seroconversion in men who have sex with men: a comparison between the Beijing PRIMO and CASCADE cohorts. JAIDS. 2013 Apr 1;62(4):441-6. doi: 10.1097/QAI.0b013e31827f5c9a. (IF: 4.653) [Q3]

56.   Chen J#, Li W#, Huang X#, Guo C#, Zou R, Yang Q, Zhang H, Zhang T, Chen H*, Wu H*. Evaluating Total Lymphocyte Count as a Surrogate Marker for CD4 Cell Count in the Management of HIV-Infected Patients in Resource-Limited Settings: A Study from China. PLoS ONE. 2013 Jul 18;8(7):e69704. doi: 10.1371/journal.pone.0069704. (IF:3.73) [Q2]

57.   Xiaojie Huang, Hui Chen, Wei Li, Haiying Li, Xia Jin, Alan S. Perelson, Zoe Fox, Tong Zhang, Xiaoning Xu, Hao Wu*. Precise determination of time to reach viral load set point after acute HIV-1 infection. JAIDS. 2012 Dec 1;61(4):448-54. doi: 10.1097/QAI.0b013e31827146e0. (IF:4.653) [Q3]

58.   Chao Wang#, YouXin Wang#, XiaoJie Huang#, Xia Li , YouXin Wang , Tong Zhang , ManShu Song *, LiJuan Wu , Juan Du , XiaoQin Lu , Shuang Shao , FeiFei Zhao , Michele A. Ball, Hao Wu*, Wei Wang*. Prevalence and Factors Associated with  ADDIN NE.Ref.{8D305615-A092-4CF3-8EA9-4462906BCA6E}Hepatitis B Immunization and Infection among Men Who Have Sex with Men in Beijing, China. Plos One. 2012;7(10):e48219. doi: 10.1371/journal.pone.0048219. (IF:4.092) [Q2]

59.   Wei Li#, Xiaojie Huang#, Hongfei Tong, Yuxuan Wang, Tong Zhang, Wen Wang, LiliDai ,Tongzeng Li, Shengzhang Lin* ,Hao Wu*. Comparison of the regulation of β-catenin signaling by type I, type II and type III interferons in hepatocellular carcinoma cells. Plos One. 2012;7(10):e47040. doi: 10.1371/journal.pone.0047040. (IF: 4.092) [Q2]

60.   Wei Li#, Xiaojie Huang#, Zhuoming Liu, Yuxuan Wang, Hongwei Zhang, Hongfei Tong, Hao Wu*, Shengzhang Lin*. Type III interferon induces apoptosis in human lung cancer cells. ONCOLOGY REPORTS. 2012 Sep;28(3):1117-25. doi: 10.3892/or.2012.1901. (IF:1.835) [Q3]

61.   Xiao-jie Huang, Hai-ying Li, De-xi Chen, Xi-cheng Wang, Zai-cun Li, Ya-song Wu, Tong Zhang, Yan-qing Gao*, Hao Wu*. Clinical Analysis of Skin Lesions in 796 Chinese HIV-positive Patients. Acta Derm Venereol. 2011 Sep;91(5):552-6. doi: 10.2340/00015555-1107. (IF:2.94) [Q2]

62.   Haiying Li#, Xiaojie Huang# , Caiping Guo, Wen Wang, Zaicun Li, Tong Zhang, Qiaoli Peng, Xinyue Chen, Hao Wu*. Heightened T-cell proliferation without an elevation of CD4+ T cell spontaneous apoptosis in AIDS patients. Clinical Immunology. 2008 Dec;129(3):499-508. doi: 10.1016/j.clim.2008.08.004. (IF: 3.93) [Q1]

 

重要奖项:

1.HIV/HCV共感染及HIV单独感染者临床特点及发病机制研究与应用 北京市科学技术进步奖 二等奖 202008

2.我国男男性接触(MSM)人群HlV-1新发感染及疾病进展模式研究 首都十大疾病科技攻关 创新型科技成果 201311

3.艾滋病队列干预及致病机制研究 首都十大疾病重大科技成果 创新型科技成果 201303


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学校介绍


  首都医科大学建校于1960年,是北京市重点高等院校,著名泌尿外科专家、中国科学院院士、中国工程院院士、原全国人大常委会副委员长吴阶平教授为首任院长。学校由校本部和附属医院(即临床医学院)组成。校本部设有基础医学院、生物医学工程学院、公共卫生与家庭医学学院、高等职业教育学院、中医药学院、顺义校区、继续教育学院、护理学院、卫生事业管理与发展学院及首都医科大学国际教学部;附属医院包括宣武医院(第一临床医学院)、附属北京友谊医院(第二临床医学院)、附属北京朝阳医院(第三临床医学院)、附属北京同仁医院(第四临床医学院)、附属北京天坛医院(第五临床医学院)、附属北京安贞医院(第六临床医学院)、附属北京口腔医院(口腔医学院)、附属北京儿童医院(儿科医学院)、附属北京妇产医院(妇产医学院)、附属北京安定医院(精神卫生学院)、附属复兴医院(第八临床医学院)、附属北京中医医院(中医药临床医学院)和康复医学院。

  学校和附属医院现有教职员工和医护人员22575人。有院士4人,正高职称700余人,副高职称1800余人。学校学科专业齐全,学科力量雄厚,在基础和临床各专业拥有一大批具有很高造诣的专家学者,现有3个国家级重点学科,有38个博士学位授予权学科,58个硕士学位授予权学科和2个博士后科研流动站。

  校本部和附属医院总占地面积97.3万平方米,总建筑面积134万平方米 ,固定资产总值近46.5亿元,图书馆藏书108.3万册 ,住院病床10039张。学校开办的七年制专业中设有临床医学和口腔医学;五年制专业中设有临床医学、口腔医学、预防医学、护理学、中医学等;四年制专业中设有生物医学工程、中药学和康复治疗学。在临床医学专业中设有儿科医学、康复医学、医学影像、精神卫生与精神病学和医学检验5个专业方向;在生物医学工程专业中设有医学影像设备与技术和听力学专业方向。高等职业教育设有护理、医学检验、药学、医学影像技术、康复技术、口腔修复工艺、眼科验光、实验动物技术、中医学、中药制剂、医学信息、临床医学、预防医学、中药经营贸易和中医学美容专业方向15个专业。首都医科大学现已成为以培养高层次本科生与研究生为核心、以临床应用型人才为主和培养预防、康复、生物医学工程和医学基础各学科、各层次人才,位于全国先进医学院校行列的高等学府。

  学校具有较强的学术发展与科研实力,在校本部和附属医院建有一批国家级和市级重点学科和重点实验室,建有高水平的国家级或市级研究和培训机构,如卫生部全科医学培训中心、临床医学研究所、基础医学研究所、神经科学研究所、眼科研究所、老年病医疗研究中心、泌尿外科研究所、心肺血管医疗研究中心、生命科学院、卫生毒理检测中心、生物工程技术研究中心、祖国医学研究所、临床疾病研究中心、中医肝病临床研究中心、生殖医学研究所、心血管疾病临床试验及社区干预中心和北京市卫生政策与卫生经济研究中心等。神经生物学、细胞生物学、电生理学、基础免疫学、实验寄生虫学、医学图像处理、生物医学、信息检测与处理、神经内科、神经外科、心脏内外科、肾移植、呼吸和消化内科、口腔颌面外科、眼科、耳鼻咽喉科、小儿血液病等领域在国内外享有较高声誉,很多学科的研究和医疗水平已经达到或接近国际先进水平。

  学校十分重视对外交流与合作,改革开放以来,先后与世界20多个国家和地区签定了友好交流协议, 近十年中,先后接待美国、加拿大、英国、澳大利亚、法国、瑞典、日本、荷兰、意大利、德国、丹麦及台湾、香港和澳门等50多个国家和地区的专家学者8000余人次来校进行学术交流和参观访问。同时,学校积极选送教师、科研人员和管理干部出国进修、参加学术会议和考察访问。

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