近5年发表文章：

1. Wang G§,Huang M§, Jin H§,Jia J,Dong L,Wang F,Xue Y,Deng Y*, Jiang G*, Huang H*. The practical value of Xpert MTB/RIF Ultra for diagnosis of pulmonary tuberculosis in a high tuberculosis burden setting: a prospective multicenter diagnostic accuracy study. Microbiology Spectrum,2022,;e0094922

2. Yu X§,Zhang T§,Kong Y§,Wang F,Dong L,Han M*,Huang H* Xpert MTB/RIF Ultra outperformed the Xpert assay in tuberculosis lymphadenitis diagnosis: a prospective head-to-head cohort study. International Journal of Infectious Diseases,2022,122:741-6

3. Rui Zhu§, Xia Yu§, Tingting Zhang, Yaoyao Kong, Fen Wang,Junnan Jia, Yi Xue, and Hairong Huang*. In Vitro and Intracellular Inhibitory Activities of Nosiheptide Against Mycobacterium Abscessus. Front Microbiol. 2022

4. Chen S§, Wang F§, Xue Y, Huo F, Jia J, Dong L, Zhao L, Jiang G*, Huang H*. Doubled Nontuberculous Mycobacteria Isolation as a Consequence of Changes in the Diagnosis Algorithm. Infect Drug Resist. 2022,15:3347-3355

5.   Wang G§, Liang R§, Sun Q, Liao X, Wang C, Huang H*.Extremely high levels of central nervous system involvement in miliary tuberculosis. BMC Infectious Diseases，2022, 22(1):417

6. Tingting Zhang§, Xia Yu§, Shu'an Wen, Yi Xue, Hua Xiao, Ruyan Ren, Fen Wang, Lingling Dong, Shibing Qin*, Hairong Huang*. Bone penetration of cycloserine in osteoarticular tuberculosis patients of China. Antimicrob Agents Chemother.

7. Wei-wei Jiao§, Gui-rong Wang§, Lin Sun, Jing Xiao, Jie-qiong Li, Yacui Wang, Shu-Ting Quan, Hai-rong Huang*,A-dong Shen*. Multiple cross displacement amplification combined with Real-time PCR platform: a rapid, sensitive method to detect Mycobacterium tuberculosis. Frontiers in Microbiology,2022 

8. Du J, Li Q, Liu M, Wang Y, Xue Z, Huo F, Zhang X, Shang Y, Li S, Huang H, Pang Y. Distinguishing Relapse From Reinfection With Whole-Genome Sequencing in Recurrent Pulmonary Tuberculosis: A Retrospective Cohort Study in Beijing, China.Front Microbiol. 2021, 12:754352. doi: 10.3389/fmicb.2021.754352. eCollection 2021.PMID: 34956119 

9. Yu X,Huo F,Wang F,Wen S,Jiang G,Xue Y,Dong L,Zhao L,Zhu R, Hairong Huang*. In Vitro antimicrobial activity comparison of linezolid, tedizolid, sutezolid and delpazolid against slowly growing Mycobacteria isolated in Beijing, China. Infection and Drug Resistance,2021 

10. Zhuman Zhang§, Jian Du§,Tao Liu§, Feng Wang, Junnan Jia, Lingling Dong, Liping Zhao,Yi Xue, Guanglu Jiang, Xia Yu*, Hairong Huang*.EasyNAT MTC Assay: A Simple, Rapid, and Low Cost Cross-Priming Amplification Method for Detection of Mycobacterium Tuberculosis Suitable for Point-of-Care Testing. Emerging Microbes & Infections.doi：10.1080/22221751.2021.1959271

11. Wen S§, Gao X§,Zhao W§, Huo F, Jiang G,DongL, Zhao L,Wang F,Yu X*,Huang H*. Comparison of the in vitro activity of linezolid, tedizolid, sutezolid, and delpazolid against rapidly growing mycobacteria isolated in Beijing, China. Int J Infect Dis. 2021;109:253-260. doi: 10.1016/j.ijid.2021.06.055. 

12. Jun Fan§, Tinglong Lan§, Kai Tang§, Guirong Wang§, Weijie Dong, Dawei Li, Guangxuan Yan,Yuan Li, Guohua Lei, Jianlin Shan, Qinglei Wang, Jianhua Ma, Hairong Huang*, Shibing Qin*.The comparative influence of 2 and 4 week preoperative anti-tuberculosis treatment on spinal tuberculosis surgery: a multicenter, prospective randomized clinical trial. Infectious Diseases and Therapy.2021. doi: 10.1007/s40121-021-00462-2. 

13. Guan Liu§, Xia Yu§，JingjingLuo, Yanjie Hu,Lingling Dong, Guanglu Jiang, FengminHuo,Fen Wang,Qian Liang, Hairong Huang* .Mycobacterium vicinigordonae sp.nov.,a slow growing scotochromogenic species isolated from sputum. International Journal of Systematic and Evolutionary Microbiology.2021,71(5). doi: 10.1099/ijsem.0.004796 

14. Shan Gao§, Chong Wang§, Xia Yu§, Tianlu Teng, Yuanyuan Shang, Junnan Jia, Lingling Dong,Liping Zhao, Shuku Liu*, Naihui Chu*, Hairong Huang*.Xpert MTB/RIF Ultra enhances tuberculous pleurisy diagnosis for patients with unexplained exudative pleural effusion who underwent a pleural biopsy via VATS: a prospective cohort study. International Journal of Infectious Diseases.2021 106:370-375. doi: 10.1016/j.ijid.2021.04.011. 

15. Suting Chen#, Tianlu Teng#, Zhuman Zhang, Yuanyuan Shang, Hua Xiao, Guanglu Jiang, Fen Wang, Junnan Jia1, Lingling Dong, Liping Zhao, Naihui Chu*, Hairong Huang*.Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) exhibits direct antibacterial activity against Mycobacterium abscessus. Infection and Drug Resistance,2021;14:1199-1208. doi: 10.2147/IDR.S303113. eCollection 2021

16. Sun Q#, Wang S, Liao X, Jiang G, Huang H*, Li H*, Wang G*. Fidaxomicin has high in vitro activity against Mycobacterium tuberculosis. J Med Microbiol. 2021, 70(3). doi: 10.1099/jmm.0.001324.

17. Guirong Wang#, Guanglu Jiang#, Wei Jing, Zaojing Zong, Xia Yu, Suting Chen, Weimin Li, Hairong Huang*. Prevalence and molecular characterizations of seven additional drug resistance among multidrug-resistant tuberculosis in China: A subsequent study of a national survey. J Infect. 2021, 82(3):371-377. doi: 10.1016/j.jinf.2021.02.004.(IF:4.972)

18. Huang M#, Wang G#, Sun Q, Jiang G, Li W, Ding Z, Jia H, Gao M, Huang H*, Li Q*. Diagnostic accuracy of Xpert MTB/RIF Ultra for tuberculous meningitis in a clinical practice setting of China.Diagn Microbiol Infect Dis. 2021 Jan 6;100(1):115306. doi: 10.1016/j.diagmicrobio.2020.115306.

19. Gong Z#,Wang G#,Zeng J,Stojkoska A,Huang H*,Xie J*. Differential DNA Methylomes of clinical MDR, XDR and XXDR Mycobacterium tuberculosis isolates revealed by Using Single-Molecule Real-Time Sequencing. Journal of Drug Targeting.2021, 29(1):69-77. doi: 10.1080/1061186X.2020.1797049.. 

20. Wen S, Zhang T.Yu X, Dong W,Lan T,Fan J,Xue Y,Wang F,Dong L,Qin S*, Huang H*. The bone penetration of linezolid in osteoarticular tuberculosis patients of China. International Journal of Infectious Diseases.2021, 103:364-369. doi: 10.1016/j.ijid.2020.11.203.

21. Chen S,Teng T,Wen S,Zhang T, Huang H*.The aceE involves in mycolic acid synthesis and biofilm formation in Mycobacterium smegmatis. BMC Microbiology.2020

22. Zhou Z#, Li C#, Zhu R#,Wang D, Liu T,Jia J, Wang F,Zhao L,Dong L,Yu X*, Huang H*.Combination of percutaneous lung biopsy and Xpert MTB/RIF Ultra enhances differential diagnosis of tuberculosis: a prospective cohort study. Infectious Diseases and Therapy.2020, 9(4):797-806.  doi: 10.1007/s40121-020-00327-0

23. Jing W, Zong Z,Tang H,Wang J,Zhang T, Wen S,Xue Y,Chu N*,Zhao W*, Huang H*. Population Pharmacokinetic Analysis of Isoniazid among Pulmonary Tuberculosis Patients from China.Antimicrob Agents Chemother.,2020,64(3).pii:e01736-19.doi: 10.1128/AAC.01736-19. 

24. Wang G, Wang S, Yang X, Sun Q, Jiang G, Huang M, Huo F, Ma Y, Chen X*, Huang H*. Accuracy of Xpert MTB/RIF Ultra for the diagnosis of pleural tuberculosis in a multicentre cohort study. Chest, 2020 Feb;157(2):268-275. doi: 10.1016/j.chest.2019.07.027. 

25.Wang Y, Wang G, Wang Y, Xiao Jing, Sun L, Li J, Wen S, Zhang T,Ma Q, Huang H*, Shen A*.Development and clinical validation of multiple cross displacement amplification combined with nanoparticles-based biosensor for detection of Mycobacterium tuberculosis: preliminary results. Front. Microbiol. 2019，10:2135.doi: 10.3389/fmicb.2019.02135

26.  Sun Q, Wang S, Dong W, Jiang G, Huo F, Ma Y, Huang H*, Wang G*. Diagnostic value of Xpert MTB/RIF Ultra for osteoarticular tuberculosis. J Infect. 2019 ; 79(2):153-158.

27.  Zhang T, Jiang G, Wen S, Huo F, Wang F, Huang H*, Pang Y*. Para-aminosalicylic acid increases the susceptibility to isoniazid in clinical isolates  of Mycobacterium tuberculosis. Infect Drug Resist. 2019,12:825-829

28. Yu X, Gao X, Li C, Luo J,Wen S ,Zhang Z, Ma Y,Dong L,Wang F, Huang H*. In Vitro Activity of bedaquiline and delamanid against Non-tuberculous Mycobacteria isolated in Beijing, China. AAC,2019, 63(8). pii: e00031-19.

29. Pang Y, Jing W, Lu J, Zong Z, Huo F, Dong L, Dai G, Li Y,  Huang H*, Chu N*.No in vitro synergistic effect of bedaquiline combined with fluoroquinolones, linezolid, and clofazimine against extensively drug-resistant tuberculosis. Diagn Microbiol Infect Dis. 2019 Aug;94(4):361-364

30. Liu R, Liang Q, Shang Y, Ma Y, Wang F, Dong L, Huang H*, Gao M*, Pang Y*. GeneXpert of stool versus gastric lavage fluid for the diagnosis of pulmonary tuberculosis in severely ill adults. Infection. 2019 Aug;47(4):611-616.(IF:2.927) (IF：3.040)

31.     Wang G#, Wang S#, Jiang G#, Yang X#,Huang M, Huo F,Ma Y, Dai G, Li W, Chen X*, Huang H*. Xpert MTB/RIF Ultra improved the diagnosis of paucibacillary tuberculosis: a prospective cohort study. J Infect,2019,78(4):311-316 (IF:5.099) (IF：4.842)

32.   Dai G#, Chen S#, Dong L,Huo F, Shang Y,Huang H*. Determination of the critical concentration of rifabutin for susceptibility testing using the proportion method with Löwenstein-Jensen medium against Mycobacterium tuberculosis isolates. Lab Medicine，2019, 16;50(3):292-297

33.  Wen S, Jing W, Zhang T, Zong Z, Xue Y, Shang Y, Wang F, Huang H*, Chu N*, Pang Y*.Comparison of in vitro activity of the nitroimidazoles delamanid and pretomanid against multidrug-resistant and extensively drug-resistant tuberculosis. Eur J Clin Microbiol Infect Dis. 2019 Jul;38(7):1293-1296. 

34.  Huang H#, Ding N#, Yang T#, Li C#, Jia X#, Wang G#, Zhong J, Zhang J, Jiang G, Wang S, Zong Z, Jing W, Zhao Y, Xu S*, Chen F*. Cross-sectional whole-genome sequencing and epidemiological study of multidrug-resistant Mycobacterium tuberculosis in China. Clin Infect Dis. 2019,65:405-413

35. Sun L, Zhang L, Wang T, Jiao W, Li Q, Yin Q, Li J, Qi H, Xu F, Shen C, Xiao J, Liu S, Mokrousov I*, Huang H*, Shen A*. Mutations of Mycobacterium tuberculosis induced by anti-tuberculosis treatment result in metabolism changes and elevation of ethambutol resistance. Infect Genet Evol. 2019, 72:151-158. 

36.  Yang T,Zhong J, Zhang J, Li C, Yu X, Xiao J, Jia X, Ding N, Ma G, Wang G,Yue L, Liang Q, Sheng Y, Sun Y, Huang H*, Chen F*. Pan-genomic study of Mycobacterium tuberculosis reflecting the primary/secondary genes, generality/individuality, and the interconversion through copy number variations. Frontiers in Microbiology, 2018, 9:1886. doi: 10.3389/fmicb.2018.01886. 

37.  Zong Z, Huo F, Shi J, Jing W, Ma Y, Liang Q, Jiang G, Dai G, Huang H*, Pang Y. Relapse Versus Reinfection of Recurrent Tuberculosis Patients in a National TuberculosisSpecialized Hospital in Beijing, China. Front Microbiol. 2018;9:1858. doi: 10.3389/fmicb.2018.01858. eCollection 2018.

38.  Shi J, Lu J, Wen S, Zong Z, Huo F, Luo J, Liang Q, Li Y, Huang H*, Pang Y. In vitro activity of PBTZ169 against multiple Mycobacterium species. Antimicrob Agents Chemother. 2018,62(11). pii: AAC.01314-18.

39.  Wang G, Dong W, Lan T, Fan J,Tang K, Li Y,Yan G,Jiang G, Ma Y, Shang Y, Qin S*, Huang H*.Diagnostic accuracy evaluation of the conventional and molecular tests for Spinal Tuberculosis in a cohort, head-to-head study. Emerging Microbes & Infections ，2018，7(1):109-117. doi: 10.1038/s41426-018-0114-1 

40. Luo J,Yu X, Jiang G, Fu Y, Huo F, Ma Y,Wang F, Shang Y, Liang Q, Xue Y, Huang H*. In Vitro Activity of Clofazimine against Nontuberculous Mycobacteria in China. Antimicrob. Agents Chemother.2018，62(7). pii: e00072-18. 

41. Zong Z, Jing W, Shi J, Wen S, Zhang T, Huo F, Shang Y, Liang Q, Huang H*, Pang Y. Comparison of in vitro activity and MIC distributions between the novel oxazolidinone delpazolid and linezolid against multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis in China. Antimicrob Agents Chemother. 2018，62(8) . pii: AAC.00165-18. doi: 10.1128/AAC.00165-18. 

42.  Shi J, Dong W, Ma Y, Liang Q, Shang Y, Wang F, Huang H*, Pang Y.GeneXpert MTB/RIF Outperforms Mycobacterial Culture in Detecting Mycobacterium tuberculosis from Salivary Sputum. Biomed Res Int. 2018;1514381.

43. Wu X, Pang Y, Song Y, Dong W, Zhang T, Wen S, Huang H*, Gao M*. Implications of a school outbreak of multidrug-resistant tuberculosis in Northern China. Epidemiol Infect. 2018;146(5):584-588.

44.  Huo F, Luo J, Shi J, Zong Z, Wei Jing, Wenzhu Dong,Lingling Dong,Yifeng Ma, Qian Liang,Yuanyuan Shang, Huang H*,  Yu Pang. A 10-Year Comparative Analysis Shows that Increasing Prevalence of Rifampin-Resistant Mycobacterium tuberculosis in China Is Associated with the Transmission of Strains Harboring Compensatory Mutations. .Agents Chemother.2018,62(4). pii: e02303-17. . 

45.  Wang Q, Pang Y, Jing W,Liu Y,Wang N, Yin H, Zhang Q,Ye Z, Zhu, M, Li M, Liu P, Wu T, Chen C,Wu W,Qin Z,Qiu C, Deng Q, Xu T, Wang J, Guo R, Du Y, Wang J, Huang H, Chen X, and Chu N. Clofazimine for Treatment of Pulmonary Extensively Drug-Resistant Tuberculosis in China. Antimicrob. Agents Chemother. 2018,62(4). pii: e02149-17. .

46.  Wang G, Wang S, Jiang G, Fu Y, Shang S, Huang H*. Incremental cost-effectiveness of the second Xpert MTB/RIF assay to detect Mycobacterium tuberculosis. Journal of Thoracic Disease. 2018，10(3):1689-1695 

47.  Tan J#,Wu X#,Chen S,Gu M, Huang H*,Yue W*. Dominant epitopes derived from cell-wall protein LppZ for immunodiagnostic ofpulmonary tuberculosis. BMC Immunology,2018,19(1):10

48. Xia Yu#, Xiling Zeng#,Wenhui Shi, Yanjie Hu, Wenjuan Nie, Naihui Chu*,  Huang H*.Validation of Cycloserine Efficacy in Treatment of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis in Beijing, China. AAC 2018,62(3,pii: e01824-17 

49. Jing W#, Pang Y#, Zong Z, Wang J, Guo R, Huo F, Jiang G, Ma Y, Huang H*, Chu N*. Rifabutin Resistance Associated with Double Mutations in rpoB Gene in Mycobacterium tuberculosis Isolates. Front Microbiol. 2017,;8:1768. doi: 10.3389/fmicb.2017.01768

50.  Pang Y#, Lu J, Huo F, Ma Y, Zhao L, Li Y, Liang Q, Chu N, Gao M, Huang H*. Prevalence and treatment outcome of extensively drug-resistant tuberculosis plus additional drug resistance from the National Clinical Center for Tuberculosis in China: A five-year review. J Infect. 2017,75(5):433-440

51.  Pang Y#, Zong Z#, Huo F, Jing W, Ma Y, Dong L, Li Y, Zhao L, Fu Y, Huang H*. In vitro drug susceptibility of bedaquiline, delamanid, linezolid, clofazimine, moxifloxacin, and gatifloxacin against extensively drug –resistant tuberculosis from Beijing, China. Antimicrob Agents Chemother. 2017，61(10). 

52. Pang Y#, Shang Y#, Lu J, Liang Q, Dong L, Li Y, Zhao L, Jiang G, Huang H*. GeneXpert MTB/RIF assay in the diagnosis of urinary tuberculosis from urine specimens. Sci Rep. 2017，21;7(1):6181

53. Li H#,Wang X,Wang B,Fu L,Liu G,Lu Y,Cao M,Huang H*, Javid B*.Latently and uninfected healthcare workers exposed to tuberculosis make protective antibodies against Mycobacterium tuberculosis.PNAS,2017, 114(19):5023-5028 

54.  Li QJ, Jiao WW, Yin QQ, Li YJ, Li JQ, Xu F, Sun L, Xiao J, Qi H, Wang T, Mokrousov I, Huang H*, Shen AD*.Positive epistasis of major low-cost drug resistance mutations rpoB531-TTG and katG315-ACC depends on the phylogenetic background of mycobacterium tuberculosis strains. Int J Antimicrob Agents. 2017

55.  Chen H#, He L#, Huang H#, Shi C, Ni X, Dai G, Ma L, Li W. Mycobactrium tuberculosis Lineage Distribution in Xinjiang and Gansu Provinces, China. Sci Rep. 2017 Apr 21;7(1):1068. doi: 10.1038/s41598-017-00720-9

56.  Hu Y, Wu X, Luo J, Fu Y, Zhao L, Ma Y, Li Y, Liang Q,Shang Y, Huang H*. Detection of pyrazinamide resistance of Mycobacterium tuberculosis using nicotinamide as a surrogate. Clinical Microbiology and Infections.2017, 23(11):835-838

57.  Zeng X, Jing W, Zhang Y, Duan H, Lu Y, Dong Q, Huang H*, Chu N*. Performance of the MTBDRsl Line probe assay for rapid detection of resistance to second-line anti-tuberculosis drugs and ethambutol in China. Diagn Microbiol Infect Dis. 2017，89(2)112-117.

58.  Jia X, Yang L, Dong M, Chen S, Lv L, Cao D,Fu J, Yang J, Zhang J, Zhang X, Shang Y, Wang G, Sheng Y, Huang H*, Chen F. The bioinformatics analysis of comparative genomics of Mycobacterium tuberculosis complex (MTBC) provides insight into dissimilarities between intraspecific groups differing in host association, virulence and epitope diversity. Frontiers in Cellular and Infection Microbiology.2017,7:88.doi: 10.3389/fcimb.2017.00088

59. Chen S,Han Y,Yu D,Huo F,Wang F,Li Y,Dong L,Liu Z,Huang H*.Transdermal delivery of isoniazid and rifampin in guinea pigs by electro-phonophoresis. Drug Deliv. 2017,24:1, 467-470 

出版论著：

1.   《结核病研究进展报告.2020》，副主编， 北京，人民卫生出版社，2021年

2.   《结核病实验室检测与图解》主编，上海，上海科技出版社，2021年

3.   《非结核分枝杆菌病诊断与治疗》，副主编，北京，人民卫生出版社，2018年

获奖情况：

1.   “结核病诊断新技术的建立及推广应用”，北京医院科技奖（二等奖）（排名第一），2022年

2.   “非结核分枝杆菌病诊断技术的建立与应用推广”中国防痨协会科学技术奖（二等奖）（排名第一），2021年

3.   结核病诊疗关键技术的创新性研究；北京市科学技术奖（二等）（排名第四），2014年